CaMPDB :: Substrate

XSB1144 : glutamate receptor, ionotropic, NMDA2A (epsilon 1) [Mus musculus]

This entry is computationally expanded from SB0072

* Basic Information

Organism	Mus musculus (house mouse)
Protein Names	Glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; NMDAR2A; NR2A; glutamate receptor; ionotropic; NMDA2A (epsilon 1); GluRepsilon1
Gene Names	Grin2a; glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Gene Locus	16 3.4 cM; chromosome 16
GO Function	Not available

Entrez Protein	Entrez Nucleotide	Entrez Gene	UniProt	OMIM	HGNC	HPRD	KEGG
NP_032196	NM_008170	14811	P35436	N/A	N/A	N/A	mmu:14811

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 1464 aa

Average Mass: 165.421 kDa

Monoisotopic Mass: 165.316 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain name	begin	end	score	e-value
HS1_rep 1.	179	215	6.7	3.1
Lig_chan-Glu_bd 1.	439	502	80.6	5.5e-21
Lig_chan 1.	554	838	375.4	9.9e-110
NMDAR2_C 1.	839	1464	1166.2	0
--- cleavage 1329 (inside NMDAR2_C 839..1464) ---
--- cleavage 1278 (inside NMDAR2_C 839..1464) ---

3. Sequence Information

Fasta Sequence: XSB1144.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] LEGNLYGSLF¹³²⁹-SVPSSKLLGN

Phe¹³²⁹ Ser

P10	P9	P8	P7	P6	P5	P4	P3	P2	P1

Leu¹³²⁰	Glu¹³²¹	Gly¹³²²	Asn¹³²³	Leu¹³²⁴	Tyr¹³²⁵	Gly¹³²⁶	Ser¹³²⁷	Leu¹³²⁸	Phe¹³²⁹

P1'	P2'	P3'	P4'	P5'	P6'	P7'	P8'	P9'	P10'
Ser¹³³⁰	Val¹³³¹	Pro¹³³²	Ser¹³³³	Ser¹³³⁴	Lys¹³³⁵	Leu¹³³⁶	Leu¹³³⁷	Gly¹³³⁸	Asn¹³³⁹

Sequence conservation (by blast) Sequence conservation (by blast)

Reference peptide (cleaved bond±30 residues)
REIDLSRPSRSISLKDRERLLEGNLYGSLFSVPSSKLLGNKSSLFPQGLEDSKRSKSLLP

Summary

#	organism	max score	hits	top seq
1	N/A	117.00	4	1
2	Rattus norvegicus	117.00	4	N-methyl-D-aspartate receptor NMDAR2A subunit; NMD
3	NMDA	117.00	3	NMDE1_RAT Glutamate
4	Mus musculus	117.00	2	glutamate receptor, ionotropic, NMDA2A (epsilon 1)
5	Canis familiaris	112.00	1	PREDICTED: similar to glutamate receptor, ionotrop
6	Saimiri boliviensis	111.00	1	glutamate receptor ionotropic N-methyl-D-aspartate
7	Homo sapiens	110.00	2	N-methyl-D-aspartate receptor subunit 2A precursor
8	Pan troglodytes	110.00	1	N-methyl-D-aspartate receptor subunit 2A
9	Monodelphis domestica	105.00	1	PREDICTED: similar to N-methyl-D-aspartate recepto
10	Bos taurus	105.00	1	PREDICTED: similar to N-methyl-D-aspartate recepto
11	Gallus gallus	85.90	1	PREDICTED: similar to N-methyl-D-aspartate recepto
12	Danio rerio	72.00	2	PREDICTED: similar to N-methyl-D-aspartate recepto
13	Tetraodon nigroviridis	50.40	1	unnamed protein product

