CaMPDB :: Substrate

XSB1675 : PREDICTED: Golli-mbp isoform 27 [Pan troglodytes]

This entry is computationally expanded from SB0045

* Basic Information

Organism	Pan troglodytes (chimpanzee)
Protein Names	Golli-mbp isoform 27
Gene Names	MBP; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 13 mRNAs, 14343 ESTs, 9 Proteins
Gene Locus	Not available
GO Function	Not available

Entrez Protein	Entrez Nucleotide	Entrez Gene	UniProt	OMIM	HGNC	HPRD	KEGG
XP_001141944	XM_001141944	455522	N/A	N/A	N/A	N/A	N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 304 aa

Average Mass: 33.087 kDa

Monoisotopic Mass: 33.067 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain name	begin	end	score	e-value
DASH_Hsk3 1.	114	147	-8.4	8.6
Myelin_MBP 1.	150	303	346.3	5.8e-101
--- cleavage 232 (inside Myelin_MBP 150..303) ---

3. Sequence Information

Fasta Sequence: XSB1675.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] FFKNIVTPRT²³²-PPPSQGKGRG

Thr²³² Pro

P10	P9	P8	P7	P6	P5	P4	P3	P2	P1

Phe²²³	Phe²²⁴	Lys²²⁵	Asn²²⁶	Ile²²⁷	Val²²⁸	Thr²²⁹	Pro²³⁰	Arg²³¹	Thr²³²

P1'	P2'	P3'	P4'	P5'	P6'	P7'	P8'	P9'	P10'
Pro²³³	Pro²³⁴	Pro²³⁵	Ser²³⁶	Gln²³⁷	Gly²³⁸	Lys²³⁹	Gly²⁴⁰	Arg²⁴¹	Gly²⁴²

Sequence conservation (by blast) Sequence conservation (by blast)

Reference peptide (cleaved bond±30 residues)
YGSLPQKSHGRTQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQRPGFGYG

Summary

#	organism	max score	hits	top seq
1	N/A	132.00	21	-
2	Pan troglodytes	132.00	18	PREDICTED: Golli-mbp isoform 27
3	Homo sapiens	132.00	12	Golli-mbp isoform 1
4	Human Golli-mbp gene, complete cds.	132.00	6	PREDICTED: similar to
5	Pongo pygmaeus	132.00	3	hypothetical protein
6	synthetic construct	132.00	2	myelin basic protein
7	Macaca mulatta	131.00	2	PREDICTED: similar to myelin basic protein isoform
8	Mus musculus	127.00	8	myelin basic protein isoform 1
9	Canis familiaris	124.00	1	PREDICTED: similar to Myelin basic protein (MBP) (
10	Bos taurus	123.00	2	PREDICTED: myelin basic protein
11	Sus scrofa	123.00	1	myelin basic protein
12	Rattus norvegicus	121.00	9	myelin basic protein isoform 1
13	Cavia porcellus	120.00	1	myelin basic protein; MBP
14	Monodelphis domestica	114.00	1	PREDICTED: similar to myelin basic protein,
15	Gallus gallus	101.00	1	myelin basic protein
16	Macaca fascicularis	100.00	2	unnamed protein product
17	Xenopus laevis	87.00	2	hypothetical protein LOC734401
18	Gekko japonicus	84.30	1	GekBS065P
19	Heterodontus francisci	52.40	1	MBP_HETFR Myelin basic protein (MBP) emb
20	cattle, brain, Peptide Partial, 17 aa, segment 3 of 3	38.10	1	clathrin assembly protein=myelin basic protein (MB
21	Danio rerio	32.70	2	Mbp protein

