logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1362 : actin 5C, isoform B [Drosophila melanogaster]

[ CaMP Format ]

This entry is computationally expanded from SB0031

* Basic Information

OrganismDrosophila melanogaster (fruit fly)
Protein NamesActin-5C; actin 5C; isoform B; CG4027-PB; Act5C-PB; F-actin; 5C actin; actin5C; anon-fast-evolving-2D2; actin A1
Gene NamesAct5C; CG4027; Actin 5C
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_511052 NM_078497 31521 P10987 N/A N/A N/A dme:Dmel_CG4027

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 376 aa

Average Mass: 41.822 kDa

Monoisotopic Mass: 41.795 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Actin 1. 3376830.31.2e-246
--- cleavage 38 (inside Actin 3..376) ---

3. Sequence Information

Fasta Sequence: XSB1362.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1N58 (Model; -; A=1-376), 2HF3 (X-ray; 180 A; A=3-376), 2HF4 (X-ray; 180 A; A=3-376), 3EKS (X-ray; 180 A; A=2-376), 3EKU (X-ray; 250 A; A=2-376), 3EL2 (X-ray; 250 A; A=2-376)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] RAVFPSIVGR38-PRHQGVMVGM

Arg38 Pro

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Arg29Ala30Val31Phe32Pro33Ser34Ile35Val36Gly37Arg38
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Pro39Arg40His41Gln42Gly43Val44Met45Val46Gly47Met48

Sequence conservation (by blast)

* References

[PubMed ID: 17569867] Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE, Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Science. 2007 Jun 15;316(5831):1625-8.

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