XSB1690 : Tyrosine 3-monooxygenase
[ CaMP Format ]
This entry is computationally expanded from SB0059
* Basic Information
| Organism | Bos taurus (cattle) |
| Protein Names | Tyrosine 3-hydroxylase; TH; 1.14.16.2 |
| Gene Names | TH |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| P17289 | N/A | N/A | P17289 | N/A | N/A | N/A | bta:280707 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 491 aa
Average Mass: 55.123 kDa
Monoisotopic Mass: 55.089 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| --- cleavage 22 --- | ||||
| DUF1213 1. | 33 | 62 | 6.4 | 7.5 |
| ACT 1. | 77 | 147 | 6.8 | 1.6 |
| Biopterin_H 1. | 158 | 489 | 993.7 | 7.8e-296 |
3. Sequence Information
Fasta Sequence: XSB1690.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] GFRRAVSELD22-AKQAEAIMSP
Asp22 
Ala
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Gly13 | Phe14 | Arg15 | Arg16 | Ala17 | Val18 | Ser19 | Glu20 | Leu21 | Asp22 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ala23 | Lys24 | Gln25 | Ala26 | Glu27 | Ala28 | Ile29 | Met30 | Ser31 | Pro32 |
Sequence conservation (by blast)
* References
[PubMed ID: 2898537] D'Mello SR, Weisberg EP, Stachowiak MK, Turzai LM, Gioio AE, Kaplan BB, Isolation and nucleotide sequence of a cDNA clone encoding bovine adrenal tyrosine hydroxylase: comparative analysis of tyrosine hydroxylase gene products. J Neurosci Res. 1988 Apr;19(4):440-9.