XSB1703 : PREDICTED: similar to poly(ADP-ribose) synthetase [Monodelphis domestica]
[ CaMP Format ]
This entry is computationally expanded from SB0065
* Basic Information
| Organism | Monodelphis domestica (gray short-tailed opossum) |
| Protein Names | similar to poly(ADP-ribose) synthetase |
| Gene Names | LOC100019495; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 2 Proteins |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| XP_001368346 | XM_001368309 | 100019495 | N/A | N/A | N/A | N/A | N/A |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 1011 aa
Average Mass: 112.944 kDa
Monoisotopic Mass: 112.872 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| zf-PARP 1. | 12 | 90 | 139.9 | 8.2e-39 |
| zf-PARP 2. | 116 | 200 | 139.6 | 1e-38 |
| PADR1 1. | 278 | 331 | 116.1 | 1.1e-31 |
| BRCT 1. | 383 | 461 | 48.3 | 3e-11 |
| WGR 1. | 545 | 630 | 132.6 | 1.3e-36 |
| --- cleavage 653 --- | ||||
| PARP_reg 1. | 659 | 792 | 288.6 | 1.4e-83 |
| PARP 1. | 794 | 1004 | 430.3 | 2.9e-126 |
3. Sequence Information
Fasta Sequence: XSB1703.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] QDEEAVKKLT653-VSAGTKSKLP
Thr653 
Val
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Gln644 | Asp645 | Glu646 | Glu647 | Ala648 | Val649 | Lys650 | Lys651 | Leu652 | Thr653 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Val654 | Ser655 | Ala656 | Gly657 | Thr658 | Lys659 | Ser660 | Lys661 | Leu662 | Pro663 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| HSTNFTKYPKKFYPLEIDYGQDEEAVKKLTVSAGTKSKLPIPVQNLIKMIFDVESMKKAM |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Monodelphis domestica | 123.00 | 1 | PREDICTED: similar to poly(ADP-ribose) synthetase |
| 2 | ADP-ribose | 113.00 | 19 | PARP1_HUMAN Poly |
| 3 | N/A | 113.00 | 9 | - |
| 4 | Homo sapiens | 113.00 | 8 | poly (ADP-ribose) polymerase family, member 1 |
| 5 | Bos taurus | 113.00 | 2 | ADP-ribosyltransferase (NAD+) poly (ADP-ribose) po |
| 6 | cattle, Peptide Partial, 607 aa | 113.00 | 1 | NAD+:protein(ADP-ribosyl)-transferase, ADPRT |
| 7 | synthetic construct | 113.00 | 1 | poly (ADP-ribose) polymerase family, member 1 |
| 8 | Macaca mulatta | 112.00 | 5 | PREDICTED: poly (ADP-ribose) polymerase family, me |
| 9 | Macaca fascicularis | 112.00 | 1 | unnamed protein product |
| 10 | chickens, Peptide Partial, 607 aa | 111.00 | 1 | NAD+:protein(ADP-ribosyl)-transferase, ADPRT |
| 11 | Gallus gallus | 111.00 | 1 | poly (ADP-ribose) polymerase family, member 1 |
| 12 | Mus musculus | 108.00 | 11 | poly (ADP-ribose) polymerase family, member 1 |
| 13 | mice, Peptide Partial, 606 aa | 107.00 | 1 | NAD+:protein(ADP-ribosyl)-transferase, ADPRT |
| 14 | Rattus norvegicus | 106.00 | 2 | ADP-ribosyltransferase 1 |
| 15 | Tetraodon nigroviridis | 105.00 | 1 | unnamed protein product |
| 16 | Xenopus laevis | 104.00 | 3 | NAD(+) ADP-ribosyltransferase |
| 17 | Xenopus, Peptide Partial, 607 aa | 104.00 | 1 | NAD+:protein(ADP-ribosyl)-transferase, ADPRT |
| 18 | Danio rerio | 102.00 | 2 | Zgc:110092 |
| 19 | Anopheles gambiae str. PEST | 57.80 | 1 | ENSANGP00000014723 |
| 20 | adp-ribose | 53.50 | 1 | poly |
| 21 | Drosophila melanogaster | 52.40 | 3 | CG40411-PC.3 |
