XSB1248 : Protein kinase C alpha type
[ CaMP Format ]
This entry is computationally expanded from SB0055
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | PKC-alpha; PKC-A; 2.7.11.13 |
| Gene Names | Pkca |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 672 aa
Average Mass: 76.852 kDa
Monoisotopic Mass: 76.802 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| C1_1 1. | 37 | 89 | 83.2 | 9.4e-22 |
| C1_1 2. | 102 | 154 | 88.8 | 1.9e-23 |
| C2 1. | 173 | 260 | 137.5 | 4.3e-38 |
| --- cleavage 316 --- | ||||
| --- cleavage 309 --- | ||||
| --- cleavage 324 --- | ||||
| Pkinase 1. | 339 | 597 | 289.5 | 7.3e-84 |
| Pkinase_C 1. | 617 | 662 | 55.8 | 1.6e-13 |
3. Sequence Information
Fasta Sequence: XSB1248.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
3 [sites]
Cleavage sites (±10aa)
[Site 1] KAKLGPVGNK316-VISPSEDRKQ
Lys316 
Val
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Lys307 | Ala308 | Lys309 | Leu310 | Gly311 | Pro312 | Val313 | Gly314 | Asn315 | Lys316 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Val317 | Ile318 | Ser319 | Pro320 | Ser321 | Glu322 | Asp323 | Arg324 | Lys325 | Gln326 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| NVPIPEGDEEGNMELRQKFEKAKLGPVGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLG |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 124.00 | 10 | K |
| 2 | Mus musculus | 124.00 | 5 | protein kinase C, alpha |
| 3 | Homo sapiens | 122.00 | 11 | protein kinase C, alpha |
| 4 | synthetic construct | 122.00 | 1 | protein kinase C alpha |
| 5 | Rattus norvegicus | 121.00 | 4 | PREDICTED: similar to Protein kinase C alpha type |
| 6 | Oryctolagus cuniculus | 120.00 | 4 | KPCA_RABIT Protein kinase C alpha type (PKC-alpha) |
| 7 | Bos taurus | 120.00 | 4 | protein kinase C, alpha |
| 8 | Canis familiaris | 120.00 | 3 | PREDICTED: similar to Protein kinase C, alpha type |
| 9 | Monodelphis domestica | 112.00 | 3 | PREDICTED: similar to protein kinase C |
| 10 | Gallus gallus | 105.00 | 3 | protein kinase C, alpha |
| 11 | Xenopus tropicalis | 95.90 | 1 | hypothetical protein LOC780209 |
| 12 | Latimeria chalumnae | 95.50 | 2 | protein kinase C alpha |
| 13 | Xenopus laevis | 88.60 | 1 | protein kinase C, alpha |
| 14 | Protopterus dolloi | 83.20 | 2 | protein kinase C alpha |
| 15 | Takifugu rubripes | 73.90 | 1 | protein kinase C, alpha type |
| 16 | Danio rerio | 68.20 | 7 | protein kinase C, beta 1 |
| 17 | Scyliorhinus canicula | 67.00 | 2 | protein kinase C alpha |
| 18 | Tetraodon nigroviridis | 66.20 | 3 | unnamed protein product |
| 19 | Macaca mulatta | 60.50 | 9 | PREDICTED: protein kinase C, beta 1 isoform 5 |
| 20 | Petromyzon marinus | 55.80 | 1 | protein kinase C |
| 21 | Myxine glutinosa | 44.70 | 1 | protein kinase C |
| 22 | Bombyx mori | 38.50 | 1 | conventional protein kinase C |
| 23 | Branchiostoma lanceolatum | 38.10 | 1 | protein kinase C |
| 24 | Macaca fascicularis | 37.70 | 1 | KPCG_MACFA Protein kinase C gamma type (PKC-gamma) |
| 25 | Apis mellifera | 36.20 | 1 | PREDICTED: similar to Protein C kinase 53E CG6622- |
| 26 | Anopheles gambiae str. PEST | 35.00 | 1 | ENSANGP00000009078 |
| 27 | Drosophila melanogaster | 33.90 | 4 | Protein C kinase 53E CG6622-PA, isoform A |
| 28 | Aplysia californica | 33.90 | 1 | KPC1_APLCA Calcium-dependent protein kinase C (APL |
| 29 | Aedes aegypti | 33.50 | 1 | protein kinase c |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| Mus musculus | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| Homo sapiens | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||||||||||||||||||| |||#|||||||||||||||||||||||||||||| Sbjct 287 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| synthetic construct | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||||||||||||||||||| |||#|||||||||||||||||||||||||||||| Sbjct 287 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| Rattus norvegicus | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 ||||||||||||+||||||||||||| |||#|||||||||||||||||||||||||||||| Sbjct 287 NVPIPEGDEEGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| Oryctolagus cuniculus | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||+||+||||||||||||| |||#|||||||||||||||||||||||||||||| Sbjct 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| Bos taurus | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 ||||||||||||+||||||||||||| |||#||||||||+||||||||||||||||||||| Sbjct 287 NVPIPEGDEEGNVELRQKFEKAKLGPAGNK#VISPSEDRRQPSNNLDRVKLTDFNFLMVLG 346 |
| Canis familiaris | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 ||||||||||||+||||||||||||| |||#||||||||+||||||||||||||||||||| Sbjct 205 NVPIPEGDEEGNVELRQKFEKAKLGPAGNK#VISPSEDRRQPSNNLDRVKLTDFNFLMVLG 264 |
| Monodelphis domestica | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 ||||||||||||||||||||||||||||||#||| |+||| |+|||||||||||||||||| Sbjct 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISSSDDRK-PTNNLDRVKLTDFNFLMVLG 345 |
| Gallus gallus | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 344 |||||+ ||+|| ||||||||||||| |||#||+||||| |||||||||||||||||| Sbjct 287 NVPIPDADEDGNAELRQKFEKAKLGPAGNK#VITPSEDRNSSVPSNNLDRVKLTDFNFLMV 346 Query 345 LG 346 || Query 345 LG 346 |
