XSB1973 : PREDICTED: similar to phosphoinositide-specific phospholipase C beta 1 isoform a [Macaca mulatta]
[ CaMP Format ]
This entry is computationally expanded from SB0008
* Basic Information
| Organism | Macaca mulatta (rhesus monkey) |
| Protein Names | similar to phosphoinositide-specific phospholipase C beta 1 isoform a |
| Gene Names | LOC718387; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 7 mRNAs, 75 ESTs, 5 Proteins |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 1216 aa
Average Mass: 138.586 kDa
Monoisotopic Mass: 138.498 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| Chitin_synth_1 1. | 92 | 181 | -119.6 | 3.6 |
| efhand_like 1. | 224 | 315 | 162.4 | 1.3e-45 |
| PI-PLC-X 1. | 318 | 468 | 326.6 | 4.8e-95 |
| PI-PLC-Y 1. | 539 | 656 | 297.8 | 2.3e-86 |
| C2 1. | 678 | 761 | 63.9 | 5.9e-16 |
| Big_4 1. | 835 | 897 | -7.0 | 1.7 |
| --- cleavage 880 (inside Big_4 835..897) --- |
| DUF1154 1. | 903 | 946 | 6.2 | 0.0036 |
| PLC-beta_C 1. | 997 | 1189 | 414.4 | 1.9e-121 |
3. Sequence Information
Fasta Sequence: XSB1973.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] TPKPPSQALH880-SQPAPGSVKA
His880 
Ser
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Thr871 | Pro872 | Lys873 | Pro874 | Pro875 | Ser876 | Gln877 | Ala878 | Leu879 | His880 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Ser881 | Gln882 | Pro883 | Ala884 | Pro885 | Gly886 | Ser887 | Val888 | Lys889 | Ala890 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
TPSEVRTTPAENGVNHTTSLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTI
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Macaca mulatta |
121.00 |
1 |
PREDICTED: similar to phosphoinositide-specific ph |
| 2 |
Homo sapiens |
117.00 |
7 |
phosphoinositide-specific phospholipase C beta 1 i |
| 3 |
Pan troglodytes |
117.00 |
1 |
PREDICTED: phosphoinositide-specific phospholipase |
| 4 |
N/A |
115.00 |
3 |
1 |
| 5 |
Bos taurus |
115.00 |
1 |
phosphoinositide-specific phospholipase C beta 1 |
| 6 |
Mus musculus |
111.00 |
7 |
PLCB1_MOUSE 1-phosphatidylinositol-4,5-bisphosphat |
| 7 |
Canis familiaris |
111.00 |
1 |
PREDICTED: similar to phosphoinositide-specific ph |
| 8 |
synthetic construct |
111.00 |
1 |
phospholipase C-beta1 |
| 9 |
Rattus norvegicus |
110.00 |
1 |
phospholipase C, beta 1 |
| 10 |
Monodelphis domestica |
102.00 |
2 |
PREDICTED: similar to phosphoinositide-specific ph |
| 11 |
Gallus gallus |
96.70 |
1 |
PREDICTED: similar to KIAA0581 protein |
| 12 |
Tetraodon nigroviridis |
36.60 |
2 |
unnamed protein product |
| 13 |
Xenopus laevis |
35.80 |
2 |
Unknown (protein for IMAGE:4743215) |
| 14 |
Giardia lamblia ATCC 50803 |
35.00 |
1 |
hypothetical protein GLP_38_74287_71057 |
| 15 |
Bovine herpesvirus 1 |
34.30 |
3 |
type 1 envelope glycoprotein C |
| 16 |
Neosartorya fischeri NRRL 181 |
32.30 |
1 |
conserved hypothetical protein |
Top-ranked sequences
| organism | matching |
|---|
| Macaca mulatta |
Query 851 TPSEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 851 TPSEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
|
| Homo sapiens |
Query 852 PSEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
||| |||||||||||||+|||||||||||#||||||||||||||||||||||||||||||
