XSB1918 : Receptor-type tyrosine-protein phosphatase-like N
[ CaMP Format ]
This entry is computationally expanded from SB0024
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | R-PTP-N; PTP IA-2 |
| Gene Names | Ptp35 |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 979 aa
Average Mass: 106.087 kDa
Monoisotopic Mass: 106.021 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Toxin_19 1. | 42 | 74 | -6.3 | 2.9 |
| TrmB 1. | 348 | 404 | -32.8 | 8.4 |
| FDX-ACB 1. | 474 | 550 | -53.8 | 2.9 |
| FCD 1. | 583 | 705 | -29.0 | 7.3 |
| --- cleavage 658 (inside FCD 583..705) --- | ||||
| Y_phosphatase 1. | 734 | 968 | 386.1 | 6e-113 |
3. Sequence Information
Fasta Sequence: XSB1918.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] PEPSRVSSVS658-SQFSDAAQAS
Ser658 
Ser
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Pro649 | Glu650 | Pro651 | Ser652 | Arg653 | Val654 | Ser655 | Ser656 | Val657 | Ser658 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser659 | Gln660 | Phe661 | Ser662 | Asp663 | Ala664 | Ala665 | Gln666 | Ala667 | Ser668 |
Sequence conservation (by blast)
* References
[PubMed ID: 7980563] Lu J, Notkins AL, Lan MS, Isolation, sequence and expression of a novel mouse brain cDNA, mIA-2, and its relatedness to members of the protein tyrosine phosphatase family. Biochem Biophys Res Commun. 1994 Oct 28;204(2):930-6.