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XSB1096 : epidermal growth factor receptor [Xiphophorus xiphidium]

[ CaMP Format ]

This entry is computationally expanded from SB0050

* Basic Information

OrganismXiphophorus xiphidium
Protein Namesepidermal growth factor receptor
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAP55673 N/A N/A Q6XJV8 N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 1209 aa

Average Mass: 134.176 kDa

Monoisotopic Mass: 134.089 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Recep_L_domain 1. 67178124.24.1e-34
Furin-like 1. 194348265.21.5e-76
Recep_L_domain 2. 371490129.21.3e-35
CXC 1. 510553-19.310
SapA 1. 584610-7.51.3
C_tripleX 1. 6246390.248
PetG 1. 6536885.09.8
Pkinase_Tyr 1. 722978454.12e-133
--- cleavage 743 (inside Pkinase_Tyr 722..978) ---

3. Sequence Information

Fasta Sequence: XSB1096.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] GTVYKGLWVP743-EGEDVKIPVA

Pro743 Glu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Gly734Thr735Val736Tyr737Lys738Gly739Leu740Trp741Val742Pro743
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Glu744Gly745Glu746Asp747Val748Lys749Ile750Pro751Val752Ala753

Sequence conservation (by blast)

* References

[PubMed ID: 14660701] Gomez A, Volff JN, Hornung U, Schartl M, Wellbrock C, Identification of a second egfr gene in Xiphophorus uncovers an expansion of the epidermal growth factor receptor family in fish. Mol Biol Evol. 2004 Feb;21(2):266-75. Epub 2003 Dec 5.