| Xenopus tropicalis | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 344 |||||| +++||+||||||||||||| |||#||||+++|+ ||||+| |+||||+|||| Sbjct 291 NVPIPEEEDDGNIELRQKFEKAKLGPAGNK#VISPTDERRPYVPSNNIDSVRLTDFSFLMV 350 Query 345 LG 346 || Query 345 LG 346 |
| Latimeria chalumnae | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 344 |||| | |+ ||+||||||||||||| |+|#|||| |+|| |||||||||||||||||| Sbjct 209 NVPISEADD-GNVELRQKFEKAKLGPAGSK#VISPVEERKSSTPSNNLDRVKLTDFNFLMV 267 Query 345 LG 346 || Query 345 LG 346 |
| Xenopus laevis | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 344 |||||| |+ ||+||||||||||||| |||#||+|+ +|+ ||||+| ++|||| |||| Sbjct 291 NVPIPEADD-GNLELRQKFEKAKLGPAGNK#VINPTGERRPYIPSNNIDSIRLTDFCFLMV 349 Query 345 LG 346 || Query 345 LG 346 |
| Protopterus dolloi | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||+ |+ ||+ ||||||||+||| | |#|||| | ||||| || ||||+|||| Sbjct 207 NVPIPDADD-GNVGLRQKFEKARLGPAGKK#VISPERKSSLPLNNLDRFKLEDFNFVMVLG 265 |
| Takifugu rubripes | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRK--QPSNNLDRVKLTDFNFLMV 344 |||||| |+ |+|||||||||||| | |#||+||+ |+ || |+|||+| ||||| + Sbjct 285 NVPIPEVDDV-NLELRQKFEKAKLGQ-GKK#VITPSDHRRFSLPSGNMDRVRLNDFNFLAL 342 Query 345 LG 346 || Query 345 LG 346 |
| Danio rerio | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSN-NLDRVKLTDFNFLMVL 345 |||+| |||| |||||||+||+|| # | + | || | ||+||+|||||||| Sbjct 286 NVPVPPEGEEGNEELRQKFERAKIGPSKTD#GSSSNAISKFDSNGNRDRMKLSDFNFLMVL 345 Query 346 G 346 | Query 346 G 346 |
| Scyliorhinus canicula | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||| | ||+ |||+||||||||| | |# | + |+|+|| | | ||||||||| Sbjct 220 NVPIIEDDEDS--ELRKKFEKAKLGPAGKK#AI--EKKPSSPTNDLDHVHLEDFNFLMVLG 275 |
| Tetraodon nigroviridis | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK--#VISPSEDRKQPSNNLDRVKLTDFNFLMV 344 |||+| |||| |||||||+||+|| | # + + | + | ||+|| ||||||| Sbjct 223 NVPVPPEGEEGNEELRQKFERAKIGPGKNTDG#KSANAASRFDSNGNQDRMKLADFNFLMV 282 Query 345 LG 346 || Query 345 LG 346 |
| Macaca mulatta | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#V----ISPSEDRKQPSNNLDRVKLTDFNFL 342 |||+| ||| |||||||+||+ | |#| + + + + | ||+|||||||| Sbjct 287 NVPVPPEGSEGNEELRQKFERAKISQ-GTK#VPEEKTTNTVSKFDNNGNRDRMKLTDFNFL 345 Query 343 MVLG 346 |||| Query 343 MVLG 346 |
| Petromyzon marinus | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISP--SEDRKQPS-------NNLDRVKLT 337 |||| |+|+ |+|+|||||+||| # + | |++|+ | |+|||| Sbjct 217 NVPIAPDIEDGDTEMRRKFEKARLGP----#SVKPRASDERRANSLSAILNNANVDRVKAD 272 Query 338 DFNFLMVLG 346 ||||||||| Query 338 DFNFLMVLG 346 |
| Myxine glutinosa | Query 287 NVPI-PEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPS---NNLDRVKLTDFNFL 342 |||+ |||+| +||||+ +++++ # ||++|+ | + |||| | || || Sbjct 208 NVPVAPEGEE--GLELRQRLQRSQIARSDKN#KQSPAKDQPSDSASLSGLDRVNLEDFVFL 265 Query 343 MVLG 346 ||| Sbjct 266 TVLG 269 |
| Bombyx mori | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSN--NLDRVKLTDFNFLMV 344 |||+|| || +| | + + || +# | ||+ | | | ++ |||||+|| Sbjct 290 NVPVPE---EG-ADLVQLKNQMRATTVGAR#RPPPPPDREVPHNVAAADVIRATDFNFIMV 345 Query 345 LG 346 || Query 345 LG 346 |
| Branchiostoma lanceolatum | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSN--------NLDRVKLTD 338 |||| + +|| +|++ +| || # | ||| | +|| +| | Sbjct 218 NVPIAD-EEENVAKLKEHLQKQKL------#----DEQRKQKSKRSEECNIGSLDHMKAAD 266 Query 339 FNFLMVLG 346 |||||||| Query 339 FNFLMVLG 346 |
| Macaca fascicularis | Query 287 NVPIPEGDEEGNMELRQKFE----------KAKLGPVGNK#VISPSEDRKQPSN-----NL 331 |||+ + | | | |||| + ++|| + #+ ||| | + Sbjct 287 NVPVADAD---NCSLLQKFEACNYPLELYERVRMGPSSSP#IPSPSPSPTDPKRCFFGASP 343 Query 332 DRVKLTDFNFLMVLG 346 |+ ++||+|||||| Sbjct 344 GRLHISDFSFLMVLG 358 |
| Apis mellifera | Query 287 NVPIPE-GDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSN--NLDRVKLTDFNFLM 343 |||+|| | + ++++ +| + |# + ++|++ | | | ++ +|||||| Sbjct 304 NVPVPEEGVDLAELKMKPSPQKTSV----TK#KTTTTQDKEVPHNMGKSDLIRASDFNFLM 359 Query 344 VLG 346 ||| Query 344 VLG 346 |
| Anopheles gambiae str. PEST | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSN--NLDRVKLTDFNFLMV 344 |||+|| + ++|+ + | + |# | |+ | | | ++ |||||||| Sbjct 227 NVPVPEEGAD-LVQLKSQMRKTSI----TK#KIPMMGDKDVPHNMTKKDVIRATDFNFLMV 281 Query 345 LG 346 || Query 345 LG 346 |
| Drosophila melanogaster | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 ||| + ||+ ++|+|| + | #++ |+ |+ | ++ |||||+ ||| Sbjct 296 NVPCAD-DEQDLLKLKQKPSQKK------P#MVMRSDTNTHTSSKKDMIRATDFNFIKVLG 348 |
| Aplysia californica | Query 288 VPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 ||+ + | |++ | ++ + ++# | |+ | + | |+ +||||| ||| Sbjct 272 VPVTDDITESIQEIKSKMHRSS---ISSE#KRYPEPDKVQNMSKQDIVRASDFNFLTVLG 327 |
| Aedes aegypti | Query 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||+|| || ++ | + | # + +| | ++ |||||||||| Sbjct 235 NVPVPE---EGTDLVQLKSQMRKTSISKKA#PVLCDKDVPHNMGKKDVIRATDFNFLMVLG 291 |
[Site 2] ELRQKFEKAK309-LGPVGNKVIS
Lys309 Leu
