XSB1930 : DMD [Homo sapiens]
[ CaMP Format ]
This entry is computationally expanded from SB0073
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | Dystrophin |
| Gene Names | DMD |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 655 aa
Average Mass: 75.767 kDa
Monoisotopic Mass: 75.720 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Spectrin 1. | 1 | 71 | 1.8 | 0.024 |
| KxDL 1. | 87 | 158 | -26.6 | 5.4 |
| Transposase_1 1. | 165 | 227 | -42.3 | 6.3 |
| --- cleavage 205 (inside Transposase_1 165..227) --- | ||||
| Spectrin 2. | 235 | 343 | 13.5 | 0.0025 |
| Spectrin 3. | 346 | 450 | 40.8 | 5.3e-09 |
| Spectrin 4. | 459 | 561 | 8.5 | 0.0065 |
| Spectrin 5. | 564 | 654 | 33.7 | 7.3e-07 |
3. Sequence Information
Fasta Sequence: XSB1930.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] TVMETVTTVT205-TREQILVKHA
Thr205 
Thr
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Thr196 | Val197 | Met198 | Glu199 | Thr200 | Val201 | Thr202 | Thr203 | Val204 | Thr205 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr206 | Arg207 | Glu208 | Gln209 | Ile210 | Leu211 | Val212 | Lys213 | His214 | Ala215 |
Sequence conservation (by blast)
* References
[PubMed ID: 3428261] Cross GS, Speer A, Rosenthal A, Forrest SM, Smith TJ, Edwards Y, Flint T, Hill D, Davies KE, Deletions of fetal and adult muscle cDNA in Duchenne and Becker muscular dystrophy patients. EMBO J. 1987 Nov;6(11):3277-83.