XSB1855 : alpha-fodrin (382 AA) [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0061
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | Spectrin alpha chain, brain; Spectrin, non-erythroid alpha chain; Alpha-II spectrin; Fodrin alpha chain; alpha-fodrin (382 AA) |
| Gene Names | Spna2, Spta2; Spna2; Spta2 |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 382 aa
Average Mass: 0.000 kDa
Monoisotopic Mass: 0.000 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| SH3_1 1. | 2 | 30 | -4.4 | 0.11 |
| Spectrin 1. | 77 | 217 | 63.3 | 8.8e-16 |
| --- cleavage 162 (inside Spectrin 77..217) --- | ||||
| Spectrin 2. | 219 | 323 | 145.5 | 1.6e-40 |
3. Sequence Information
Fasta Sequence: XSB1855.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] VQAVQQQEVY162-GAMPRDEADS
Tyr162 
Gly
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Val153 | Gln154 | Ala155 | Val156 | Gln157 | Gln158 | Gln159 | Glu160 | Val161 | Tyr162 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Gly163 | Ala164 | Met165 | Pro166 | Arg167 | Asp168 | Glu169 | Ala170 | Asp171 | Ser172 |
Sequence conservation (by blast)
* References
[PubMed ID: 2111175] Sri Widada J, Asselin J, Colote S, Ferraz C, Trave G, Afshar M, Haiech J, Liautard JP, Identification of the calmodulin binding domain of alpha-fodrin and implications for folding. Biochimie. 1990 Jan;72(1):19-24.