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Glu300 | Leu301 | Arg302 | Gln303 | Lys304 | Phe305 | Glu306 | Lys307 | Ala308 | Lys309 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Leu310 | Gly311 | Pro312 | Val313 | Gly314 | Asn315 | Lys316 | Val317 | Ile318 | Ser319 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| QEEGEYYNVPIPEGDEEGNMELRQKFEKAKLGPVGNKVISPSEDRKQPSNNLDRVKLTDF |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 126.00 | 12 | K |
| 2 | Mus musculus | 126.00 | 6 | protein kinase C, alpha |
| 3 | Homo sapiens | 124.00 | 11 | protein kinase C, alpha |
| 4 | synthetic construct | 124.00 | 1 | protein kinase C alpha |
| 5 | Rattus norvegicus | 123.00 | 4 | PREDICTED: similar to Protein kinase C alpha type |
| 6 | Oryctolagus cuniculus | 122.00 | 4 | KPCA_RABIT Protein kinase C alpha type (PKC-alpha) |
| 7 | Bos taurus | 122.00 | 4 | protein kinase C, alpha |
| 8 | Canis familiaris | 122.00 | 3 | PREDICTED: similar to Protein kinase C, alpha type |
| 9 | Monodelphis domestica | 114.00 | 3 | PREDICTED: similar to protein kinase C |
| 10 | Gallus gallus | 107.00 | 3 | protein kinase C, alpha |
| 11 | Xenopus tropicalis | 99.80 | 1 | hypothetical protein LOC780209 |
| 12 | Latimeria chalumnae | 97.40 | 2 | protein kinase C alpha |
| 13 | Xenopus laevis | 94.00 | 1 | protein kinase C, alpha |
| 14 | Protopterus dolloi | 86.30 | 2 | protein kinase C alpha |
| 15 | Takifugu rubripes | 79.30 | 1 | protein kinase C, alpha type |
| 16 | Scyliorhinus canicula | 68.90 | 2 | protein kinase C alpha |
| 17 | Danio rerio | 68.60 | 7 | protein kinase C, beta 1 |
| 18 | Tetraodon nigroviridis | 66.60 | 3 | unnamed protein product |
| 19 | Macaca mulatta | 60.80 | 9 | PREDICTED: protein kinase C, beta 1 isoform 5 |
| 20 | Petromyzon marinus | 57.80 | 1 | protein kinase C |
| 21 | Myxine glutinosa | 52.40 | 1 | protein kinase C |
| 22 | Macaca fascicularis | 41.60 | 1 | KPCG_MACFA Protein kinase C gamma type (PKC-gamma) |
| 23 | Branchiostoma lanceolatum | 40.00 | 1 | protein kinase C |
| 24 | Bombyx mori | 39.70 | 1 | conventional protein kinase C |
| 25 | Apis mellifera | 38.10 | 1 | PREDICTED: similar to Protein C kinase 53E CG6622- |
| 26 | Drosophila melanogaster | 37.70 | 4 | Protein C kinase 53E CG6622-PA, isoform A |
| 27 | Anopheles gambiae str. PEST | 37.00 | 1 | ENSANGP00000009078 |
| 28 | Aplysia californica | 36.60 | 1 | KPC1_APLCA Calcium-dependent protein kinase C (APL |
| 29 | Aedes aegypti | 35.40 | 1 | protein kinase c |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| Mus musculus | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| Homo sapiens | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||||||||||||||||#||| |||||||||||||||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| synthetic construct | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||||||||||||||||#||| |||||||||||||||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| Rattus norvegicus | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 |||||||||||||||||||+||||||||||#||| |||||||||||||||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| Oryctolagus cuniculus | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||+||+||||||||||#||| |||||||||||||||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| Bos taurus | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 |||||||||||||||||||+||||||||||#||| |||||||||||+|||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNVELRQKFEKAK#LGPAGNKVISPSEDRRQPSNNLDRVKLTDF 339 |
| Canis familiaris | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 |||||||||||||||||||+||||||||||#||| |||||||||||+|||||||||||||| Sbjct 198 QEEGEYYNVPIPEGDEEGNVELRQKFEKAK#LGPAGNKVISPSEDRRQPSNNLDRVKLTDF 257 |
| Monodelphis domestica | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||||||||||||||||#|||||||||| |+||| |+||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISSSDDRK-PTNNLDRVKLTDF 338 |
| Gallus gallus | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQ--PSNNLDRVKLT 337 ||||||||||||+ ||+|| ||||||||||#||| |||||+||||| ||||||||||| Sbjct 280 QEEGEYYNVPIPDADEDGNAELRQKFEKAK#LGPAGNKVITPSEDRNSSVPSNNLDRVKLT 339 Query 338 DF 339 || Query 338 DF 339 |
| Xenopus tropicalis | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQ--PSNNLDRVKLT 337 ||||||||||||| +++||+||||||||||#||| |||||||+++|+ ||||+| |+|| Sbjct 284 QEEGEYYNVPIPEEEDDGNIELRQKFEKAK#LGPAGNKVISPTDERRPYVPSNNIDSVRLT 343 Query 338 DF 339 || Query 338 DF 339 |
| Latimeria chalumnae | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQ--PSNNLDRVKLT 337 ||||||||||| | |+ ||+||||||||||#||| |+||||| |+|| ||||||||||| Sbjct 202 QEEGEYYNVPISEADD-GNVELRQKFEKAK#LGPAGSKVISPVEERKSSTPSNNLDRVKLT 260 Query 338 DF 339 || Query 338 DF 339 |
| Xenopus laevis | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQ--PSNNLDRVKLT 337 ||||||||||||| |+ ||+||||||||||#||| |||||+|+ +|+ ||||+| ++|| Sbjct 284 QEEGEYYNVPIPEADD-GNLELRQKFEKAK#LGPAGNKVINPTGERRPYIPSNNIDSIRLT 342 Query 338 DF 339 || Query 338 DF 339 |
| Protopterus dolloi | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||+ |+ ||+ ||||||||+#||| | ||||| | ||||| || || Sbjct 200 QEEGEYYNVPIPDADD-GNVGLRQKFEKAR#LGPAGKKVISPERKSSLPLNNLDRFKLEDF 258 |
