XSB1884 : S-arrestin
[ CaMP Format ]
This entry is computationally expanded from SB0025
* Basic Information
| Organism | Bos taurus (cattle) |
| Protein Names | Retinal S-antigen; S-AG; 48 kDa protein; Rod photoreceptor arrestin; S-arrestin short form |
| Gene Names | SAG |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| P08168 | N/A | N/A | P08168 | N/A | N/A | N/A | bta:280922 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 404 aa
Average Mass: 45.275 kDa
Monoisotopic Mass: 45.247 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Arrestin_N 1. | 22 | 180 | 203.9 | 4.4e-58 |
| Arrestin_C 1. | 199 | 360 | 142.9 | 9.7e-40 |
3. Sequence Information
Fasta Sequence: XSB1884.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
* Cleavage Information
2 [sites]
Cleavage sites (±10aa)
[Site 1] VFEEFARQNL385-KDAGEYKEEK
Leu385 
Lys
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Val376 | Phe377 | Glu378 | Glu379 | Phe380 | Ala381 | Arg382 | Gln383 | Asn384 | Leu385 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Lys386 | Asp387 | Ala388 | Gly389 | Glu390 | Tyr391 | Lys392 | Glu393 | Glu394 | Lys395 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| MHPQPEDPDTAKESFQDENFVFEEFARQNLKDAGEYKEEKTDQEAAMDE |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 105.00 | 3 | A |
| 2 | Bos taurus | 105.00 | 3 | put. S-antigen C-terminus |
| 3 | Contains: S-arrestin short form | 105.00 | 1 | ARRS_BOVIN S-arrestin (Retinal S-antigen) (48 kDa |
| 4 | Sus scrofa | 85.50 | 1 | S-antigen |
| 5 | Mus musculus | 72.80 | 6 | Retinal S-antigen |
| 6 | Canis familiaris | 72.80 | 4 | PREDICTED: arrestin, S-antigen |
| 7 | Rattus norvegicus | 72.80 | 3 | S-antigen |
| 8 | Canis lupus familiaris | 70.50 | 1 | S-arrestin |
| 9 | Homo sapiens | 66.20 | 8 | arrestin |
| 10 | Cavia porcellus | 65.90 | 1 | S-antigen |
| 11 | Macaca mulatta | 65.50 | 2 | PREDICTED: S-arrestin isoform 1 |
| 12 | Xenopus tropicalis | 48.10 | 1 | S-antigen; retina and pineal gland (arrestin) |
| 13 | Rana pipiens | 45.80 | 1 | ARRS_RANPI S-arrestin (Retinal S-antigen) (Rod pho |
| 14 | Rana catesbeiana | 45.40 | 2 | ARRS_RANCA S-arrestin (Retinal S-antigen) (Rod pho |
| 15 | Xenopus laevis | 43.90 | 3 | MGC84416 protein |
| 16 | Gallus gallus | 43.90 | 2 | PREDICTED: hypothetical protein |
| 17 | Ambystoma tigrinum | 36.60 | 2 | AF203327_1 rod arrestin |
| 18 | Gekko gecko | 36.20 | 1 | arrestin |
| 19 | Danio rerio | 35.00 | 1 | arrestin |
| 20 | human, Peptide, 410 aa | 33.90 | 1 | beta-arrestin 1 gb |
| 21 | Pan troglodytes | 33.90 | 1 | PREDICTED: arrestin beta 1 |
| 22 | human, Peptide, 418 aa | 33.90 | 1 | beta-arrestin 1 gb |
| 23 | Oryctolagus cuniculus | 33.90 | 1 | ARRB1_RABIT Beta-arrestin-1 (Arrestin beta 1) gb |
| 24 | Ehrlichia ruminantium str. Welgevonden | 33.10 | 1 | putative cell division protein FtsK |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 ||||||||||||||||||||||||||||||#||||||||||||||||||| Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 |