Top-ranked sequences

organism	matching
N/A	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359
Rattus norvegicus	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359
NMDA	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359
Mus musculus	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359
Canis familiaris	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\| Sbjct 1300 REMDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLSGNKSSLFPQGLEDRKRSKSLLP 1359
Saimiri boliviensis	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|#\|\|\|\|\|\|\| \| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 1224 REIDLSRPSRSISLKDRERLLEGNFYGSLF#SVPSSKLSGKKSSLFPQGLEDSKRSKSLLP 1283
Homo sapiens	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|#\|\|\|\|\|\|\| \| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 1300 RELDLSRPSRSISLKDRERLLEGNFYGSLF#SVPSSKLSGKKSSLFPQGLEDSKRSKSLLP 1359
Pan troglodytes	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|#\|\|\|\|\|\|\| \| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 1300 RELDLSRPSRSISLKDRERLLEGNFYGSLF#SVPSSKLSGKKSSLFPQGLEDSKRSKSLLP 1359
Monodelphis domestica	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|\|\|\| \|\|\|\|\|\|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\| \|\|\| \| \|\|\|+\|\|\|\|\|\| \| Sbjct 1305 REIDLGRPSRSISLKDKERLLEGNLYGSLF#SVPSSKLLGNKGSLFSQALEDTKRSKSLFP 1364
Bos taurus	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|+\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| \|\|\| \|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\| Sbjct 1072 REVDPSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLAGNKGSLFPQGLEVGKRSKSLLP 1131
Gallus gallus	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 \|\|\|\|\| \|\|\|\|\|\|\|\|\|\|+\|+ \|+ + \| \|+\|#\|\|\|\|\|\|\|\| \|\|+\|\| \|\|\|\|\|\|\|\|\|\| \| Sbjct 1294 REIDLGRPSRSISLKDKEKFLQSSPYASMF#SVPSSKLLSNKASLLTHALEDSKRSKSLYP 1353
Danio rerio	Query 1300 REIDLSRPSRSISLKDRERLLEGNLYGSLF#SVPSSKLLGNKSSLFPQGLEDSKRSKSLLP 1359 +\|\|\|\|+\|\|+\|\|+\|\|\|+++\| \|\| + \| ++\|#++ + \|\| \|++\| \|\| + \|\|+\|\|\|\|\|\|\| \| Sbjct 1289 KEIDLNRPARSVSLKEKDRFLEDSPYANMF#NIKADKLFGSRSMLFNRNLEESKRSKSLYP 1348
Tetraodon nigroviridis	Query 1300 REIDLSRPSRSISLKDRERLLEGNL-YGSLF#SVP--SSKLLG--NKSSLFPQGLEDSKRS 1354 +++\|+ \|\|+\|\|+\|\|\|+++\| + \| +\|\|#++ \| +\| \| +\|\| +\| \|\|+\|\|\|\| Sbjct 1216 KDVDVGRPARSVSLKEKDRFATSDSHYANLF#NMRPYSGRLFGTSSKSMMFNHNLEESKRS 1275 Query 1355 KSLLP 1359 \|\|\| \| Sbjct 1276 KSLYP 1280

[Site 2] QDWSQNNALQ¹²⁷⁸-FQKNKLKINR

Gln¹²⁷⁸ Phe

P10	P9	P8	P7	P6	P5	P4	P3	P2	P1

Gln¹²⁶⁹	Asp¹²⁷⁰	Trp¹²⁷¹	Ser¹²⁷²	Gln¹²⁷³	Asn¹²⁷⁴	Asn¹²⁷⁵	Ala¹²⁷⁶	Leu¹²⁷⁷	Gln¹²⁷⁸

P1'	P2'	P3'	P4'	P5'	P6'	P7'	P8'	P9'	P10'
Phe¹²⁷⁹	Gln¹²⁸⁰	Lys¹²⁸¹	Asn¹²⁸²	Lys¹²⁸³	Leu¹²⁸⁴	Lys¹²⁸⁵	Ile¹²⁸⁶	Asn¹²⁸⁷	Arg¹²⁸⁸

Sequence conservation (by blast) Sequence conservation (by blast)

