XSB1861 : BCL2-associated X protein [Bos taurus]
[ CaMP Format ]
This entry is computationally expanded from SB0026
* Basic Information
| Organism | Bos taurus (cattle) |
| Protein Names | Apoptosis regulator BAX; BCL2-associated X protein |
| Gene Names | BAX; BCL2-associated X protein |
| Gene Locus | 18; chromosome 18 |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| NP_776319 | NM_173894 | 280730 | O02703 | N/A | N/A | N/A | bta:280730 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 192 aa
Average Mass: 21.259 kDa
Monoisotopic Mass: 21.246 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| --- cleavage 28 --- | ||||
| Bcl-2 1. | 63 | 158 | 157.0 | 5.5e-44 |
3. Sequence Information
Fasta Sequence: XSB1861.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] IMKTGALLLQ28-GFIQDRAGRM
Gln28 
Gly
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Ile19 | Met20 | Lys21 | Thr22 | Gly23 | Ala24 | Leu25 | Leu26 | Leu27 | Gln28 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Gly29 | Phe30 | Ile31 | Gln32 | Asp33 | Arg34 | Ala35 | Gly36 | Arg37 | Met38 |
Sequence conservation (by blast)
* References
[PubMed ID: 18962879] Vireque AA, Camargo LS, Serapiao RV, Rosa E Silva AA, Watanabe YF, Ferreira EM, Navarro PA, Martins WP, Ferriani RA, Preimplantation development and expression of Hsp-70 and Bax genes in bovine blastocysts derived from oocytes matured in alpha-MEM supplemented with growth factors and synthetic macromolecules. Theriogenology. 2009 Mar 1;71(4):620-7. Epub 2008 Oct 28.