| Bos taurus | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 ||||||||||||||||||||||||||||||#||||||||||||||||||| Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 |
| Contains: S-arrestin short form | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 ||||||||||||||||||||||||||||||#||||||||||||||||||| Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 |
| Sus scrofa | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 ||||||||+ | +|||||||||||||||||#||||| |||||||||| | Sbjct 358 MHPQPEDPE-AMDSFQDENFVFEEFARQNL#KDAGELKEEKTDQEAAAHE 405 |
| Mus musculus | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 |||||||| |||| |||| ||||||||||#|| || | | |++| || Sbjct 357 MHPQPEDP--AKESVQDENLVFEEFARQNL#KDTGENPEGKKDEDAGQDE 403 |
| Canis familiaris | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 |||||||| |||||||||| ||||||||||#|| | | | |+| |||| Sbjct 360 MHPQPEDPATAKESFQDENLVFEEFARQNL#KDFAE--EGKKDRE-AMDE 405 |
| Rattus norvegicus | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 |||||||| |||| |||| ||||||||||#|| || | | |++| || Sbjct 357 MHPQPEDP--AKESVQDENLVFEEFARQNL#KDTGENTEGKKDEDAGQDE 403 |
| Canis lupus familiaris | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 |||||||| |||||||| | ||||||||||#|| | | | |+| |||| Sbjct 360 MHPQPEDPATAKESFQDANLVFEEFARQNL#KDFAE--EGKKDRE-AMDE 405 |
| Homo sapiens | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAA 401 |||||||| ||||+|| | ||||||| ||#||||| +| | |+ | Sbjct 360 MHPQPEDP--AKESYQDANLVFEEFARHNL#KDAGEAEEGKRDKNDA 403 |
| Cavia porcellus | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKE-EKTDQEAAMDE 404 ||||||| |||+ |||| ||||||||||#|| || | +| ++||| || Sbjct 357 MHPQPED--TAKDGLQDENLVFEEFARQNL#KDVGEGGEGKKEEEEAAPDE 404 |
| Macaca mulatta | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQ 398 |||||||| ||||+|| | ||||||| ||#||||| +| | |+ Sbjct 360 MHPQPEDP--AKESYQDANLVFEEFARHNL#KDAGEAEEGKRDK 400 |
| Xenopus tropicalis | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KD--AGEYKEEKTDQE 399 ||| || +|||| ||++ ||||||| |#|| | |||+ | | Sbjct 352 MHPNPE---SAKESEQDDDMVFEEFARDQL#KDELQAEEKEEEEDDE 394 |
| Rana pipiens | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQE 399 |||+|+ |||| |+|+||||+||| +|#|| + +|++ ++| Sbjct 352 MHPKPDSG--AKESEQEEDFVFEDFARDHL#KDELQPEEKEEEEE 393 |
| Rana catesbeiana | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQE 399 |||+|+ |||| |+|+||||+||| |#|| + +|++ ++| Sbjct 352 MHPKPDSG--AKESEQEEDFVFEDFARDQL#KDELQPEEKEEEEE 393 |
| Xenopus laevis | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KD--AGEYKEEKTDQE 399 ||| || |||| ||++ ||||||| |#| | |||+ | | Sbjct 352 MHPNPESG--AKESEQDDDMVFEEFARDPL#KGELQAEEKEEEEDDE 395 |
| Gallus gallus | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEK 395 |||+||+ ++| + | |||||||| |#|| |+ +| | Sbjct 362 MHPKPEEKNSAGKD-GDAEMVFEEFARQQL#KDTGDEEENK 400 |
| Ambystoma tigrinum | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQEAAMDE 404 |||+|| |+++ |||||||+ |#|| + +++ |++ |+ Sbjct 355 MHPKPESAGD-----QEDDLVFEEFAREQL#KDELQPEDKDKDEDEDDDK 398 |
| Gekko gecko | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQE 399 |||+| | +||+ +|+ | |||||| +#| + ||| +++ Sbjct 293 MHPKPTD-NTARS---EEDIVIEEFARQKI#KGEPDDDEEKEEED 332 |