Reference peptide (cleaved bond±30 residues)
DEDQMLQETGNPATREEAYQQDWSQNNALQFQKNKLKINRQHSYDNILDKPREIDLSRPS

Summary

#	organism	max score	hits	top seq
1	Mus musculus	127.00	2	glutamate receptor, ionotropic, NMDA2A (epsilon 1)
2	NMDA	124.00	6	NMDE1_RAT Glutamate
3	N/A	124.00	5	1
4	Rattus norvegicus	124.00	4	N-methyl-D-aspartate receptor NMDAR2A subunit; NMD
5	Saimiri boliviensis	116.00	1	glutamate receptor ionotropic N-methyl-D-aspartate
6	Homo sapiens	113.00	4	N-methyl-D-aspartate receptor subunit 2A precursor
7	Pan troglodytes	113.00	2	N-methyl-D-aspartate receptor subunit 2A
8	Canis familiaris	110.00	1	PREDICTED: similar to glutamate receptor, ionotrop
9	Bos taurus	108.00	2	PREDICTED: similar to N-methyl-D-aspartate recepto
10	Monodelphis domestica	101.00	1	PREDICTED: similar to N-methyl-D-aspartate recepto
11	Gallus gallus	84.00	1	PREDICTED: similar to N-methyl-D-aspartate recepto
12	Danio rerio	53.90	2	PREDICTED: similar to N-methyl-D-aspartate recepto
13	Tetraodon nigroviridis	48.90	1	unnamed protein product
14	Macaca mulatta	35.00	1	PREDICTED: N-methyl-D-aspartate receptor subunit 2
15	Tetrahymena thermophila SB210	33.90	1	TBC domain containing protein
16	Paramecium tetraurelia	33.50	1	hypothetical protein
17	Canis lupus familiaris	32.70	1	N-methyl-D-aspartate receptor subunit 2B

