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XSB1518 : actin, alpha 2, smooth muscle, aorta [Gallus gallus]

[ CaMP Format ]

This entry is computationally expanded from SB0071

* Basic Information

OrganismGallus gallus (chicken)
Protein NamesActin, aortic smooth muscle; Alpha-actin; actin; alpha 2; smooth muscle; aorta
Gene NamesACTA2; actin, alpha 2, smooth muscle, aorta
Gene Locus6; chromosome 6
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001026400 NM_001031229 423787 P08023 N/A N/A N/A gga:423787

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 377 aa

Average Mass: 41.995 kDa

Monoisotopic Mass: 41.968 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Actin 1. 4377836.22e-248
--- cleavage 39 (inside Actin 4..377) ---

3. Sequence Information

Fasta Sequence: XSB1518.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1LVT (Model; -; A=1-377)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] RAVFPSIVGR39-PRHQGVMVGM

Arg39 Pro

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Arg30Ala31Val32Phe33Pro34Ser35Ile36Val37Gly38Arg39
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Pro40Arg41His42Gln43Gly44Val45Met46Val47Gly48Met49

Sequence conservation (by blast)

* References

[PubMed ID: 18688635] Kurz H, Fehr J, Nitschke R, Burkhardt H, Pericytes in the mature chorioallantoic membrane capillary plexus contain desmin and alpha-smooth muscle actin: relevance for non-sprouting angiogenesis. Histochem Cell Biol. 2008 Nov;130(5):1027-40. Epub 2008 Aug 8.

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