logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1171 : PREDICTED: similar to merlin isoform 1 [Bos taurus]

[ CaMP Format ]

This entry is computationally expanded from SB0009

* Basic Information

OrganismBos taurus (cattle)
Protein Namessimilar to merlin isoform 1
Gene NamesNF2; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 2 mRNAs, 13 ESTs, 16 Proteins
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
XP_611643 XM_611643 540479 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 638 aa

Average Mass: 74.626 kDa

Monoisotopic Mass: 74.579 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
FERM_N 1. 6314469.01.8e-17
FERM_M 1. 146264141.82.1e-39
FERM_C 1. 268357177.53.8e-50
--- cleavage 336 (inside FERM_C 268..357) ---
--- cleavage 340 (inside FERM_C 268..357) ---
ERM 1. 389638345.31.2e-100

3. Sequence Information

Fasta Sequence: XSB1171.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] FNSSKLRVNK336-LILQLCIGNH

Lys336 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Phe327Asn328Ser329Ser330Lys331Leu332Arg333Val334Asn335Lys336
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu337Ile338Leu339Gln340Leu341Cys342Ile343Gly344Asn345His346

Sequence conservation (by blast)

[Site 2] KLRVNKLILQ340-LCIGNHDLFM

Gln340 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys331Leu332Arg333Val334Asn335Lys336Leu337Ile338Leu339Gln340
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu341Cys342Ile343Gly344Asn345His346Asp347Leu348Phe349Met350

Sequence conservation (by blast)

* References

None.