logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1183 : PREDICTED: similar to neurofibromin 2 isoform 6 isoform 7 [Canis familiaris]

[ CaMP Format ]

This entry is computationally expanded from SB0009

* Basic Information

OrganismCanis lupus familiaris (dog)
Protein Namessimilar to neurofibromin 2 isoform 6 isoform 7
Gene NamesLOC477535; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 11 mRNAs, 31 ESTs, 107 Proteins
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
XP_865475 XM_860382 477535 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 550 aa

Average Mass: 64.310 kDa

Monoisotopic Mass: 64.269 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
FERM_M 1. 64181100.75e-27
FERM_C 1. 185274177.63.5e-50
--- cleavage 253 (inside FERM_C 185..274) ---
--- cleavage 257 (inside FERM_C 185..274) ---
ERM 1. 306539294.22.8e-85

3. Sequence Information

Fasta Sequence: XSB1183.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] FNSSKLRVNK253-LILQLCIGNH

Lys253 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Phe244Asn245Ser246Ser247Lys248Leu249Arg250Val251Asn252Lys253
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu254Ile255Leu256Gln257Leu258Cys259Ile260Gly261Asn262His263

Sequence conservation (by blast)

[Site 2] KLRVNKLILQ257-LCIGNHDLFM

Gln257 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys248Leu249Arg250Val251Asn252Lys253Leu254Ile255Leu256Gln257
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu258Cys259Ile260Gly261Asn262His263Asp264Leu265Phe266Met267

Sequence conservation (by blast)

* References

None.