| 22 | Drosophila, Peptide Partial, 593 aa | 52.40 | 1 | NAD+:protein(ADP-ribosyl)-transferase, ADPRT |
| 23 | Arabidopsis thaliana | 50.80 | 2 | putative poly (ADP-ribose) polymerase |
| 24 | Vitis vinifera | 49.70 | 1 | hypothetical protein |
| 25 | Zea mays | 47.80 | 1 | poly(ADP-ribose) polymerase |
| 26 | Oryza sativa (japonica cultivar-group) | 47.00 | 5 | Os07g0413700 |
| 27 | Oryza sativa (indica cultivar-group) | 47.00 | 2 | hypothetical protein OsI_024833 |
| 28 | Schistosoma japonicum | 42.40 | 1 | SJCHGC03992 protein |
| 29 | Caenorhabditis briggsae | 39.70 | 1 | Hypothetical protein CBG04221 |
| 30 | Dictyostelium discoideum AX4 | 39.30 | 3 | poly(ADP-ribosyl)transferase |
| 31 | Dictyostelium discoideum | 39.30 | 2 | NAD(+) ADP-ribosyltransferase-1A |
| 32 | Caenorhabditis elegans | 39.30 | 2 | Poly(ADP-ribose) Metabolism Enzyme family member ( |
| 33 | Pan troglodytes | 38.90 | 3 | PREDICTED: poly (ADP-ribose) polymerase family, me |
| 34 | Trypanosoma brucei brucei | 37.70 | 1 | poly(ADP-ribose) polymerase |
| 35 | Trypanosoma brucei TREU927 | 37.70 | 1 | poly(ADP-ribose) polymerase, putative |
| 36 | Dictyostelium discoideum, Peptide Partial, 612 aa | 34.70 | 1 | NAD+:protein(ADP-ribosyl)-transferase, ADPRT {EC 2 |
| 37 | Clostridium acetobutylicum ATCC 824 | 33.10 | 1 | Multidrug-efflux transporter transcription regulat |
Top-ranked sequences
| organism | matching |
|---|---|
| Monodelphis domestica | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 |
| ADP-ribose | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||||||#|+ ||||||| |||+||||||||||||||| Sbjct 627 HSKNFTKYPKKFYPLEIDYGQDEEAVKKLT#VNPGTKSKLPKPVQDLIKMIFDVESMKKAM 686 |
| N/A | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||||||#|+ ||||||| |||+||||||||||||||| Sbjct 627 HSKNFTKYPKKFYPLEIDYGQDEEAVKKLT#VNPGTKSKLPKPVQDLIKMIFDVESMKKAM 686 |
| Homo sapiens | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||||||#|+ ||||||| |||+||||||||||||||| Sbjct 627 HSKNFTKYPKKFYPLEIDYGQDEEAVKKLT#VNPGTKSKLPKPVQDLIKMIFDVESMKKAM 686 |
| Bos taurus | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || ||||+||||||||||||||||||||||#|+ ||||||| ||||||||||||||||||| Sbjct 629 HSKNFTKHPKKFYPLEIDYGQDEEAVKKLT#VNPGTKSKLPKPVQNLIKMIFDVESMKKAM 688 |
| cattle, Peptide Partial, 607 aa | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || ||||+||||||||||||||||||||||#|+ ||||||| ||||||||||||||||||| Sbjct 220 HSKNFTKHPKKFYPLEIDYGQDEEAVKKLT#VNPGTKSKLPKPVQNLIKMIFDVESMKKAM 279 |
| synthetic construct | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||||||#|+ ||||||| |||+||||||||||||||| Sbjct 627 HSKNFTKYPKKFYPLEIDYGQDEEAVKKLT#VNPGTKSKLPKPVQDLIKMIFDVESMKKAM 686 |
| Macaca mulatta | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||||||#|+ ||||||| |||+|||+||||||||||| Sbjct 627 HSKNFTKYPKKFYPLEIDYGQDEEAVKKLT#VNPGTKSKLPKPVQDLIKLIFDVESMKKAM 686 |
| Macaca fascicularis | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||||||#|+ ||||||| |||+|||+||||||||||| Sbjct 24 HSKNFTKYPKKFYPLEIDYGQDEEAVKKLT#VNPGTKSKLPKPVQDLIKLIFDVESMKKAM 83 |
| chickens, Peptide Partial, 607 aa | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||+|||#||||||||| |+|+||||||||||||||| Sbjct 220 HSKNFTKYPKKFYPLEIDYGQDEEAVRKLT#VSAGTKSKLAKPIQDLIKMIFDVESMKKAM 279 |
