logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1180 : PREDICTED: similar to neurofibromin 2 isoform 5 isoform 11 [Canis familiaris]

[ CaMP Format ]

This entry is computationally expanded from SB0009

* Basic Information

OrganismCanis lupus familiaris (dog)
Protein Namessimilar to neurofibromin 2 isoform 5 isoform 11
Gene NamesLOC477535; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 11 mRNAs, 31 ESTs, 107 Proteins
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
XP_865545 XM_860452 477535 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 549 aa

Average Mass: 64.118 kDa

Monoisotopic Mass: 64.077 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
FERM_M 1. 62180141.82.1e-39
FERM_C 1. 184273177.63.5e-50
--- cleavage 252 (inside FERM_C 184..273) ---
--- cleavage 256 (inside FERM_C 184..273) ---
ERM 1. 305538294.22.8e-85

3. Sequence Information

Fasta Sequence: XSB1180.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] FNSSKLRVNK252-LILQLCIGNH

Lys252 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Phe243Asn244Ser245Ser246Lys247Leu248Arg249Val250Asn251Lys252
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu253Ile254Leu255Gln256Leu257Cys258Ile259Gly260Asn261His262

Sequence conservation (by blast)

[Site 2] KLRVNKLILQ256-LCIGNHDLFM

Gln256 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys247Leu248Arg249Val250Asn251Lys252Leu253Ile254Leu255Gln256
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu257Cys258Ile259Gly260Asn261His262Asp263Leu264Phe265Met266

Sequence conservation (by blast)

* References

None.