Top-ranked sequences

organism	matching
Mus musculus	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPREIDLSRPS 1308 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPREIDLSRPS 1308
NMDA	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPREIDLSRPS 1308 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 1249 DEDQMLQETGNPATREEVYQQDWSQNNALQ#FQKNKLRINRQHSYDNILDKPREIDLSRPS 1308
N/A	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPREIDLSRPS 1308 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQNSYDNILDKPREIDLSRPS 1308
Rattus norvegicus	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPREIDLSRPS 1308 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 1249 DEDQMLQETGNPATREEVYQQDWSQNNALQ#FQKNKLRINRQHSYDNILDKPREIDLSRPS 1308
Saimiri boliviensis	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPREIDLSRPS 1308 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+ \|\|\|\|\|+\|\|\|\|\|\|# \|\|\|\|\|+\|+\|\|\|\|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 1173 DEDQMLQETGNPATREQVYQQDWAQNNALQ#LQKNKLRISRQHSYDNIVDKPREIDLSRPS 1232
Homo sapiens	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPREIDLSRPS 1308 \|\|\|\|\|\|\|\|\|\|\|\|\|\| \|+ \|\|\|\|\|+\|\|\|\|\|\|# \|\|\|\|\|+\|+\|\|\|\|\|\|\|\|+\|\|\|\|\|+\|\|\|\|\|\| Sbjct 1249 DEDQMLQETGNPATGEQVYQQDWAQNNALQ#LQKNKLRISRQHSYDNIVDKPRELDLSRPS 1308
Pan troglodytes	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPREIDLSRPS 1308 \|\|\|\|\|\|\|\|\|\|\|\|\|\| \|+ \|\|\|\|\|+\|\|\|\|\|\|# \|\|\|\|\|+\|+\|\|\|\|\|\|\|\|+\|\|\|\|\|+\|\|\|\|\|\| Sbjct 1249 DEDQMLQETGNPATGEQVYQQDWAQNNALQ#LQKNKLRISRQHSYDNIVDKPRELDLSRPS 1308
Canis familiaris	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPREIDLSRPS 1308 \|\|\|\|\|\|\|\|\|\|+\|\| +\|\| \|\|\|\|\|+\|\|+ \|\|#\|\|\|\|\|\|+\|+\|\|\|\|\|\|\|\|+\|\|\|\|\|+\|\|\|\|\|\| Sbjct 1249 DEDQMLQETGSPAAQEEVYQQDWAQNSTLQ#FQKNKLRISRQHSYDNIVDKPREMDLSRPS 1308
Bos taurus	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPREIDLSRPS 1308 \|\|\|\|\|\|\|\|\|\|\|\|\| +\|\| \|\|\|\|\|+ \|+\|\|\|# \|\|\|\|\|+\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\| \|\|\|\| Sbjct 1021 DEDQMLQETGNPAAQEEVYQQDWAPNSALQ#LQKNKLRISRQHSYDNILDKPREVDPSRPS 1080
Monodelphis domestica	Query 1249 DEDQMLQET-GNPATREEAYQQDWSQNNALQ#FQK-NKLKINRQHSYDNILDKPREIDLSR 1306 \|\|\|\|\|\|\|\|\| \|\|\| \|\| \|+\|\|\|+\|\|\|\|\|\|#\|\|\| \|\|\|+\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| \| Sbjct 1252 DEDQMLQETTANPAHPEETYEQDWAQNNALQ#FQKKNKLRISRQHSYDNILDKPREIDLGR 1311 Query 1307 PS 1308 \|\| Query 1307 PS 1308
Gallus gallus	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#F-QKNKLKINRQHSYDNILDKPREIDLSRP 1307 +\|\|\|\|\|\|+\| \| + \|\| \| \|\|\|\|\|\|\|\|#+ +\|\|\|\|+\|+\|\|\|\|+\|\|\| \|\| \|\|\|\|\| \|\| Sbjct 1242 EEDQMLQDTTNLSLPEEIYGHSWSQNNALQ#YHKKNKLRISRQHSFDNIADKSREIDLGRP 1301 Query 1308 S 1308 \| Query 1308 S 1308
Danio rerio	Query 1250 EDQMLQETG-NPATR-EEAYQQDWSQNNALQ#FQK-NKLKINRQHSYDNI-LDKPREIDLS 1305 \|\|\|\|\|\|\| +\|+ ++ + \| \| + # \|+ \|+\|\|++\|\|\|\|+\|\|\| \|+\|\|+\|\|\|\|+ Sbjct 1235 EDQMLQEAMISPSMHHDDMFSHYWPQTDGPH#VQRRNRLKLSRQHSFDNIMLEKPKEIDLN 1294 Query 1306 RPS 1308 \|\|+ Sbjct 1295 RPA 1297
Tetraodon nigroviridis	Query 1249 DEDQMLQET-GNPATREEAYQQD-------WSQNNALQ#FQK-NKLKINRQHSYDNI-LDK 1298 +\|\|\|+\| + \|+\| + \|\| \| \| + # \|\| \|+\|+++\|\|\|\|+\|\|\| \|+\| Sbjct 1155 NEDQLLTDPLGSPTLHHQQQQQADEMFGLYWPQTDGPH#VQKRNRLRLSRQHSFDNIMLEK 1214 Query 1299 PREIDLSRPS 1308 \|+++\|+ \|\|+ Sbjct 1215 PKDVDVGRPA 1224
Macaca mulatta	Query 1250 EDQMLQETGNPA------TREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPRE 1301 \|\| \|\|\| \|\| + + \| \|+ # +\|\|+ \|+ \|\|\|\|\|\| +\| +\| Sbjct 1256 EDNSLQELDQPAAPVAVTSNASTTKYPQSPTNSKA#QKKNRNKLRRQHSYDTFVDLQKE 1313
Tetrahymena thermophila SB210	Query 1249 DEDQMLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKIN 1287 +\|+\|++\|+ \|\|\|+\|\| \| \|+ \|# \|\| \|+\| Sbjct 648 NENQLIQQQKPPATQEEDYSVPQELQNSFQ#MNKNMSKLN 686
Paramecium tetraurelia	Query 1253 MLQETGNPATREEAYQQDWSQNNALQ#FQKNKLKINRQHSY--DNILDKPREIDLS 1305 +\|\|+ \| ++ + \|\| \|\|#\|\|+\|+ +\|+\| + ++\|++\| ++\|\|\|\| Sbjct 165 ILQKQVNDLHKDNIFLGSEKQNLLLQ#FQQNQQFVNQQQNILEEDIINKTQQIDLS 219
Canis lupus familiaris	Query 1250 EDQMLQETGNPA------TREEAYQQDWSQNNALQ#FQKNKLKINRQHSYDNILDKPRE 1301 \|\| \|\|\| \|\| + + + \| \|+ # +\| + \|+ \|\|\|\|\|\| +\| +\| Sbjct 1256 EDNSLQELDQPAAPVAVPSNAPSTKYPQSPTNSKA#QKKTRNKLRRQHSYDTFVDLQKE 1313

