logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1961 : Proto-oncogene protein c-fos

[ CaMP Format ]

This entry is computationally expanded from SB0064

* Basic Information

OrganismMesocricetus auratus (golden hamster)
Protein NamesCellular oncogene fos
Gene NamesFOS
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
O88479 N/A N/A O88479 N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 381 aa

Average Mass: 41.020 kDa

Monoisotopic Mass: 40.994 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
DUF1602 1. 233-8.39.7
--- cleavage 90 ---
bZIP_1 1. 13519837.74.7e-08

3. Sequence Information

Fasta Sequence: XSB1961.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] LVSSVAPSQT90-RAPHPYGVPT

Thr90 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Leu81Val82Ser83Ser84Val85Ala86Pro87Ser88Gln89Thr90
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Arg91Ala92Pro93His94Pro95Tyr96Gly97Val98Pro99Thr100

Sequence conservation (by blast)

* References

[PubMed ID: 10326862] Sarabia SF, Liehr JG, Differential regulation of c-fos expression in estrogen-induced hamster renal tumors compared with kidney not due to creation of an estrogen-response element by point mutation in the gene's flanking sequence. Mol Carcinog. 1999 Apr;24(4):255-62.