logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1181 : PREDICTED: similar to neurofibromin 2 isoform 1 isoform 13 [Canis familiaris]

[ CaMP Format ]

This entry is computationally expanded from SB0009

* Basic Information

OrganismCanis lupus familiaris (dog)
Protein Namessimilar to neurofibromin 2 isoform 1 isoform 13
Gene NamesLOC477535; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 11 mRNAs, 31 ESTs, 107 Proteins
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
XP_865579 XM_860486 477535 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 629 aa

Average Mass: 73.454 kDa

Monoisotopic Mass: 73.408 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
FERM_N 1. 2610679.31.4e-20
FERM_M 1. 108226141.82.1e-39
FERM_C 1. 230319177.63.5e-50
--- cleavage 298 (inside FERM_C 230..319) ---
--- cleavage 302 (inside FERM_C 230..319) ---
Phospho_p8 1. 325376-18.58.8
ERM 1. 385629331.61.6e-96

3. Sequence Information

Fasta Sequence: XSB1181.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] FNSSKLRVNK298-LILQLCIGNH

Lys298 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Phe289Asn290Ser291Ser292Lys293Leu294Arg295Val296Asn297Lys298
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu299Ile300Leu301Gln302Leu303Cys304Ile305Gly306Asn307His308

Sequence conservation (by blast)

[Site 2] KLRVNKLILQ302-LCIGNHDLFM

Gln302 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys293Leu294Arg295Val296Asn297Lys298Leu299Ile300Leu301Gln302
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu303Cys304Ile305Gly306Asn307His308Asp309Leu310Phe311Met312

Sequence conservation (by blast)

* References

None.