Sbjct 852 PSEARTTPAENGVNHTTTLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
|
| Pan troglodytes |
Query 852 PSEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
||| |||||||||||||+|||||||||||#||||||||||||||||||||||||||||||
Sbjct 907 PSEARTTPAENGVNHTTTLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 965
|
| N/A |
Query 852 PSEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
||| | |||||||||||||||||||||||#||||||||||||||||||||||||||||||
Sbjct 852 PSEARPTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
|
| Bos taurus |
Query 852 PSEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
||| | |||||||||||||||||||||||#||||||||||||||||||||||||||||||
Sbjct 852 PSEARPTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
|
| Mus musculus |
Query 852 PSEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
||| |||||||||||| || ||||||| |#||||||||||||||||||||||||||||||
Sbjct 852 PSETRTTPAENGVNHTASLAPKPPSQAPH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
|
| Canis familiaris |
Query 852 PSEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
||| | |||||||||||| |||||||||#||||||||||||||||||||||||||||||
Sbjct 846 PSEAGTNPAENGVNHTTSLAPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 904
|
| synthetic construct |
Query 852 PSEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
||| |||||||||||| || ||||||| |#||||||||||||||||||||||||||||||
Sbjct 852 PSETRTTPAENGVNHTASLAPKPPSQAPH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
|
| Rattus norvegicus |
Query 852 PSEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
||| |||||||||||| +| ||||||| |#||||||||||||||||||||||||||||||
Sbjct 852 PSETRTTPAENGVNHTATLAPKPPSQAPH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
|
| Monodelphis domestica |
Query 853 SEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
|| | ||||||||| || |||||| +|#|||||||||||||||||||||||+||||||
Sbjct 854 SEPRPAPAENGVNHTASLAPKPPSQVVH#SQPAPGSVKAPAKTEDLIQSVLTDVEAQTI 911
|
| Gallus gallus |
Query 853 SEVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQTI 910
|| | |||||||||| ||| || +| +|#||| || |||||||||||||||||||||||
Sbjct 1054 SEPRPTPAENGVNHTASLTSKPTTQVVH#SQPTPGLVKAPAKTEDLIQSVLTEVEAQTI 1111
|
| Tetraodon nigroviridis |
Query 857 TTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTE 895
| |||||++|| + ||||| # || | ++| |
Sbjct 561 TLPAENGLSHTPIIAPKPPSLG-G#LQPQPAELEAQTLEE 598
|
| Xenopus laevis |
Query 854 EVRTTPAENGVNHTTSLTPKPPSQALH#SQPAPGSVKAPAKTEDLIQSVLTEVEAQT 909
| + | | || | || | | # || | +|+||++ ++|+| + |
Sbjct 371 EPKVTSMETQEVHTESFTPSNPEQI--#------EVKTPPETDDLVEPIVTDVPSST 418
|
| Giardia lamblia ATCC 50803 |
Query 852 PSEVRTTPAENGVNHTTS-LTPKPPSQALH#SQP--APGSVKAPAKTEDLIQSVLTEVEAQ 908
|| | || | + + | |+| | |+|#+|| || |+| + || |+ + +
Sbjct 673 PSGVSPLPARNPMTSSMPPLPPRPKSAAIH#AQPPRAPSSLKPSSSCGDLSASLPVSLSPR 732
Query 909 T 909
|
Query 909 T 909
|
| Bovine herpesvirus 1 |
Query 851 TPSEVRTTPAENGVNHTTSL-TPKPPSQALH#SQPAPGSVKAPAKTED 896
||+ || ++ || + ||+||| + |# | | || ||
Sbjct 57 TPNSPDATPEDSTPGATTPVGTPEPPSVSEH#DPPVTNSTPPPAPPED 103
|
| Neosartorya fischeri NRRL 181 |
Query 862 NGVNHTTSLTPKPPSQALH#SQPA-PGSVKAPAKTE 895
|||+|| + || || | #| | ||| |+ |
Sbjct 100 NGVSHTITPTPTPPPSAGP#SSDAKPGSTSEPSSPE 134
|
