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XSB1886 : calpain, small subunit 1 [Oryctolagus cuniculus]

[ CaMP Format ]

This entry is computationally expanded from SB0017

* Basic Information

OrganismOryctolagus cuniculus (rabbit)
Protein NamesCalpain small subunit 1; CSS1; Calcium-dependent protease small subunit 1; Calcium-dependent protease small subunit; CDPS; Calpain regulatory subunit; Calcium-activated neutral proteinase small subunit; CANP small subunit; calpain; small subunit 1
Gene NamesCAPNS1; CAPN4; calpain, small subunit 1
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001075733 NM_001082264 100009090 P06813 N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 266 aa

Average Mass: 28.239 kDa

Monoisotopic Mass: 28.221 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
TAT_signal 1. 6262.48.7
MazG 1. 82133-27.13.4
--- cleavage 139 ---
efhand 1. 14116918.40.03
efhand 2. 17119915.10.3
efhand 3. 2362638.22.7

3. Sequence Information

Fasta Sequence: XSB1886.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] PDLKTDGFGL139-DTCRSMVAVM

Leu139 Asp

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Pro130Asp131Leu132Lys133Thr134Asp135Gly136Phe137Gly138Leu139
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Asp140Thr141Cys142Arg143Ser144Met145Val146Ala147Val148Met149

Sequence conservation (by blast)

* References

[PubMed ID: 3038855] Minami Y, Emori Y, Kawasaki H, Suzuki K, E-F hand structure-domain of calcium-activated neutral protease (CANP) can bind Ca2+ ions. J Biochem. 1987 Apr;101(4):889-95.

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