logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1197 : merlin [Xenopus laevis]

[ CaMP Format ]

This entry is computationally expanded from SB0009

* Basic Information

OrganismXenopus laevis (African clawed frog)
Protein Namesmerlin
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAU13782 N/A N/A Q64F50 N/A N/A N/A xla:

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 610 aa

Average Mass: 71.482 kDa

Monoisotopic Mass: 71.437 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
FERM_N 1. 2610280.17.7e-21
FERM_M 1. 104222147.54.2e-41
FERM_C 1. 226315174.04.2e-49
--- cleavage 294 (inside FERM_C 226..315) ---
--- cleavage 298 (inside FERM_C 226..315) ---
ERM 1. 347610189.21.2e-53

3. Sequence Information

Fasta Sequence: XSB1197.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] FNSSKLRVNK294-LILQLCIGNH

Lys294 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Phe285Asn286Ser287Ser288Lys289Leu290Arg291Val292Asn293Lys294
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu295Ile296Leu297Gln298Leu299Cys300Ile301Gly302Asn303His304

Sequence conservation (by blast)

[Site 2] KLRVNKLILQ298-LCIGNHDLFM

Gln298 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys289Leu290Arg291Val292Asn293Lys294Leu295Ile296Leu297Gln298
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu299Cys300Ile301Gly302Asn303His304Asp305Leu306Phe307Met308

Sequence conservation (by blast)

* References

None.