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XSB1090 : epidermal growth factor receptor precursor - chicken

[ CaMP Format ]

This entry is computationally expanded from SB0050

* Basic Information

OrganismGallus gallus (chicken)
Protein Namesepidermal growth factor receptor precursor
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
TVCHLV N/A N/A N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 1223 aa

Average Mass: 136.090 kDa

Monoisotopic Mass: 136.002 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Recep_L_domain 1. 63175156.39.4e-44
Furin-like 1. 191345272.21.2e-78
Recep_L_domain 2. 368488151.91.9e-42
Toxin_30 1. 558590-5.98.4
GSu_C4xC__C2xCH 1. 604631-13.44.8
Adeno_E3_CR2 1. 646686-2.41.6
Pkinase_Tyr 1. 721977449.54.9e-132
--- cleavage 742 (inside Pkinase_Tyr 721..977) ---
CRT-like 1. 10381144-77.83.5

3. Sequence Information

Fasta Sequence: XSB1090.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] GTVYKGLWIP742-EGEKVKIPVA

Pro742 Glu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Gly733Thr734Val735Tyr736Lys737Gly738Leu739Trp740Ile741Pro742
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Glu743Gly744Glu745Lys746Val747Lys748Ile749Pro750Val751Ala752

Sequence conservation (by blast)

* References

[PubMed ID: 2988784] Nilsen TW, Maroney PA, Goodwin RG, Rottman FM, Crittenden LB, Raines MA, Kung HJ, c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor. Cell. 1985 Jul;41(3):719-26.

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