| Danio rerio | Query 356 MHPQPEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEE 394 |||+| | ||| +| ||||| | |#| | ++| Sbjct 348 MHPKP---DAVKESEAEEEMVFEEFKRTYL#KGMPEDEDE 383 |
| human, Peptide, 410 aa | Query 360 PEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTD 397 | | + + |++ |||+|||| |#| + |||+ | Sbjct 363 PVDTNLIELDTNDDDIVFEDFARQRL#KGMEDDKEEEED 400 |
| Pan troglodytes | Query 360 PEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTD 397 | | + + |++ |||+|||| |#| + |||+ | Sbjct 371 PVDTNLIELDTNDDDIVFEDFARQRL#KGMKDDKEEEED 408 |
| human, Peptide, 418 aa | Query 360 PEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTD 397 | | + + |++ |||+|||| |#| + |||+ | Sbjct 371 PVDTNLIELDTNDDDIVFEDFARQRL#KGMEDDKEEEED 408 |
| Oryctolagus cuniculus | Query 360 PEDPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTD 397 | | + + |++ |||+|||| |#| + |||+ | Sbjct 363 PVDTNLIELDTNDDDIVFEDFARQRL#KGMKDDKEEEDD 400 |
| Ehrlichia ruminantium str. Welgevonden | Query 362 DPDTAKESFQDENFVFEEFARQNL#KDAGEYKEEKTDQE 399 | | + + |+||+|+ |+ + |+ #+| | |+ +||+ Sbjct 266 DEDLSDQDFEDESFIDEDLSDQDF#EDDGFTDEDLSDQD 303 |
[Site 2] ESFQDENFVF377-EEFARQNLKD
Phe377 Glu
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Glu368 | Ser369 | Phe370 | Gln371 | Asp372 | Glu373 | Asn374 | Phe375 | Val376 | Phe377 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Glu378 | Glu379 | Phe380 | Ala381 | Arg382 | Gln383 | Asn384 | Leu385 | Lys386 | Asp387 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| ATEVPFRLMHPQPEDPDTAKESFQDENFVFEEFARQNLKDAGEYKEEKTDQEAAMDE |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 120.00 | 6 | - |
| 2 | Bos taurus | 120.00 | 4 | put. S-antigen C-terminus |
| 3 | Contains: S-arrestin short form | 120.00 | 1 | ARRS_BOVIN S-arrestin (Retinal S-antigen) (48 kDa |
| 4 | Sus scrofa | 100.00 | 2 | S-antigen |
| 5 | Mus musculus | 88.20 | 6 | Retinal S-antigen |
| 6 | Canis familiaris | 88.20 | 4 | PREDICTED: arrestin, S-antigen |
| 7 | Rattus norvegicus | 88.20 | 3 | retinal S-antigen |
| 8 | Canis lupus familiaris | 85.90 | 1 | S-arrestin |
| 9 | Homo sapiens | 81.60 | 12 | arrestin |
| 10 | Macaca mulatta | 80.90 | 2 | PREDICTED: S-arrestin isoform 1 |
| 11 | Cavia porcellus | 80.10 | 1 | S-antigen |
| 12 | Xenopus tropicalis | 58.20 | 2 | S-antigen; retina and pineal gland (arrestin) |
| 13 | Gallus gallus | 57.00 | 2 | PREDICTED: hypothetical protein |
| 14 | Rana pipiens | 55.80 | 2 | ARRS_RANPI S-arrestin (Retinal S-antigen) (Rod pho |
| 15 | Rana catesbeiana | 55.50 | 2 | ARRS_RANCA S-arrestin (Retinal S-antigen) (Rod pho |
| 16 | Xenopus laevis | 53.90 | 8 | MGC84416 protein |
| 17 | Ambystoma tigrinum | 51.60 | 2 | AF203327_1 rod arrestin |
| 18 | Danio rerio | 44.30 | 3 | arrestin |
| 19 | Oryctolagus cuniculus | 43.90 | 1 | ARRB1_RABIT Beta-arrestin-1 (Arrestin beta 1) gb |
| 20 | human, Peptide, 418 aa | 43.90 | 1 | beta-arrestin 1 gb |
| 21 | human, Peptide, 410 aa | 43.90 | 1 | beta-arrestin 1 gb |