| Takifugu rubripes | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRK--QPSNNLDRVKLT 337 ||||||||||||| |+ |+||||||||||#|| | |||+||+ |+ || |+|||+| Sbjct 278 QEEGEYYNVPIPEVDDV-NLELRQKFEKAK#LGQ-GKKVITPSDHRRFSLPSGNMDRVRLN 335 Query 338 DF 339 || Query 338 DF 339 |
| Scyliorhinus canicula | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||| | ||+ |||+||||||#||| | | | + |+|+|| | | || Sbjct 213 QEEGEYYNVPIIEDDEDS--ELRKKFEKAK#LGPAGKKAI--EKKPSSPTNDLDHVHLEDF 268 |
| Danio rerio | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSN-NLDRVKLTD 338 ||||||+|||+| |||| |||||||+||#+|| | + | || | ||+||+| Sbjct 279 QEEGEYFNVPVPPEGEEGNEELRQKFERAK#IGPSKTDGSSSNAISKFDSNGNRDRMKLSD 338 Query 339 F 339 | Query 339 F 339 |
| Tetraodon nigroviridis | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNK--VISPSEDRKQPSNNLDRVKLT 337 ||||||+|||+| |||| |||||||+||#+|| | + + | + | ||+|| Sbjct 216 QEEGEYFNVPVPPEGEEGNEELRQKFERAK#IGPGKNTDGKSANAASRFDSNGNQDRMKLA 275 Query 338 DF 339 || Query 338 DF 339 |
| Macaca mulatta | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKV----ISPSEDRKQPSNNLDRVK 335 ||||||+|||+| ||| |||||||+||#+ | || + + + + | ||+| Sbjct 280 QEEGEYFNVPVPPEGSEGNEELRQKFERAK#ISQ-GTKVPEEKTTNTVSKFDNNGNRDRMK 338 Query 336 LTDF 339 |||| Query 336 LTDF 339 |
| Petromyzon marinus | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISP--SEDRKQPS-------NN 330 ||||||||||| |+|+ |+|+|||||+#||| + | |++|+ | | Sbjct 210 QEEGEYYNVPIAPDIEDGDTEMRRKFEKAR#LGP----SVKPRASDERRANSLSAILNNAN 265 Query 331 LDRVKLTDF 339 +|||| || Sbjct 266 VDRVKADDF 274 |
| Myxine glutinosa | Query 280 QEEGEYYNVPI-PEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPS---NNLDRVK 335 ||||||||||+ |||+| +||||+ ++++#+ ||++|+ | + |||| Sbjct 201 QEEGEYYNVPVAPEGEE--GLELRQRLQRSQ#IARSDKNKQSPAKDQPSDSASLSGLDRVN 258 Query 336 LTDF 339 | || Sbjct 259 LEDF 262 |
| Macaca fascicularis | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKF----------EKAK#LGPVGNKVISPSEDRKQPSN 329 ||||||||||+ + | | | ||| |+ +#+|| + + ||| | Sbjct 280 QEEGEYYNVPVADAD---NCSLLQKFEACNYPLELYERVR#MGPSSSPIPSPSPSPTDPKR 336 Query 330 -----NLDRVKLTDF 339 + |+ ++|| Sbjct 337 CFFGASPGRLHISDF 351 |
| Branchiostoma lanceolatum | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPS--------NNL 331 ||||||||||| + +|| +|++ +| |#| | ||| | +| Sbjct 211 QEEGEYYNVPIAD-EEENVAKLKEHLQKQK#L----------DEQRKQKSKRSEECNIGSL 259 Query 332 DRVKLTDF 339 | +| || Sbjct 260 DHMKAADF 267 |
| Bombyx mori | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSN--NLDRVKLT 337 |||||+||||+| ||| +| | + +# || + | ||+ | | | ++ | Sbjct 283 QEEGEFYNVPVP---EEG-ADLVQLKNQMR#ATTVGARRPPPPPDREVPHNVAAADVIRAT 338 Query 338 DF 339 || Query 338 DF 339 |
| Apis mellifera | Query 280 QEEGEYYNVPIP-EGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSN--NLDRVKL 336 ||||||||||+| || + ++++ +| #+ | + ++|++ | | | ++ Sbjct 297 QEEGEYYNVPVPEEGVDLAELKMKPSPQKTS#V----TKKTTTTQDKEVPHNMGKSDLIRA 352 Query 337 TDF 339 +|| Sbjct 353 SDF 355 |
| Drosophila melanogaster | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 |+|||||||| + ||+ ++|+|| + |# ++ |+ |+ | ++ ||| Sbjct 289 QDEGEYYNVPCAD-DEQDLLKLKQKPSQKK#------PMVMRSDTNTHTSSKKDMIRATDF 341 |
| Anopheles gambiae str. PEST | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSN--NLDRVKLT 337 ||||||||||+|| + ++|+ + | #+ | | |+ | | | ++ | Sbjct 220 QEEGEYYNVPVPE-EGADLVQLKSQMRKTS#I----TKKIPMMGDKDVPHNMTKKDVIRAT 274 Query 338 DF 339 || Query 338 DF 339 |
| Aplysia californica | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 |||||+| ||+ + | |++ | ++ # + ++ | |+ | + | |+ +|| Sbjct 264 QEEGEFYGVPVTDDITESIQEIKSKMHRSS#---ISSEKRYPEPDKVQNMSKQDIVRASDF 320 |
| Aedes aegypti | Query 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||+| ||| ++ | + |# + +| | ++ ||| Sbjct 228 QEEGEYYNVPVP---EEGTDLVQLKSQMRK#TSISKKAPVLCDKDVPHNMGKKDVIRATDF 284 |
[Site 3] NKVISPSEDR324-KQPSNNLDRV
Arg324 Lys
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Asn315 | Lys316 | Val317 | Ile318 | Ser319 | Pro320 | Ser321 | Glu322 | Asp323 | Arg324 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Lys325 | Gln326 | Pro327 | Ser328 | Asn329 | Asn330 | Leu331 | Asp332 | Arg333 | Val334 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| EEGNMELRQKFEKAKLGPVGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVM |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 122.00 | 17 | K |
| 2 | Mus musculus | 122.00 | 12 | protein kinase C, alpha |
| 3 | Homo sapiens | 121.00 | 23 | aging-associated gene 6 protein |
| 4 | synthetic construct | 121.00 | 4 | protein kinase C alpha |
| 5 | Rattus norvegicus | 119.00 | 8 | PREDICTED: similar to Protein kinase C alpha type |
| 6 | Canis familiaris | 118.00 | 13 | PREDICTED: similar to Protein kinase C, alpha type |
| 7 | Bos taurus | 118.00 | 7 | protein kinase C, alpha |
| 8 | Oryctolagus cuniculus | 118.00 | 6 | KPCA_RABIT Protein kinase C alpha type (PKC-alpha) |
| 9 | Monodelphis domestica | 110.00 | 6 | PREDICTED: similar to protein kinase C |
| 10 | Gallus gallus | 107.00 | 7 | protein kinase C, alpha |
| 11 | Latimeria chalumnae | 104.00 | 2 | protein kinase C alpha |
| 12 | Xenopus tropicalis | 99.00 | 3 | hypothetical protein LOC780209 |
| 13 | Xenopus laevis | 94.70 | 2 | protein kinase C, alpha |
