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XSB1200 : protein kinase C, gamma [Mus musculus]

[ CaMP Format ]

This entry is computationally expanded from SB0089

* Basic Information

OrganismMus musculus (house mouse)
Protein NamesProtein kinase C gamma type; PKC-gamma; 2.7.11.13; protein kinase C; gamma
Gene NamesPrkcc; Pkcc, Pkcg, Prkcc; Pkcc; Pkcg; protein kinase C, gamma
Gene Locus7 2.0 cM; chromosome 7
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_035232 NM_011102 18752 P63318 N/A N/A N/A mmu:18752

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 697 aa

Average Mass: 78.358 kDa

Monoisotopic Mass: 78.307 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
C1_1 1. 368887.16e-23
C1_1 2. 10115389.01.6e-23
C2 1. 173260139.79.1e-39
--- cleavage 338 ---
--- cleavage 321 ---
Pkinase 1. 351614275.41.3e-79
Pkinase_C 1. 63467952.41.7e-12

3. Sequence Information

Fasta Sequence: XSB1200.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] PSPTDSKRCF338-FGASPGRLHI

Phe338 Phe

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Pro329Ser330Pro331Thr332Asp333Ser334Lys335Arg336Cys337Phe338
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Phe339Gly340Ala341Ser342Pro343Gly344Arg345Leu346His347Ile348

Sequence conservation (by blast)

[Site 2] YERVRMGPSS321-SPIPSPSPSP

Ser321 Ser

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Tyr312Glu313Arg314Val315Arg316Met317Gly318Pro319Ser320Ser321
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ser322Pro323Ile324Pro325Ser326Pro327Ser328Pro329Ser330Pro331

Sequence conservation (by blast)

* References

[PubMed ID: 19088125] Medina CF, Mazerolle C, Wang Y, Berube NG, Coupland S, Gibbons RJ, Wallace VA, Picketts DJ, Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome. Hum Mol Genet. 2009 Mar 1;18(5):966-77. Epub 2008 Dec 16.

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