| 22 | Pan troglodytes | 43.10 | 3 | PREDICTED: arrestin beta 1 |
| 23 | Oryzias latipes | 42.70 | 2 | arrestin |
| 24 | Macaca fascicularis | 42.00 | 2 | unnamed protein product |
| 25 | Tetraodon nigroviridis | 40.80 | 1 | unnamed protein product |
| 26 | Gekko gecko | 40.40 | 1 | arrestin |
| 27 | Monodelphis domestica | 39.30 | 2 | PREDICTED: similar to calcium/calmodulin-dependent |
| 28 | Spermophilus tridecemlineatus | 37.00 | 1 | ARRC_SPETR Arrestin-C (Cone arrestin) (cArr) (Reti |
| 29 | Oncorhynchus mykiss | 36.20 | 3 | ARR1_ONCMY Arrestin, red cell isoform 1 (CARR) gb |
| 30 | Tribolium castaneum | 35.00 | 1 | PREDICTED: similar to CG5962-PA |
| 31 | Apis mellifera | 34.70 | 2 | PREDICTED: similar to Arrestin 2 CG5962-PA |
| 32 | Ehrlichia ruminantium str. Welgevonden | 33.10 | 1 | putative cell division protein FtsK |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 |
| Bos taurus | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 |
| Contains: S-arrestin short form | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||||| Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 |
| Sus scrofa | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 ||||||||||||||||+ | +|||||||||#||||||||||||| |||||||||| | Sbjct 350 ATEVPFRLMHPQPEDPE-AMDSFQDENFVF#EEFARQNLKDAGELKEEKTDQEAAAHE 405 |
| Mus musculus | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 |||||||||||||||| |||| |||| ||#|||||||||| || | | |++| || Sbjct 349 ATEVPFRLMHPQPEDP--AKESVQDENLVF#EEFARQNLKDTGENPEGKKDEDAGQDE 403 |
| Canis familiaris | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 |||||||||||||||| |||||||||| ||#|||||||||| | | | |+| |||| Sbjct 352 ATEVPFRLMHPQPEDPATAKESFQDENLVF#EEFARQNLKDFAE--EGKKDRE-AMDE 405 |
| Rattus norvegicus | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 |||||||||||||||| |||| |||| ||#|||||||||| || | | |++| || Sbjct 349 ATEVPFRLMHPQPEDP--AKESVQDENLVF#EEFARQNLKDTGENTEGKKDEDAGQDE 403 |
| Canis lupus familiaris | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 |||||||||||||||| |||||||| | ||#|||||||||| | | | |+| |||| Sbjct 352 ATEVPFRLMHPQPEDPATAKESFQDANLVF#EEFARQNLKDFAE--EGKKDRE-AMDE 405 |
| Homo sapiens | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAA 401 |||||||||||||||| ||||+|| | ||#||||| ||||||| +| | |+ | Sbjct 352 ATEVPFRLMHPQPEDP--AKESYQDANLVF#EEFARHNLKDAGEAEEGKRDKNDA 403 |
| Macaca mulatta | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQ 398 |||||||||||||||| ||||+|| | ||#||||| ||||||| +| | |+ Sbjct 352 ATEVPFRLMHPQPEDP--AKESYQDANLVF#EEFARHNLKDAGEAEEGKRDK 400 |
| Cavia porcellus | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKE-EKTDQEAAMDE 404 |||+||||||||||| |||+ |||| ||#|||||||||| || | +| ++||| || Sbjct 349 ATELPFRLMHPQPED--TAKDGLQDENLVF#EEFARQNLKDVGEGGEGKKEEEEAAPDE 404 |
| Xenopus tropicalis | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKD--AGEYKEEKTDQE 399 +||+|| |||| || +|||| ||++ ||#||||| ||| | |||+ | | Sbjct 344 STELPFILMHPNPE---SAKESEQDDDMVF#EEFARDQLKDELQAEEKEEEEDDE 394 |