| Gallus gallus | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||+|||#||||||||| |+|+||||||||||||||| Sbjct 624 HSKNFTKYPKKFYPLEIDYGQDEEAVRKLT#VSAGTKSKLAKPIQDLIKMIFDVESMKKAM 683 |
| Mus musculus | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||||||#| ||||||| ||| |+ |||||||||||+ Sbjct 627 HSKNFTKYPKKFYPLEIDYGQDEEAVKKLT#VKPGTKSKLPKPVQELVGMIFDVESMKKAL 686 |
| mice, Peptide Partial, 606 aa | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||||||#| ||||||| ||| |+ |||||+|||||+ Sbjct 219 HSKNFTKYPKKFYPLEIDYGQDEEAVKKLT#VKPGTKSKLPKPVQELVGMIFDVDSMKKAL 278 |
| Rattus norvegicus | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || |||||||||||||||||||||||||| #| ||||||| ||| |+ |||||||||||+ Sbjct 627 HSKNFTKYPKKFYPLEIDYGQDEEAVKKLA#VKPGTKSKLPKPVQELVGMIFDVESMKKAL 686 |
| Tetraodon nigroviridis | Query 625 STNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 |+|||||| ||||||||||||||||||||# +||||||| ||| ||||||||||||||| Sbjct 370 SSNFTKYPNKFYPLEIDYGQDEEAVKKLT#ATAGTKSKLAKPVQELIKMIFDVESMKKAM 428 |
| Xenopus laevis | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || ||||||||||||||||||+|+ ||||+#| ||||||| ||| |||+||||||||||| Sbjct 623 HSPNFTKYPKKFYPLEIDYGQEEDVVKKLS#VGAGTKSKLAKPVQELIKLIFDVESMKKAM 682 |
| Xenopus, Peptide Partial, 607 aa | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || ||||||||||||||||||+|+ ||||+#| ||||||| ||| |||+||||||||||| Sbjct 219 HSPNFTKYPKKFYPLEIDYGQEEDVVKKLS#VGAGTKSKLAKPVQELIKLIFDVESMKKAM 278 |
| Danio rerio | Query 625 STNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 |+|||||| ||||||||||||||||||||# ||| ||+| |||+||+|||||||||||| Sbjct 625 SSNFTKYPNKFYPLEIDYGQDEEAVKKLT#QSAGAKSQLEKPVQDLIRMIFDVESMKKAM 683 |
| Anopheles gambiae str. PEST | Query 624 HSTNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 | + ++| | |||+|||| | |+| # ++| |||| ||+|++|+|||++| + | Sbjct 610 HDSVYSKMPGAFYPIEIDYS--ETKTKRLA#ENSGIKSKLAPAVQDLVRMLFDVDAMNRVM 667 |
| adp-ribose | Query 628 FTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 | |+| +||++||| +| | | # + |||| ||+|++|+|||++||| | Sbjct 620 FHKHPGAYYPVDIDYNDEE--TKTLA#ENNDIKSKLEPAVQDLVRMLFDVDTMKKVM 673 |
| Drosophila melanogaster | Query 627 NFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || | + ||+|| | |++ || # | ||| | ||||||+|||++|| | + Sbjct 614 NFVKRTGRMYPIEIQYDDDQKLVKH--#ESHFFTSKLEISVQNLIKLIFDIDSMNKTL 668 |
| Drosophila, Peptide Partial, 593 aa | Query 627 NFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || | + ||+|| | |++ || # | ||| | ||||||+|||++|| | + Sbjct 213 NFVKRTGRMYPIEIQYDDDQKLVKH--#ESHFFTSKLEISVQNLIKLIFDIDSMNKTL 267 |
| Arabidopsis thaliana | Query 626 TNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 ||| | | || ||+|||| +++ || # | | | + |+||+||||+ + || Sbjct 628 TNFQKQPGKFLPLDIDYGVNKQVAKKEP#FQ--TSSNLAPSLIELMKMLFDVETYRSAM 683 |
| Vitis vinifera | Query 627 NFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 || | | +|+||+|||| +++ || #+| |+| | |+||+|+||+ + || Sbjct 627 NFQKQPGRFFPLDIDYGVNKQVSKKNN#LS-NVNSQLAPQVVELMKMLFNVETYRSAM 682 |
| Zea mays | Query 626 TNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 ||| | | +||||++||| ++| |+ #+| || | + |+||+|+||+ + || Sbjct 587 TNFRKQPGRFYPLDVDYGV-KKAPKRKD#ISE-MKSSLAPQLLELMKMLFNVETYRAAM 642 |
