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XSB1089 : v-erbB gene product [Rous-associated virus type 1]

[ CaMP Format ]

This entry is computationally expanded from SB0050

* Basic Information

OrganismRous-associated virus type 1
Protein NamesV-erbB protein
Gene Namesv-erbB
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAC60727 N/A N/A Q86714 N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 567 aa

Average Mass: 63.391 kDa

Monoisotopic Mass: 63.350 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
GSu_C4xC__C2xCH 1. 2047-13.44.8
Adeno_E3_CR2 1. 62102-2.41.6
Pkinase_Tyr 1. 137393445.96.2e-131
--- cleavage 158 (inside Pkinase_Tyr 137..393) ---
CRT-like 1. 454560-77.83.5

3. Sequence Information

Fasta Sequence: XSB1089.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] GTVYKGLWIP158-EGEKVKIPVA

Pro158 Glu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Gly149Thr150Val151Tyr152Lys153Gly154Leu155Trp156Ile157Pro158
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Glu159Gly160Glu161Lys162Val163Lys164Ile165Pro166Val167Ala168

Sequence conservation (by blast)

* References

[PubMed ID: 8152791] Vennstrom B, Raynoscheck C, Jansson L, Doederlein G, Lhotak V, Johnsson A, Beug H, Retroviral capture of c-erbB proto-oncogene sequences: rapid evolution of distinct viral genomes carrying mutant v-erbB genes with different transforming capacities. Oncogene. 1994 May;9(5):1307-20.