XSB1634 : filamin A, alpha (actin binding protein 280) [Homo sapiens]
[ CaMP Format ]
This entry is computationally expanded from SB0090
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | Filamin A, alpha (Actin binding protein 280); filamin A; alpha (actin binding protein 280); SubName: Full=Filamin A; alpha; Actin binding protein 280 |
| Gene Names | FLNA; XX-FW83128A1.1-015 |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein |
Entrez Nucleotide |
Entrez Gene |
UniProt |
OMIM |
HGNC |
HPRD |
KEGG |
| CAI43201 |
N/A |
N/A |
Q5HY89 |
N/A |
N/A |
N/A |
hsa: |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 231 aa
Average Mass: 24.990 kDa
Monoisotopic Mass: 24.975 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| --- cleavage 51 --- |
| Filamin 1. | 55 | 139 | 38.8 | 2.2e-08 |
| Filamin 2. | 144 | 231 | 17.5 | 0.00034 |
3. Sequence Information
Fasta Sequence: XSB1634.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] QYTYAQGGQQ51-TWAPERPLVG
Gln51 
Thr
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Gln42 | Tyr43 | Thr44 | Tyr45 | Ala46 | Gln47 | Gly48 | Gly49 | Gln50 | Gln51 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Thr52 | Trp53 | Ala54 | Pro55 | Glu56 | Arg57 | Pro58 | Leu59 | Val60 | Gly61 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQTWAPERPLVGVNGLDVTSLRPFDLVIPFTI
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Homo sapiens |
125.00 |
17 |
filamin A, alpha (actin binding protein 280) |
| 2 |
Macaca mulatta |
124.00 |
5 |
PREDICTED: filamin 1 (actin-binding protein-280) i |
| 3 |
Canis familiaris |
117.00 |
13 |
PREDICTED: similar to Filamin A (Alpha-filamin) (F |
| 4 |
Bos taurus |
114.00 |
1 |
PREDICTED: similar to filamin |
| 5 |
Mus musculus |
112.00 |
12 |
filamin, alpha |
| 6 |
N/A |
112.00 |
2 |
F |
| 7 |
Rattus norvegicus |
107.00 |
3 |
PREDICTED: similar to Filamin-A (Alpha-filamin) (F |
| 8 |
Gallus gallus |
46.60 |
2 |
filamin |
| 9 |
Tetraodon nigroviridis |
43.90 |
2 |
unnamed protein product |
| 10 |
Pan troglodytes |
42.70 |
3 |
PREDICTED: filamin B, beta (actin binding protein |
| 11 |
Danio rerio |
42.40 |
1 |
PREDICTED: similar to gamma-filamin |
Top-ranked sequences
| organism | matching |
|---|
| Homo sapiens |
Query 22 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 22 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
|
| Macaca mulatta |
Query 22 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
||||||||||||||||||||||||||||||#|||||||||||||||+||||||||||||||
Sbjct 1705 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDMTSLRPFDLVIPFTI 1764
|
| Canis familiaris |
Query 22 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
|||||||+ ||||| ||||| |||||||||#||||||||+|||||||||||||||||||||
Sbjct 1740 ALAGDQPAAQPPLRPQQLAPPYTYAQGGQQ#TWAPERPLMGVNGLDVTSLRPFDLVIPFTI 1799
|
| Bos taurus |
Query 22 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
|||||||+ || || ||||| |||||||||#||||||||||||||||+|||||||||||||
Sbjct 2023 ALAGDQPTAQPSLRPQQLAPPYTYAQGGQQ#TWAPERPLVGVNGLDVSSLRPFDLVIPFTI 2082
|
| Mus musculus |
Query 22 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
|||||||+|| ||||||||||| | || ||#|| ||||+||||||||||||||||||||||
Sbjct 22 ALAGDQPTVQTPLRSQQLAPQYNYPQGSQQ#TWIPERPMVGVNGLDVTSLRPFDLVIPFTI 81
|
| N/A |
Query 22 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
|||||||+|| ||||||||||| | || ||#|| ||||+||||||||||||||||||||||
Sbjct 1740 ALAGDQPTVQTPLRSQQLAPQYNYPQGSQQ#TWIPERPMVGVNGLDVTSLRPFDLVIPFTI 1799
|
| Rattus norvegicus |
Query 22 ALAGDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
|||||||+|| ||| ||| |||| || ||#|| ||||+||||||||||||||||||||||
Sbjct 1740 ALAGDQPTVQTPLRPQQLPSQYTYPQGSQQ#TWIPERPMVGVNGLDVTSLRPFDLVIPFTI 1799
|
| Gallus gallus |
Query 51 Q#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
|# | ||||+||||||| ||||||||| ||
Sbjct 62 Q#VMATERPLLGVNGLDV-GLRPFDLVIPLTI 91
|
| Tetraodon nigroviridis |
Query 54 APERPLVGVNGLDVTSLRPFDLVIPFTI 81
| +||+ |+||||| ||||||||||||
Sbjct 1718 ATDRPM-GMNGLDVAGLRPFDLVIPFTI 1744
|
| Pan troglodytes |
Query 25 GDQPSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
| | + | + + ++|+ + | #|| | | |+ ++ +|||||||| +
Sbjct 1706 GQYPGLSPGILKDNSSEKHTFMKTKQL#TWVTEEAYVPVSNMNGLGFKPFDLVIPFAV 1762
|
| Danio rerio |
Query 28 PSVQPPLRSQQLAPQYTYAQGGQQ#TWAPERPLVGVNGLDVTSLRPFDLVIPFTI 81
| ++ | || | || # || | |+ |+ ++ ||||+||||||+
Sbjct 1276 PIIEEPCDKLQLQQPYAPYQGYSP#HWATEEPVTAVDIIEPV-LRPFNLVIPFTV 1328
|
