logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1088 : PREDICTED: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) [Bos taurus]

[ CaMP Format ]

This entry is computationally expanded from SB0050

* Basic Information

OrganismBos taurus (cattle)
Protein Namesepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog; avian)
Gene NamesEGFR; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 1 mRNA, 8 ESTs, 8 Proteins
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
XP_592211 XM_592211 407217 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 1185 aa

Average Mass: 131.640 kDa

Monoisotopic Mass: 131.554 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Recep_L_domain 1. 34145139.11.4e-38
Furin-like 1. 161315270.63.6e-78
Recep_L_domain 2. 338458149.88.4e-42
Notch 1. 471493-17.45.6
EGF_2 1. 5395682.41.6
SKG6 1. 615649-6.74.5
Pkinase_Tyr 1. 689945441.99.7e-130
--- cleavage 710 (inside Pkinase_Tyr 689..945) ---

3. Sequence Information

Fasta Sequence: XSB1088.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] GTVYKGLWIP710-EGEKVKIPVA

Pro710 Glu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Gly701Thr702Val703Tyr704Lys705Gly706Leu707Trp708Ile709Pro710
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Glu711Gly712Glu713Lys714Val715Lys716Ile717Pro718Val719Ala720

Sequence conservation (by blast)

[Site 2] LIEDSMDDTF1061-LPVPEYVNQS

Phe1061 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Leu1052Ile1053Glu1054Asp1055Ser1056Met1057Asp1058Asp1059Thr1060Phe1061
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu1062Pro1063Val1064Pro1065Glu1066Tyr1067Val1068Asn1069Gln1070Ser1071

Sequence conservation (by blast)

* References

None.