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XSB1163 : Chain A, X-Ray Structure Of Full-Length Annexin 1

[ CaMP Format ]

This entry is computationally expanded from SB0048

* Basic Information

OrganismSus scrofa (pig)
Protein NamesAnnexin A1; Annexin-1; Annexin I; Lipocortin I; Calpactin II; Chromobindin-9; p35; Phospholipase A2 inhibitory protein
Gene NamesANX1
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
1HM6_A N/A N/A P19619 N/A N/A N/A ssc:

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 346 aa

Average Mass: 38.744 kDa

Monoisotopic Mass: 38.720 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
--- cleavage 26 ---
Annexin 1. 4611194.73.1e-25
Annexin 2. 118183119.01.5e-32
Annexin 3. 20126780.36.8e-21
Annexin 4. 277342119.88.9e-33

3. Sequence Information

Fasta Sequence: XSB1163.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1HM6 (X-ray; 180 A; A/B=1-346), 1MCX (X-ray; 203 A; A=1-346)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] EEQEYIKTVK26-GSKGGPGSAV

Lys26 Gly

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu17Glu18Gln19Glu20Tyr21Ile22Lys23Thr24Val25Lys26
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Gly27Ser28Lys29Gly30Gly31Pro32Gly33Ser34Ala35Val36

Sequence conservation (by blast)

* References

[PubMed ID: 11053851] Rosengarth A, Luecke H, Crystallization and preliminary X-ray analysis of full-length annexin I comprising the core and N-terminal domain. Acta Crystallogr D Biol Crystallogr. 2000 Nov;56(Pt 11):1459-61.

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