XSB1656 : Myelin basic protein
[ CaMP Format ]
This entry is computationally expanded from SB0045
* Basic Information
| Organism | Equus caballus (horse) |
| Protein Names | MBP |
| Gene Names | MBP |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein |
Entrez Nucleotide |
Entrez Gene |
UniProt |
OMIM |
HGNC |
HPRD |
KEGG |
| P83487 |
N/A |
N/A |
P83487 |
N/A |
N/A |
N/A |
N/A |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 172 aa
Average Mass: 18.725 kDa
Monoisotopic Mass: 18.714 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| --- cleavage 16 --- |
| Myelin_MBP 1. | 16 | 171 | 346.9 | 3.9e-101 |
| --- cleavage 16 (inside Myelin_MBP 16..171) --- |
3. Sequence Information
Fasta Sequence: XSB1656.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] SQRHGSKYLA16-SASTMDHARH
Ala16 
Ser
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Ser7 | Gln8 | Arg9 | His10 | Gly11 | Ser12 | Lys13 | Tyr14 | Leu15 | Ala16 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Ser17 | Ala18 | Ser19 | Thr20 | Met21 | Asp22 | His23 | Ala24 | Arg25 | His26 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
ASQKRPSQRHGSKYLASASTMDHARHGFLPRHRDTGILDSLGRFFG
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
N/A |
98.60 |
13 |
M |
| 2 |
Sus scrofa |
98.60 |
1 |
myelin basic protein |
| 3 |
Pan troglodytes |
96.70 |
20 |
PREDICTED: Golli-mbp isoform 1 |
| 4 |
Homo sapiens |
96.70 |
14 |
myelin basic protein isoform 3 |
| 5 |
Human Golli-mbp gene, complete cds. |
96.70 |
7 |
PREDICTED: similar to |
| 6 |
Pongo pygmaeus |
96.70 |
3 |
hypothetical protein |
| 7 |
Macaca fascicularis |
96.70 |
3 |
unnamed protein product |
| 8 |
Macaca mulatta |
96.70 |
2 |
PREDICTED: similar to Myelin basic protein (MBP) ( |
| 9 |
Canis familiaris |
96.70 |
2 |
PREDICTED: similar to Myelin basic protein (MBP) ( |
| 10 |
synthetic construct |
96.70 |
2 |
myelin basic protein |
| 11 |
Rattus norvegicus |
94.40 |
10 |
myelin basic protein isoform 2 |
| 12 |
Monodelphis domestica |
91.70 |
1 |
PREDICTED: similar to myelin basic protein, |
| 13 |
Bos taurus |
87.00 |
3 |
MBP protein |
| 14 |
Cavia porcellus |
85.10 |
1 |
myelin basic protein; MBP |
| 15 |
Mus musculus |
84.00 |
9 |
myelin basic protein isoform 3 |
| 16 |
Gallus gallus |
70.50 |
1 |
myelin basic protein |
| 17 |
Gekko japonicus |
63.90 |
1 |
GekBS065P |
| 18 |
Xenopus laevis |
62.00 |
3 |
myelin basic protein |
| 19 |
Xenopus tropicalis |
61.60 |
1 |
hypothetical protein LOC549346 |
| 20 |
Heterodontus francisci |
39.70 |
1 |
MBP_HETFR Myelin basic protein (MBP) emb |
Top-ranked sequences
| organism | matching |
|---|
| N/A |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||||||||#||||||||||||||||||||||||||||||
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
|
| Sus scrofa |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||||||||#||||||||||||||||||||||||||||||
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
|
| Pan troglodytes |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||||||||#+|||||||||||||||||||||||+|||||
Sbjct 135 ASQKRPSQRHGSKYLA#TASTMDHARHGFLPRHRDTGILDSIGRFFG 180
|
| Homo sapiens |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||||||||#+|||||||||||||||||||||||+|||||