| 14 | Protopterus dolloi | 90.50 | 2 | protein kinase C alpha |
| 15 | Takifugu rubripes | 80.90 | 1 | protein kinase C, alpha type |
| 16 | Danio rerio | 75.10 | 14 | protein kinase C, beta 1 |
| 17 | Scyliorhinus canicula | 75.10 | 2 | protein kinase C alpha |
| 18 | Tetraodon nigroviridis | 73.20 | 5 | unnamed protein product |
| 19 | Macaca mulatta | 67.40 | 15 | PREDICTED: protein kinase C, beta isoform 1 |
| 20 | Petromyzon marinus | 65.90 | 1 | protein kinase C |
| 21 | Myxine glutinosa | 54.30 | 1 | protein kinase C |
| 22 | Bombyx mori | 49.30 | 1 | conventional protein kinase C |
| 23 | Branchiostoma lanceolatum | 49.30 | 1 | protein kinase C |
| 24 | Macaca fascicularis | 48.90 | 4 | KPCG_MACFA Protein kinase C gamma type (PKC-gamma) |
| 25 | Aplysia californica | 47.00 | 2 | KPC2_APLCA Calcium-independent protein kinase C (A |
| 26 | Anopheles gambiae str. PEST | 45.40 | 3 | ENSANGP00000009078 |
| 27 | Apis mellifera | 45.40 | 2 | PREDICTED: similar to Protein C kinase 53E CG6622- |
| 28 | Drosophila melanogaster | 44.30 | 8 | Protein C kinase 53E CG6622-PA, isoform A |
| 29 | Aedes aegypti | 44.30 | 2 | protein kinase c |
| 30 | Tribolium castaneum | 43.50 | 3 | PREDICTED: similar to CG6622-PA, isoform A |
| 31 | Magnaporthe grisea 70-15 | 41.20 | 1 | hypothetical protein MGG_08689 |
| 32 | Caenorhabditis briggsae | 41.20 | 1 | Hypothetical protein CBG16150 |
| 33 | Magnaporthe grisea | 40.80 | 1 | AF136600_1 protein kinase C |
| 34 | Coprinopsis cinerea okayama7#130 | 40.80 | 1 | hypothetical protein CC1G_07190 |
| 35 | Caenorhabditis elegans | 40.40 | 5 | Protein Kinase C family member (pkc-2) |
| 36 | Strongylocentrotus purpuratus | 40.40 | 4 | PREDICTED: similar to protein kinase C |
| 37 | Drosophila pseudoobscura | 40.00 | 3 | GA19732-PA |
| 38 | Paramecium tetraurelia | 40.00 | 1 | hypothetical protein |
| 39 | Schizosaccharomyces pombe | 39.30 | 3 | SPAC17G8.14c |
| 40 | Schizosaccharomyces pombe 972h- | 39.30 | 2 | hypothetical protein SPAC17G8.14c |
| 41 | Hydractinia echinata | 39.30 | 1 | putative calcium dependent protein kinase C |
| 42 | Pan troglodytes | 38.50 | 4 | PREDICTED: serum/glucocorticoid regulated kinase 3 |
| 43 | Tuber excavatum | 38.50 | 2 | protein kinase C-like protein |
| 44 | Yarrowia lipolytica | 38.50 | 1 | hypothetical protein |
| 45 | Botryotinia fuckeliana | 38.50 | 1 | protein kinase C |
| 46 | Calliphora vicina | 38.50 | 1 | eye-specific protein kinase C |
| 47 | Asparagus officinalis | 38.50 | 1 | S6 ribosomal protein kinase |
| 48 | Tuber aestivum | 38.10 | 2 | protein kinase C-like protein |
| 49 | Suberites domuncula | 38.10 | 2 | Serine/Threonine protein kinase |
| 50 | Aspergillus oryzae | 38.10 | 1 | unnamed protein product |
| 51 | Cryptococcus neoformans var. grubii | 38.10 | 1 | protein kinase C 1 |
| 52 | Cochliobolus heterostrophus | 38.10 | 1 | KPC1_COCHE Protein kinase C-like emb |
| 53 | Sycon raphanus | 38.10 | 1 | Serine/Threonine protein kinase |
| 54 | Cryptococcus neoformans var. neoformans B-3501A | 37.70 | 1 | hypothetical protein CNBC3910 |
| 55 | Squalus acanthias | 37.70 | 1 | s-sgk1 |
| 56 | Leptosphaeria maculans | 37.70 | 1 | AF487263_9 protein kinase C |
| 57 | Cryptococcus neoformans var. neoformans JEC21 | 37.70 | 1 | protein kinase C |
| 58 | Aspergillus terreus NIH2624 | 37.70 | 1 | hypothetical protein ATEG_02078 |
| 59 | Cryptococcus neoformans var. neoformans | 37.70 | 1 | protein kinase C 1 |
| 60 | Leishmania braziliensis | 37.40 | 1 | zinc finger protein kinase-like |
| 61 | Aspergillus clavatus NRRL 1 | 37.40 | 1 | protein kinase c |
| 62 | Plasmodium berghei strain ANKA | 37.40 | 1 | rac-beta serine/threonine protein kinase |
| 63 | Tuber indicum | 37.00 | 6 | protein kinase C-like protein |
| 64 | Phaeosphaeria nodorum SN15 | 37.00 | 2 | hypothetical protein SNOG_13609 |
| 65 | Tuber pseudoexcavatum | 37.00 | 2 | protein kinase C-like protein |
| 66 | Neosartorya fischeri NRRL 181 | 37.00 | 1 | protein kinase c |
| 67 | Sporothrix schenckii | 36.60 | 1 | AF124792_1 protein kinase C; serine/threonine prot |
| 68 | Debaryomyces hansenii CBS767 | 36.60 | 1 | hypothetical protein DEHA0G14773g |
| 69 | Hydra vulgaris | 36.20 | 2 | protein kinase C |
| 70 | Plasmodium yoelii yoelii str. 17XNL | 36.20 | 1 | hypothetical protein PY00403 |
| 71 | Coccidioides immitis RS | 36.20 | 1 | hypothetical protein CIMG_09206 |
| 72 | Candida albicans | 36.20 | 1 | KPC1_CANAL Protein kinase C-like 1 (PKC 1) emb |
| 73 | Ashbya gossypii ATCC 10895 | 36.20 | 1 | ACR191Cp |
| 74 | Blumeria graminis | 35.80 | 1 | AF247001_1 protein kinase C |
| 75 | Fundulus heteroclitus | 35.80 | 1 | serum and glucocorticoid-regulated kinase |