* References

[PubMed ID: 19276107] Cho KK, Khibnik L, Philpot BD, Bear MF, The ratio of NR2A/B NMDA receptor subunits determines the qualities of ocular dominance plasticity in visual cortex. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5377-82. Epub 2009 Mar 10.

» More (9) « Hide Below

[PubMed ID: 19240213] ... Barros CS, Calabrese B, Chamero P, Roberts AJ, Korzus E, Lloyd K, Stowers L, Mayford M, Halpain S, Muller U, Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4507-12. Epub 2009 Feb 24.

[PubMed ID: 18773961] ... Altafaj X, Ortiz-Abalia J, Fernandez M, Potier MC, Laffaire J, Andreu N, Dierssen M, Gonzalez-Garcia C, Cena V, Marti E, Fillat C, Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome. Neurobiol Dis. 2008 Dec;32(3):377-84. Epub 2008 Aug 16.

[PubMed ID: 18603407] ... Sato A, Sekine Y, Saruta C, Nishibe H, Morita N, Sato Y, Sadakata T, Shinoda Y, Kojima T, Furuichi T, Cerebellar development transcriptome database (CDT-DB): profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum. Neural Netw. 2008 Oct;21(8):1056-69. Epub 2008 Jun 4.

[PubMed ID: 18851757] ... Liaw WJ, Zhu XG, Yaster M, Johns RA, Gauda EB, Tao YX, Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein. Mol Pain. 2008 Oct 14;4:45.

[PubMed ID: 7510577] ... Watanabe M, Mishina M, Inoue Y, Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina. Brain Res. 1994 Jan 21;634(2):328-32.

[PubMed ID: 1493227] ... Watanabe M, Inoue Y, Sakimura K, Mishina M, Developmental changes in distribution of NMDA receptor channel subunit mRNAs. Neuroreport. 1992 Dec;3(12):1138-40.

[PubMed ID: 1385220] ... Ikeda K, Nagasawa M, Mori H, Araki K, Sakimura K, Watanabe M, Inoue Y, Mishina M, Cloning and expression of the epsilon 4 subunit of the NMDA receptor channel. FEBS Lett. 1992 Nov 16;313(1):34-8.

[PubMed ID: 1377365] ... Kutsuwada T, Kashiwabuchi N, Mori H, Sakimura K, Kushiya E, Araki K, Meguro H, Masaki H, Kumanishi T, Arakawa M, et al., Molecular diversity of the NMDA receptor channel. Nature. 1992 Jul 2;358(6381):36-41.

[PubMed ID: 1374164] ... Meguro H, Mori H, Araki K, Kushiya E, Kutsuwada T, Yamazaki M, Kumanishi T, Arakawa M, Sakimura K, Mishina M, Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs. Nature. 1992 May 7;357(6373):70-4.