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XSB1338 : Chain A, Crystal Structure Of Caenorhabditis Elegans Mg-Atp Actin Complexed With Human Gelsolin Segment 1 At 1.75 A Resolution.

[ CaMP Format ]

This entry is computationally expanded from SB0031

* Basic Information

OrganismCaenorhabditis elegans
Protein NamesActin-1/3
Gene NamesT04C12.6
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
1D4X_A N/A N/A P10983 N/A N/A N/A cel:T04C12.6

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 375 aa

Average Mass: 41.665 kDa

Monoisotopic Mass: 41.638 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Actin 1. 2375836.41.7e-248
--- cleavage 37 (inside Actin 2..375) ---

3. Sequence Information

Fasta Sequence: XSB1338.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1D4X (X-ray; 175 A; A=2-376)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] RAVFPSIVGR37-PRHQGVMVGM

Arg37 Pro

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Arg28Ala29Val30Phe31Pro32Ser33Ile34Val35Gly36Arg37
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Pro38Arg39His40Gln41Gly42Val43Met44Val45Gly46Met47

Sequence conservation (by blast)

* References

[PubMed ID: 2395459] Kabsch W, Mannherz HG, Suck D, Pai EF, Holmes KC, Atomic structure of the actin:DNase I complex. Nature. 1990 Sep 6;347(6288):37-44.

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