logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1474 : actin [Schizosaccharomyces pombe]

[ CaMP Format ]

This entry is computationally expanded from SB0031

* Basic Information

OrganismSchizosaccharomyces pombe (fission yeast)
Protein NamesActin; actin (PMID 10547441)
Gene Namesact1; SPBC32H8.12c, pi012; cps8
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_595618 NM_001021513 2540051 P10989 N/A N/A N/A spo:SPBC32H8.12c

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 375 aa

Average Mass: 41.765 kDa

Monoisotopic Mass: 41.738 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Actin 1. 2375795.43.9e-236
--- cleavage 37 (inside Actin 2..375) ---

3. Sequence Information

Fasta Sequence: XSB1474.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] RAVFPSIVGR37-PRHHGIMVGM

Arg37 Pro

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Arg28Ala29Val30Phe31Pro32Ser33Ile34Val35Gly36Arg37
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Pro38Arg39His40His41Gly42Ile43Met44Val45Gly46Met47

Sequence conservation (by blast)

* References

[PubMed ID: 11859360] Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Schafer M, Muller-Auer S, Gabel C, Fuchs M, Dusterhoft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dreano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, Sanchez M, del Rey F, Benito J, Dominguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, The genome sequence of Schizosaccharomyces pombe. Nature. 2002 Feb 21;415(6874):871-80.