| 76 | Neurospora crassa | 35.80 | 1 | protein kinase C homologue |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Mus musculus | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Homo sapiens | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |||||||||||||||||| |||||||||||#|||||||||||||||||||||||||||||| Sbjct 295 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| synthetic construct | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |||||||||||||||||| |||||||||||#|||||||||||||||||||||||||||||| Sbjct 295 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Rattus norvegicus | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ||||+||||||||||||| |||||||||||#|||||||||||||||||||||||||||||| Sbjct 295 EEGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Canis familiaris | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ||||+||||||||||||| |||||||||||#+||||||||||||||||||||||||||||| Sbjct 213 EEGNVELRQKFEKAKLGPAGNKVISPSEDR#RQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 272 |
| Bos taurus | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ||||+||||||||||||| |||||||||||#+||||||||||||||||||||||||||||| Sbjct 295 EEGNVELRQKFEKAKLGPAGNKVISPSEDR#RQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Oryctolagus cuniculus | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+||+||||||||||||| |||||||||||#|||||||||||||||||||||||||||||| Sbjct 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Monodelphis domestica | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ||||||||||||||||||||||||| |+||#| |+|||||||||||||||||||||||||| Sbjct 295 EEGNMELRQKFEKAKLGPVGNKVISSSDDR#K-PTNNLDRVKLTDFNFLMVLGKGSFGKVM 353 |
| Gallus gallus | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 352 |+|| ||||||||||||| |||||+|||||# |||||||||||||||||||||||||| Sbjct 295 EDGNAELRQKFEKAKLGPAGNKVITPSEDR#NSSVPSNNLDRVKLTDFNFLMVLGKGSFGK 354 Query 353 VM 354 || Query 353 VM 354 |
| Latimeria chalumnae | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 352 ++||+||||||||||||| |+||||| |+|#| |||||||||||||||||||||||||| Sbjct 216 DDGNVELRQKFEKAKLGPAGSKVISPVEER#KSSTPSNNLDRVKLTDFNFLMVLGKGSFGK 275 Query 353 VM 354 || Query 353 VM 354 |
| Xenopus tropicalis | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 352 ++||+||||||||||||| |||||||+++|#+ ||||+| |+||||+|||||||||||| Sbjct 299 DDGNIELRQKFEKAKLGPAGNKVISPTDER#RPYVPSNNIDSVRLTDFSFLMVLGKGSFGK 358 Query 353 VM 354 || Query 353 VM 354 |
| Xenopus laevis | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 352 ++||+||||||||||||| |||||+|+ +|#+ ||||+| ++|||| |||||||||||| Sbjct 298 DDGNLELRQKFEKAKLGPAGNKVINPTGER#RPYIPSNNIDSIRLTDFCFLMVLGKGSFGK 357 Query 353 VM 354 || Query 353 VM 354 |
| Protopterus dolloi | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ++||+ ||||||||+||| | ||||| # | ||||| || ||||+|||||||||||| Sbjct 214 DDGNVGLRQKFEKARLGPAGKKVISPERKS#SLPLNNLDRFKLEDFNFVMVLGKGSFGKVM 273 |
| Takifugu rubripes | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#K--QPSNNLDRVKLTDFNFLMVLGKGSFGK 352 ++ |+|||||||||||| | |||+||+ |#+ || |+|||+| ||||| +|||||||| Sbjct 292 DDVNLELRQKFEKAKLGQ-GKKVITPSDHR#RFSLPSGNMDRVRLNDFNFLALLGKGSFGK 350 Query 353 VM 354 || Query 353 VM 354 |
| Danio rerio | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSN-NLDRVKLTDFNFLMVLGKGSFGKV 353 |||| |||||||+||+|| | + #| || | ||+||+|||||||||||||||| Sbjct 294 EEGNEELRQKFERAKIGPSKTDGSSSNAIS#KFDSNGNRDRMKLSDFNFLMVLGKGSFGKV 353 Query 354 M 354 | Query 354 M 354 |
| Scyliorhinus canicula | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ++ + |||+||||||||| | | | # |+|+|| | | ||||||||||||||||| Sbjct 226 DDEDSELRKKFEKAKLGPAGKKAIEKKPS-#-SPTNDLDHVHLEDFNFLMVLGKGSFGKVM 283 |
| Tetraodon nigroviridis | Query 295 EEGNMELRQKFEKAKLGPVGNK--VISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGK 352 |||| |||||||+||+|| | + + |# + | ||+|| ||||||||||||||| Sbjct 231 EEGNEELRQKFERAKIGPGKNTDGKSANAASR#FDSNGNQDRMKLADFNFLMVLGKGSFGK 290 Query 353 VM 354 || Query 353 VM 354 |
| Macaca mulatta | Query 296 EGNMELRQKFEKAKLGPVGNKVISPSE------DR#KQPSNNLDRVKLTDFNFLMVLGKGS 349 ||| |||||||+||+ | || | | +# + | ||+||||||||||||||| Sbjct 296 EGNEELRQKFERAKISQ-GTKV--PEEKTTNTVSK#FDNNGNRDRMKLTDFNFLMVLGKGS 352 Query 350 FGKVM 354 ||||| Query 350 FGKVM 354 |
| Petromyzon marinus | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSN---------NLDRVKLTDFNFLMVL 345 |+|+ |+|+|||||+||| + | #++ +| |+|||| |||||||| Sbjct 225 EDGDTEMRRKFEKARLGPS----VKPRASD#ERRANSLSAILNNANVDRVKADDFNFLMVL 280 Query 346 GKGSFGKVM 354 ||||||||| Query 346 GKGSFGKVM 354 |
| Myxine glutinosa | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPS---NNLDRVKLTDFNFLMVLGKGSFG 351 ||| +||||+ +++++ ||++|+# | + |||| | || || |||||||| Sbjct 216 EEG-LELRQRLQRSQIARSDKNKQSPAKDQ#PSDSASLSGLDRVNLEDFVFLTVLGKGSFG 274 Query 352 KVM 354 ||| Query 352 KVM 354 |
| Bombyx mori | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSFGK 352 ||| +| | + + || + | ||#+ | | | ++ |||||+|||||||||| Sbjct 295 EEG-ADLVQLKNQMRATTVGARRPPPPPDR#EVPHNVAAADVIRATDFNFIMVLGKGSFGK 353 Query 353 VM 354 || Query 353 VM 354 |
| Branchiostoma lanceolatum | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSN--------NLDRVKLTDFNFLMVLG 346 || +|++ +| || | |#|| | +|| +| ||||||||| Sbjct 225 EENVAKLKEHLQKQKL----------DEQR#KQKSKRSEECNIGSLDHMKAADFNFLMVLG 274 Query 347 KGSFGKVM 354 |||||||| Query 347 KGSFGKVM 354 |
| Macaca fascicularis | Query 305 FEKAKLGPVGNKVISPSEDR#KQPSN-----NLDRVKLTDFNFLMVLGKGSFGKVM 354 +|+ ++|| + + ||| # | + |+ ++||+|||||||||||||| Sbjct 312 YERVRMGPSSSPIPSPSPSP#TDPKRCFFGASPGRLHISDFSFLMVLGKGSFGKVM 366 |