| Gallus gallus | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEK 395 +||+|||||||+||+ ++| + | ||#|||||| ||| |+ +| | Sbjct 354 STELPFRLMHPKPEEKNSAGKD-GDAEMVF#EEFARQQLKDTGDEEENK 400 |
| Rana pipiens | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQE 399 +||+|| ||||+|+ |||| |+|+|||#|+||| +||| + +|++ ++| Sbjct 344 STELPFILMHPKPDSG--AKESEQEEDFVF#EDFARDHLKDELQPEEKEEEEE 393 |
| Rana catesbeiana | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQE 399 +||+|| ||||+|+ |||| |+|+|||#|+||| ||| + +|++ ++| Sbjct 344 STELPFILMHPKPDSG--AKESEQEEDFVF#EDFARDQLKDELQPEEKEEEEE 393 |
| Xenopus laevis | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKD--AGEYKEEKTDQE 399 +||+|| |||| || |||| ||++ ||#||||| || | |||+ | | Sbjct 344 STELPFILMHPNPESG--AKESEQDDDMVF#EEFARDPLKGELQAEEKEEEEDDE 395 |
| Ambystoma tigrinum | Query 348 ATEVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQEAAMDE 404 |||+|||||||+|| |+++ ||#|||||+ ||| + +++ |++ |+ Sbjct 347 ATEIPFRLMHPKPESAGD-----QEDDLVF#EEFAREQLKDELQPEDKDKDEDEDDDK 398 |
| Danio rerio | Query 350 EVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEE 394 |+||+||||+| | ||| +| ||#||| | || | ++| Sbjct 342 ELPFQLMHPKP---DAVKESEAEEEMVF#EEFKRTYLKGMPEDEDE 383 |
| Oryctolagus cuniculus | Query 348 ATEVPFRLMHPQPEDPDTAKE---------------SFQDENFVF#EEFARQNLKDAGEYK 392 | |+|| ||||+|++ +| |++ ||#|+|||| || + | Sbjct 336 AVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVF#EDFARQRLKGMKDDK 395 Query 393 EEKTD 397 ||+ | Sbjct 396 EEEDD 400 |
| human, Peptide, 418 aa | Query 348 ATEVPFRLMHPQPEDPDTAKE---------------SFQDENFVF#EEFARQNLKDAGEYK 392 | |+|| ||||+|++ +| |++ ||#|+|||| || + | Sbjct 344 AVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVF#EDFARQRLKGMEDDK 403 Query 393 EEKTD 397 ||+ | Sbjct 404 EEEED 408 |
| human, Peptide, 410 aa | Query 348 ATEVPFRLMHPQPEDPDTAKE---------------SFQDENFVF#EEFARQNLKDAGEYK 392 | |+|| ||||+|++ +| |++ ||#|+|||| || + | Sbjct 336 AVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVF#EDFARQRLKGMEDDK 395 Query 393 EEKTD 397 ||+ | Sbjct 396 EEEED 400 |
| Pan troglodytes | Query 348 ATEVPFRLMHPQPEDPDTA---------------KESFQDENFVF#EEFARQNLKDAGEYK 392 | |+|| ||||+|++ | + |++ ||#|+|||| || + | Sbjct 344 AVELPFTLMHPKPKEEPTLCLVPENETPVDTNLIELDTNDDDIVF#EDFARQRLKGMKDDK 403 Query 393 EEKTD 397 ||+ | Sbjct 404 EEEED 408 |
| Oryzias latipes | Query 350 EVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKD--AGEYKEEK 395 |||||||||+ || +|| ++ ||#||| | |+ ||+ +|+ Sbjct 341 EVPFRLMHPK---PDAVRESEMEDEMVF#EEFKRSYLRGIIAGDDDDEE 385 |
| Macaca fascicularis | Query 348 ATEVPFRLMHPQPEDPDTAKE---------------SFQDENFVF#EEFARQNLKDAGEYK 392 | |+|| ||||+|++ +| |++ ||#|+|||| || + | Sbjct 336 AVELPFTLMHPKPKEEPLHREVPENQTPVDTNLIELDTNDDDIVF#EDFARQRLKGMKDDK 395 Query 393 EEK 395 ||+ Sbjct 396 EEE 398 |
| Tetraodon nigroviridis | Query 350 EVPFRLMHPQP-EDPDTAKESFQDENFV----------F#EEFARQNLKDAGEYKEEKTDQ 398 |+|| ||||+| || | |+ | | + |#|+|||| | | |++ ++ Sbjct 507 ELPFTLMHPKPLEDVDADGEAQTDRNLIEFDTNDDDIIF#EDFARQRL--TGVVDEKQEEE 564 Query 399 EAA 401 ||| Query 399 EAA 401 |