| Oryza sativa (japonica cultivar-group) | Query 626 TNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 ||| | | |||||+|||| + |+ #+ || || + |+ |+|++|+ + || Sbjct 595 TNFQKQPGKFYPLDIDYGV-RQGPKRKD#IDK-MKSSLPPQLLELMNMLFNIETYRAAM 650 |
| Oryza sativa (indica cultivar-group) | Query 626 TNFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 ||| | | |||||+|||| + |+ #+ || || + |+ |+|++|+ + || Sbjct 578 TNFQKQPGKFYPLDIDYGV-RQGPKRKD#IDK-MKSSLPPQLLELMNMLFNIETYRAAM 633 |
| Schistosoma japonicum | Query 627 NFTKYPKKFYPLEIDYG-QDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 +| |+ |+ +||||| ||| + # + ||+||+ || |+++| |+++|++ | Sbjct 133 HFIKHKGKYDLVEIDYGVQDENVTIETK#KTEEIKSRLPVAVQVLMQLICDMDNMEQVM 190 |
| Caenorhabditis briggsae | Query 627 NFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 +| | | | +| || + ++ +|+ #+ |+++ || |+ ++ |||+|+|| |+ Sbjct 546 HFRKMPGAFSFVETDYSEFDQ-LKEQD#IIPGSRTLLPRAVKEIVMSIFDIENMKSAL 601 |
| Dictyostelium discoideum AX4 | Query 628 FTKYPKKFYPLEIDYGQDEEAVKKL-----------T#VSAGT-------KSKLPIPVQNL 669 | | |+|+| + +| | ||| + | |# + | | || | +| Sbjct 541 FKKLPRKYYMISLDDGNDEEEEENLVETVLKRKKSET#TTTSTSQEIEPKKEGLPQRVLDL 600 Query 670 IKMIFDVESMKKAM 683 +|++|| | ||| + Sbjct 601 VKLMFDPEMMKKQL 614 |
| Dictyostelium discoideum | Query 628 FTKYPKKFYPLEIDYGQDEEAVKKL-----------T#VSAGT-------KSKLPIPVQNL 669 | | |+|+| + +| | ||| + | |# + | | || | +| Sbjct 541 FKKLPRKYYMISLDDGNDEEEEENLVETVLKRKKSET#TTTSTSQEIEPKKEGLPQRVLDL 600 Query 670 IKMIFDVESMKKAM 683 +|++|| | ||| + Sbjct 601 VKLMFDPEMMKKQL 614 |
| Caenorhabditis elegans | Query 627 NFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESMKKAM 683 +| | | | +| || + + + #++ |+|+ || |+ ++ |||||+|| |+ Sbjct 555 HFRKMPGMFSYVETDYSEFAQ-ITDTE#ITPGSKTLLPKSVKEVVMSIFDVENMKSAL 610 |
| Pan troglodytes | Query 628 FTKYPKKFYPLEIDYG---QDEEAVKK---LT#VSAGTKSKLPIPVQNLIKMIFDVESMKK 681 | | | |+ |++|| |||| || | # +|+| + || |||+| +|++|++ Sbjct 194 FEKVPGKYDMLQMDYATNTQDEEETKKEESLK#SPLKPESQLDLRVQELIKLICNVQAMEE 253 Query 682 AM 683 | Sbjct 254 MM 255 |
| Trypanosoma brucei brucei | Query 628 FTKYPKKFYPLEIDYGQDEE--------AVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESM 679 | | | |+ +|+|||+|++ || # +|||| ||+|+++| ||| Sbjct 190 FKKVPGKYEYMEVDYGEDDDDDAGGEKPGKKKKA#EKPVRESKLPKEVQDLMRLIGCRESM 249 Query 680 KKAM 683 + + Sbjct 250 SQVL 253 |
| Trypanosoma brucei TREU927 | Query 628 FTKYPKKFYPLEIDYGQDEE--------AVKKLT#VSAGTKSKLPIPVQNLIKMIFDVESM 679 | | | |+ +|+|||+|++ || # +|||| ||+|+++| ||| Sbjct 190 FKKVPGKYEYMEVDYGEDDDDDAGGEKPGKKKKA#EKPVRESKLPKEVQDLMRLIGCRESM 249 Query 680 KKAM 683 + + Sbjct 250 SQVL 253 |
| Dictyostelium discoideum, Peptide Partial, 612 aa | Query 627 NFTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKS-----------KLPIPVQNLIKMIFD 675 || | |+ +|+|| | + +# +| | + | || |+|+||| Sbjct 228 NFKKVAGKYDMIELDYSTDSKPKNGAS#TTATTTTTKKVVEHKKECSLDERVQELVKLIFD 287 Query 676 VESMKKAM 683 |+ |++ | Sbjct 288 VKMMERTM 295 |
| Clostridium acetobutylicum ATCC 824 | Query 628 FTKYPKKFYPLEIDYGQDEEAVKKLT#VSAGTKSK-LPIPVQNLIKMIFDVESMK 680 || || | +| ||+||++ + #+| ||| | | || | | |++| Sbjct 127 FTYEDKKAYMIEPCYGKDEKSYMQSF#ISICNKSKELQIDFQNPICSIITKEALK 180 |
* References
None.