| Aplysia californica | Query 314 GNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |++ ||| ||# + ++ |+ | ||||+ ||||||||||| Sbjct 380 GSRTRSPSSDR#SRSHHS--RISLHDFNFIKVLGKGSFGKVM 418 |
| Anopheles gambiae str. PEST | Query 295 EEGN--MELRQKFEKAKLGPVGNKVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSF 350 ||| ++|+ + | + | | |+# | | | ++ |||||||||||||| Sbjct 232 EEGADLVQLKSQMRKTSI----TKKIPMMGDK#DVPHNMTKKDVIRATDFNFLMVLGKGSF 287 Query 351 GKVM 354 |||| Query 351 GKVM 354 |
| Apis mellifera | Query 316 KVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSFGKVM 354 | + ++|+#+ | | | ++ +||||||||||||||||| Sbjct 330 KKTTTTQDK#EVPHNMGKSDLIRASDFNFLMVLGKGSFGKVM 370 |
| Drosophila melanogaster | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ ++|+|| + | ++ |+ # |+ | ++ |||||+ ||||||||||+ Sbjct 303 EQDLLKLKQKPSQKK------PMVMRSDTN#THTSSKKDMIRATDFNFIKVLGKGSFGKVL 356 |
| Aedes aegypti | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ||| ++ | + | + +| # | ++ |||||||||||||||||| Sbjct 240 EEGTDLVQLKSQMRKTSISKKAPVLCDKDV#PHNMGKKDVIRATDFNFLMVLGKGSFGKVM 299 |
| Tribolium castaneum | Query 313 VGNKVISPSEDR#KQPSNN--LDRVKLTDFNFLMVLGKGSFGKVM 354 | |+ + +#++|| + | ++ +||||||||||||||||| Sbjct 309 VNNQEAVDHDRQ#RRPSQHGQKDIIRASDFNFLMVLGKGSFGKVM 352 |
| Magnaporthe grisea 70-15 | Query 302 RQKFEKAKLGPVGNKVISPSEDR#KQPS----NNLDRVKLTDFNFLMVLGKGSFGKVM 354 +| |+ + | || | |# || |+ | |||| |||||+||||| Sbjct 816 QQHQEQQIISPTAGTVIPTSAKR#PLPSATDPGTGQRIGLDHFNFLAVLGKGNFGKVM 872 |
| Caenorhabditis briggsae | Query 328 SNNLDRVKLTDFNFLMVLGKGSFGKVM 354 + | | +| +||||| ||||||||||+ Sbjct 404 NTNRDVIKASDFNFLTVLGKGSFGKVL 430 |
| Magnaporthe grisea | Query 302 RQKFEKAKLGPVGNKVISPSEDR#KQPS----NNLDRVKLTDFNFLMVLGKGSFGKVM 354 +| |+ + | || | |# || |+ | |||| |||||+||||| Sbjct 816 QQHQEQQIISPTAGTVIPTSARR#PLPSATDPGTGQRIGLDHFNFLAVLGKGNFGKVM 872 |
| Coprinopsis cinerea okayama7#130 | Query 306 EKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ++ + | + + ++ +#+||| +| | ||||| |||||+||||| Sbjct 685 QQGMVPPQHQQQMIQAQPQ#RQPSKKR-KVGLDDFNFLAVLGKGNFGKVM 732 |
| Caenorhabditis elegans | Query 328 SNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+| + +| +||||| ||||||||||+ Sbjct 337 SSNHNVIKASDFNFLTVLGKGSFGKVL 363 |
| Strongylocentrotus purpuratus | Query 321 SEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | # ++++ |+ +||||| ||||||||||| Sbjct 307 SSQN#SNSNSSMGLVRASDFNFLSVLGKGSFGKVM 340 |
| Drosophila pseudoobscura | Query 303 QKFEKAKLGPVGNKVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSFGKVM 354 | | | | | + | # |+ | ++ |||||+ ||||||||||+ Sbjct 190 QDLLKLKQKPSQKKPLVMRSDT#NTHSSISKKDMIRATDFNFIKVLGKGSFGKVL 243 |
| Paramecium tetraurelia | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 +|| ++ +| || ++ | # | |||||| | |||+||||||| Sbjct 32 KEGEQQMNDEFMKAPTATF-EQIEETGEQV#FVDDNREAIVKLTDFQFEKVLGRGSFGKVM 90 |
| Schizosaccharomyces pombe | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | |#++ | || | || || |||||+||||| Sbjct 556 PESPR#REKKN---RVTLDDFTFLAVLGKGNFGKVM 587 |
| Schizosaccharomyces pombe 972h- | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | |#++ | || | || || |||||+||||| Sbjct 648 PESPR#REKKN---RVTLDDFTFLAVLGKGNFGKVM 679 |
| Hydractinia echinata | Query 332 DRVKLTDFNFLMVLGKGSFGKVM 354 +|+|| || || |+||||||||| Sbjct 191 ERLKLEDFTFLKVIGKGSFGKVM 213 |
| Pan troglodytes | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | + +| + ||| || | # |||+|| |+||||||||+ Sbjct 134 ERSSQKLHSTSQNINLGPSGNPHAKP----#------------TDFDFLKVIGKGSFGKVL 177 |
| Tuber excavatum | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ + #+|| ++ | |||| |||||+||||| Sbjct 312 PAPEP#QQPVIRPAKIGLDHFNFLAVLGKGNFGKVM 346 |
| Yarrowia lipolytica | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 |+ | ||||| |||||+||||| Sbjct 919 RIGLDDFNFLAVLGKGNFGKVM 940 |
| Botryotinia fuckeliana | Query 312 PVGNKVISPSEDR#KQPSNNLD-----RVKLTDFNFLMVLGKGSFGKVM 354 | +|+ + |#|| | |+ | |||| |||||+||||| Sbjct 813 PGSQQVVPQGQQR#KQVPAANDAGTGRRIGLDHFNFLAVLGKGNFGKVM 860 |
| Calliphora vicina | Query 320 PSEDR#KQPSNNL---DRVKLTDFNFLMVLGKGSFGKVM 354 | | #| +|+ | ++ ||||+ ||||||+||++ Sbjct 333 PRIDN#KDMPHNMSKRDMIRAADFNFIKVLGKGSYGKIL 370 |
| Asparagus officinalis | Query 321 SEDR#KQPSN-NLDRVKLTDFNFLMVLGKGSFGKV 353 +|+ #+ ||+ |++|| | ||+|| |+|+|+|||| Sbjct 106 AEEH#EVPSSENVERVGLEDFDFLKVVGQGAFGKV 139 |
| Tuber aestivum | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ + #+ | + ++ | |||| |||||+||||| Sbjct 314 PAPEP#QPPVSRPTKIGLDHFNFLAVLGKGNFGKVM 348 |
| Suberites domuncula | Query 328 SNNLDRVKLTDFNFLMVLGKGSFGKV 353 + ++ ++|| ||| |+|||||||||| Sbjct 332 AKDMPKMKLEDFNLLVVLGKGSFGKV 357 |
| Aspergillus oryzae | Query 312 PVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 || + ++ || # | |+ | |||| |||||+||||| Sbjct 741 PVMQQQVAMKEDA#P-PQQPKVRIGLDHFNFLAVLGKGNFGKVM 782 |
| Cryptococcus neoformans var. grubii | Query 312 PVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 || +| +#+ +| | ||||| |||||+||||| Sbjct 730 PVQQQVTQRLPPQ#QPVMTRKRKVGLDDFNFLAVLGKGNFGKVM 772 |
| Cochliobolus heterostrophus | Query 310 LGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 +| | | ++|+ + #+ |+ | |||| |||||+||||| Sbjct 823 VGEVPGKKVTPAANT#QGTGK---RIGLDHFNFLAVLGKGNFGKVM 864 |