Top-ranked sequences

organism	matching
N/A	Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262
Pan troglodytes	Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262
Homo sapiens	Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262
Human Golli-mbp gene, complete cds.	Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262
Pongo pygmaeus	Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262
synthetic construct	Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262
Macaca mulatta	Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\|\| Sbjct 200 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQKPGFGYG 259
Mus musculus	Query 203 YGSLPQKS-HGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGY 261 \|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\| Sbjct 92 YGSLPQKSQHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQKPGFGY 151 Query 262 G 262 \| Query 262 G 262
Canis familiaris	Query 203 YGSLPQKS-HGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGY 261 \|\|\|\|\|\|\|\| \|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\| Sbjct 70 YGSLPQKSQHGRPQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQKPGFGY 129 Query 262 G 262 \| Query 262 G 262
Bos taurus	Query 203 YGSLPQKS-HGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGY 261 \|\|\|\|\|\|\|+ \|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\| Sbjct 432 YGSLPQKAQHGRPQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQKPGFGY 491 Query 262 G 262 \| Query 262 G 262
Sus scrofa	Query 203 YGSLPQKS-HGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGY 261 \|\|\|\|\|\|\|+ \|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\| Sbjct 70 YGSLPQKAQHGRPQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQKPGFGY 129 Query 262 G 262 \| Query 262 G 262
Rattus norvegicus	Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\|\| Sbjct 94 YGSLPQKSQ-RTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQKPGFGYG 152
Cavia porcellus	Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\| \|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\|\| Sbjct 63 YGSLPQKSQ-RSQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQKPGFGYG 121
Monodelphis domestica	Query 203 YGSLPQKS-HGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGY 261 \|\|\|\|\|\|\|\| \|\|\|\| \|+\|\|\|\|\|\|\|\|\|\|\|+\|\|\|#\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\|\| \|\| Sbjct 210 YGSLPQKSQHGRTYDDNPVVHFFKNIVSPRT#PPAGQGKGRGLSLSRFSWGAEGQKPGCGY 269 Query 262 G 262 \| Query 262 G 262
Gallus gallus	Query 204 GSLPQKS-HGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|+\|\|+\| \|\|\| \|+\|\|\|\|\|\|\|\|\|\|\|+\|\|\|#\|\|\| \| \|\|\|\|\|\|\|+\|\|\|\|\| \|\| +\|\|+\| \| Sbjct 68 GSIPQRSQHGRPGDDNPVVHFFKNIVSPRT#PPPMQAKGRGLSLTRFSWGGEGHKPGYGSG 127
Macaca fascicularis	Query 203 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| \|\|\|\|\|+\|\|\|\|\|\| Sbjct 70 YGSLPQKSHGRTQDENPVVHFFKNIVTPRT#PPPSQGK-----------GAEGQKPGFGYG 118
Xenopus laevis	Query 205 SLPQKSH----GRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGF- 259 \| \|\|+\|\| \|\| \|\|\|\|\|\|\|\|\|+\|\|\|+\|\|\|#\|\|\|\|\| \| \|\|\|\|\|+\|\|\|\|\|\|+\| \|\| + Sbjct 72 SSPQRSHYYAHGRHVDENPVVHFFRNIVSPRT#PPPSQPK-RGLSLARFSWGADGHRPCYG 130 Query 260 GYG 262 \|\|\| Query 260 GYG 262
Gekko japonicus	Query 211 HGRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLSLSRFSWGAEGQRPGFGYG 262 +\|\| \|+\|\|\|\|\|\|\|\|\|\|\|+\|\|\|#\|\|\| \| \|\|\|\|\|\| \|\|\|\|\|\| \| + \|+\| \| Sbjct 80 YGRYVDDNPVVHFFKNIVSPRT#PPPMQAKGRGLSFSRFSWGGETPKHGYGSG 131
Heterodontus francisci	Query 212 GRTQDENPVVHFFKNIVTPRT#PPPSQGKGRGLS--LSRFSWGAEGQRPGFG 260 \|\| \|++ \|\|\|\|\|\|\|+++\|+ # \| \| \| \| +++\| \|\| +\|\|\|\| +\| Sbjct 67 GRQTDDSAVVHFFKNMMSPKK#APVQQKARSGASRAITKFIWGTDGQRPHYG 117
cattle, brain, Peptide Partial, 17 aa, segment 3 of 3	Query 248 FSWGAEGQRPGFGYG 262 \|\|\|\|\|\|\|\|+\|\|\|\|\|\| Sbjct 1 FSWGAEGQKPGFGYG 15
Danio rerio	Query 205 SLPQKSHG----RTQDENPVVHFFKNIV-TPRT#PPPSQGKGRGLS 244 \| \|\|+ \| \| \| \|\|\|\|\|\|\|++ \| +\|\| # \| \|+\|+ \| \| Sbjct 49 SSPQRPHHSSTRRRGDVNPVVHFFRSFVSSPR-#-PKSRGESRSRS 91

* References

None.