Sbjct 2 ASQKRPSQRHGSKYLA#TASTMDHARHGFLPRHRDTGILDSIGRFFG 47
|
| Human Golli-mbp gene, complete cds. |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||||||||#+|||||||||||||||||||||||+|||||
Sbjct 135 ASQKRPSQRHGSKYLA#TASTMDHARHGFLPRHRDTGILDSIGRFFG 180
|
| Pongo pygmaeus |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||||||||#+|||||||||||||||||||||||+|||||
Sbjct 2 ASQKRPSQRHGSKYLA#TASTMDHARHGFLPRHRDTGILDSIGRFFG 47
|
| Macaca fascicularis |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||||||||#+|||||||||||||||||||||||+|||||
Sbjct 2 ASQKRPSQRHGSKYLA#TASTMDHARHGFLPRHRDTGILDSIGRFFG 47
|
| Macaca mulatta |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||||||||#+|||||||||||||||||||||||+|||||
Sbjct 127 ASQKRPSQRHGSKYLA#TASTMDHARHGFLPRHRDTGILDSIGRFFG 172
|
| Canis familiaris |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||||||||#||| ||||||||||||||||||||||||||
Sbjct 2 ASQKRPSQRHGSKYLA#SASAMDHARHGFLPRHRDTGILDSLGRFFG 47
|
| synthetic construct |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||||||||#+|||||||||||||||||||||||+|||||
Sbjct 2 ASQKRPSQRHGSKYLA#TASTMDHARHGFLPRHRDTGILDSIGRFFG 47
|
| Rattus norvegicus |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFF 45
||||||||||||||||#+|||||||||||||||||||||||+||||
Sbjct 2 ASQKRPSQRHGSKYLA#TASTMDHARHGFLPRHRDTGILDSIGRFF 46
|
| Monodelphis domestica |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||| ||||||||||#+||||||||||| |||||||||||||||||
Sbjct 142 ASQKRSSQRHGSKYLA#TASTMDHARHGFNPRHRDTGILDSLGRFFG 187
|
| Bos taurus |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
|+||||||| |||||#||||||||||||||||||||||||||||||
Sbjct 22 AAQKRPSQR--SKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 65
|
| Cavia porcellus |
Query 7 SQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||||||||#+|||||||||||||||||||||||+|||||
Sbjct 1 SQRHGSKYLA#TASTMDHARHGFLPRHRDTGILDSIGRFFG 40
|
| Mus musculus |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFF 45
||||||||| |||||#+|||||||||||||||||||||||+||||
Sbjct 2 ASQKRPSQR--SKYLA#TASTMDHARHGFLPRHRDTGILDSIGRFF 44
|
| Gallus gallus |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||| | ||||| +|#|||| |||||| |||||+|+|||||||||
Sbjct 2 ASQKRSSFRHGSK-MA#SASTTDHARHGS-PRHRDSGLLDSLGRFFG 45
|
| Gekko japonicus |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLPRHRDTGILDSLGRFFG 46
||||| | ||||| ||#+|||+|||||| |+|+ +|||||||||
Sbjct 2 ASQKRSSFRHGSK-LA#TASTIDHARHGSPRRYREPSLLDSLGRFFG 46
|
| Xenopus laevis |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGF--LPRHRDTGILDSLGRFFG 46
|||| |+ |||| +|#+||| ||+|||+ ||||+|+|||||||||
Sbjct 2 ASQKH-SRGHGSKQMA#TASTYDHSRHGYGAHGRHRDSGLLDSLGRFFG 48
|
| Xenopus tropicalis |
Query 1 ASQKRPSQRHGSKYLA#SASTMDHARHGFLP--RHRDTGILDSLGRFFG 46
|||| ||||| +|#+||| ||+|||+ ||||+|+|||||||||
Sbjct 132 ASQKL--SRHGSKQMA#TASTSDHSRHGYGAHGRHRDSGLLDSLGRFFG 177
|
| Heterodontus francisci |
Query 15 LA#SASTMDHARH--GFLPRHRDTGILDSLGRFFG 46
+|#|||| ||++ | | ||+|+|| ||+|||
Sbjct 1 MA#SASTSDHSKQAGGAHSRQRDSGLLDQLGKFFG 34
|
* References
[PubMed ID: 12176067] Wood DD, She YM, Freer AD, Harauz G, Moscarello MA, Primary structure of equine myelin basic protein by mass spectrometry. Arch Biochem Biophys. 2002 Sep 1;405(1):137-46.