| Sycon raphanus | Query 335 KLTDFNFLMVLGKGSFGKVM 354 ||+||+|| ||||||||||| Sbjct 362 KLSDFSFLKVLGKGSFGKVM 381 |
| Cryptococcus neoformans var. neoformans B-3501A | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 +| | ||||| |||||+||||| Sbjct 754 KVGLDDFNFLAVLGKGNFGKVM 775 |
| Squalus acanthias | Query 327 PSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ||+| + | +||||| |+||||||||+ Sbjct 89 PSSN-PQAKPSDFNFLKVIGKGSFGKVL 115 |
| Leptosphaeria maculans | Query 299 MELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLD----RVKLTDFNFLMVLGKGSFGKVM 354 | +| |++ | + |++# || | |+ | |||| |||||+||||| Sbjct 816 MSQKQPEAIAQIPPSKQLPPANPENK#VTPSANTQGSGKRIGLDHFNFLAVLGKGNFGKVM 875 |
| Cryptococcus neoformans var. neoformans JEC21 | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 +| | ||||| |||||+||||| Sbjct 751 KVGLDDFNFLAVLGKGNFGKVM 772 |
| Aspergillus terreus NIH2624 | Query 312 PVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 || + ++ |+ # | + |+ | |||| |||||+||||| Sbjct 747 PVMQQQVAVKEEV#PPPQPKV-RIGLDHFNFLAVLGKGNFGKVM 788 |
| Cryptococcus neoformans var. neoformans | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 +| | ||||| |||||+||||| Sbjct 751 KVGLDDFNFLAVLGKGNFGKVM 772 |
| Leishmania braziliensis | Query 295 EEGNMELRQKFEKAKLGPVG-NKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKV 353 || ++|+ |+ + ++|| # |+|| | | || | |+|+|+|||| Sbjct 590 EESGQVMQQQRVINSTSPIPYSSLLSPRGSL#VSRSDNLSPVGLQDFQLLTVIGRGTFGKV 649 Query 354 M 354 + Sbjct 650 L 650 |
| Aspergillus clavatus NRRL 1 | Query 312 PVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ +| | #+|| |+ | |||| |||||+||||| Sbjct 763 PMQQQVAVKEEVP#QQPKA---RIGLDHFNFLSVLGKGNFGKVM 802 |
| Plasmodium berghei strain ANKA | Query 298 NMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ + +||+| + | | | +#|+ |+| +|||| |+||||+|||+ Sbjct 259 NLYIHDMYEKSKKKRL-RKFIPLSNKK#KR------RIKPDNFNFLKVIGKGSYGKVL 308 |
| Tuber indicum | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ + #+| + ++ | |||| |||||+||||| Sbjct 313 PAPEP#QQVVSKPTKIGLDHFNFLAVLGKGNFGKVM 347 |
| Phaeosphaeria nodorum SN15 | Query 329 NNLDRVKLTDFNFLMVLGKGSFGKVM 354 | ||+ + || | |+||||||||| Sbjct 273 NRQDRLSIDDFELLKVVGKGSFGKVM 298 |
| Tuber pseudoexcavatum | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ + #+| + ++ | |||| |||||+||||| Sbjct 312 PAPEP#QQVVSKPTKIGLDHFNFLAVLGKGNFGKVM 346 |
| Neosartorya fischeri NRRL 181 | Query 297 GNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | + +|+ ++ + |+ +| | # | |+ | |||| |||||+||||| Sbjct 743 GMPQQQQQQQQQAVAPMQQQVAVKEEI-#-PPQQPKVRIGLDHFNFLAVLGKGNFGKVM 798 |
| Sporothrix schenckii | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 |+ | +|||| |||||+||||| Sbjct 863 RIGLDNFNFLAVLGKGNFGKVM 884 |
| Debaryomyces hansenii CBS767 | Query 326 QPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 +| ++ | || || |||||+||||| Sbjct 750 KPKRRRRKIGLDDFQFLAVLGKGNFGKVM 778 |
| Hydra vulgaris | Query 335 KLTDFNFLMVLGKGSFGKVM 354 || || || |+||||||||| Sbjct 338 KLEDFTFLKVIGKGSFGKVM 357 |
| Plasmodium yoelii yoelii str. 17XNL | Query 300 ELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ++ +| +| +| | | | +#|+ ||| +|||| |+||||+|||+ Sbjct 370 DMHEKSKKKRL----RKFIPLSNKK#KR------RVKPDNFNFLKVIGKGSYGKVL 414 |
| Coccidioides immitis RS | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 || | |||| |||||+||||| Sbjct 740 RVGLDHFNFLAVLGKGNFGKVM 761 |
| Candida albicans | Query 295 EEGNMELRQKFEKAKLGPVGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ++ | +++| ++ +|| | #|+ +| | || || |||||+||||| Sbjct 729 KQQNQQVQQVQQQEELGHQRTHSSGKSGKS#KRRKR---KVGLDDFQFLAVLGKGNFGKVM 785 |
| Ashbya gossypii ATCC 10895 | Query 299 MELRQKFEKAKLGPVGNKVISPSEDR-#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 || + | | | + + |+ | #|+ + +| | || | |||||+||||+ Sbjct 781 MESIPQHPPAPLSPPKAQPVQPASGRH#KRKTPKRRKVSLDDFILLKVLGKGNFGKVL 837 |
| Blumeria graminis | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 |+ | |||| |||||+||||| Sbjct 826 RIGLDHFNFLAVLGKGNFGKVM 847 |
| Fundulus heteroclitus | Query 319 SPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |||+ # ++ | +||+|| |+||||||||+ Sbjct 78 SPSQQI#NLGPSSNPSAKPSDFHFLKVIGKGSFGKVL 113 |
| Neurospora crassa | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 |+ | |||| |||||+||||| Sbjct 811 RIGLDHFNFLAVLGKGNFGKVM 832 |
* References
[PubMed ID: 2469625] Rose-John S, Dietrich A, Marks F, Molecular cloning of mouse protein kinase C (PKC) cDNA from Swiss 3T3 fibroblasts. Gene. 1988 Dec 30;74(2):465-71.
[PubMed ID: 2601739] ... Megidish T, Mazurek N, A mutant protein kinase C that can transform fibroblasts. Nature. 1989 Dec 14;342(6251):807-11.
[PubMed ID: 7844141] ... Staudinger J, Zhou J, Burgess R, Elledge SJ, Olson EN, PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system. J Cell Biol. 1995 Feb;128(3):263-71.
[PubMed ID: 17114649] ... Munton RP, Tweedie-Cullen R, Livingstone-Zatchej M, Weinandy F, Waidelich M, Longo D, Gehrig P, Potthast F, Rutishauser D, Gerrits B, Panse C, Schlapbach R, Mansuy IM, Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93. Epub 2006 Nov 17.