| Gekko gecko | Query 350 EVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQE 399 ++| ||||+| | +||+ +|+ | #|||||| +| + ||| +++ Sbjct 287 DLPLVLMHPKPTD-NTARS---EEDIVI#EEFARQKIKGEPDDDEEKEEED 332 |
| Monodelphis domestica | Query 348 ATEVPFRLMHPQPEDPDTAKES-----------------FQDENFVF#EEFARQNLKDAGE 390 | |+|| ||||+| + +| |++ ||#|+|||| || + Sbjct 342 AVELPFTLMHPKPREEPVRREVPCTKYSTPQSLHLEQRVANDDDIVF#EDFARQRLKGMKD 401 Query 391 YKEEK 395 +||+ Sbjct 402 DQEEE 406 |
| Spermophilus tridecemlineatus | Query 350 EVPFRLMHPQPEDPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQE 399 |+| |+||+| ++|+ |+ | #|||||| +| || |++ +| Sbjct 346 ELPLTLIHPKP-----SQETTSSEDIVI#EEFARQ--EDGGEEKQKALAEE 388 |
| Oncorhynchus mykiss | Query 348 ATEVPFRLMHPQPED----------PDT-----------AKESF-QDENFVF#EEFARQNL 385 + |+|| ||||+| + ||+ || ||++|||#|+||| | Sbjct 337 SVELPFVLMHPKPTELPISRPQSAVPDSDPPIDTNLIEFETNSFSQDDDFVF#EDFARLRL 396 Query 386 KDAGEYKEE 394 | + |++ Sbjct 397 KGMADDKDD 405 |
| Tribolium castaneum | Query 349 TEVPFRLMHPQP-----EDPDTAK--------------ESFQDENFVF#EEFARQNLKDAG 389 |+|||+|+|| | | | | | | |+| ||#|+||| | | Sbjct 327 TDVPFKLLHPGPGAIEKEKPKTFKKMRSMEKARYANSYEHDDDDNIVF#EDFARFRLSRDG 386 |
| Apis mellifera | Query 349 TEVPFRLMHPQPEDPDTAKESFQ-------------------DENFVF#EEFARQNLKD 387 |+|||+|||| | + | + + |+| ||#|+||| | + Sbjct 346 TDVPFKLMHPAPGTAEKEKATLKKNKSIERTRYENSCYSNDDDDNIVF#EDFARLRLNE 403 |
| Ehrlichia ruminantium str. Welgevonden | Query 362 DPDTAKESFQDENFVF#EEFARQNLKDAGEYKEEKTDQE 399 | | + + |+||+|+ #|+ + |+ +| | |+ +||+ Sbjct 266 DEDLSDQDFEDESFID#EDLSDQDFEDDGFTDEDLSDQD 303 |
* References
[PubMed ID: 3478675] Shinohara T, Dietzschold B, Craft CM, Wistow G, Early JJ, Donoso LA, Horwitz J, Tao R, Primary and secondary structure of bovine retinal S antigen (48-kDa protein). Proc Natl Acad Sci U S A. 1987 Oct;84(20):6975-9.
[PubMed ID: 2950857] ... Yamaki K, Takahashi Y, Sakuragi S, Matsubara K, Molecular cloning of the S-antigen cDNA from bovine retina. Biochem Biophys Res Commun. 1987 Feb 13;142(3):904-10.
[PubMed ID: 7515057] ... Smith WC, Milam AH, Dugger D, Arendt A, Hargrave PA, Palczewski K, A splice variant of arrestin. Molecular cloning and localization in bovine retina. J Biol Chem. 1994 Jun 3;269(22):15407-10.
[PubMed ID: 3080338] ... Wistow GJ, Katial A, Craft C, Shinohara T, Sequence analysis of bovine retinal S-antigen. Relationships with alpha-transducin and G-proteins. FEBS Lett. 1986 Feb 3;196(1):23-8.
[PubMed ID: 2910351] ... Tsunasawa S, Shichi H, The amino acid sequence of S-antigen: N-terminus and uveitogenic peptides. Biochim Biophys Acta. 1989 Feb 2;994(2):191-3.
[PubMed ID: 2160981] ... Huppertz B, Weyand I, Bauer PJ, Ca2+ binding capacity of cytoplasmic proteins from rod photoreceptors is mainly due to arrestin. J Biol Chem. 1990 Jun 5;265(16):9470-5.
[PubMed ID: 9495348] ... Granzin J, Wilden U, Choe HW, Labahn J, Krafft B, Buldt G, X-ray crystal structure of arrestin from bovine rod outer segments. Nature. 1998 Feb 26;391(6670):918-21.
[PubMed ID: 10219246] ... Hirsch JA, Schubert C, Gurevich VV, Sigler PB, The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation. Cell. 1999 Apr 16;97(2):257-69.