XSB1983 : autophagy-related 5-like [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0014
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | Autophagy protein 5; APG5-like; autophagy-related 5-like; autophagy 5-like |
| Gene Names | Atg5; Apg5l; autophagy-related 5 (yeast) |
| Gene Locus | 10 26.0 cM; chromosome 10 |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 275 aa
Average Mass: 32.402 kDa
Monoisotopic Mass: 32.381 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| APG5 1. | 79 | 272 | 370.7 | 2.7e-108 |
| --- cleavage 193 (inside APG5 79..272) --- | ||||
3. Sequence Information
Fasta Sequence: XSB1983.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] YIPFRIYQTT193-TERPFIQKLF
Thr193 
Thr
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Tyr184 | Ile185 | Pro186 | Phe187 | Arg188 | Ile189 | Tyr190 | Gln191 | Thr192 | Thr193 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr194 | Glu195 | Arg196 | Pro197 | Phe198 | Ile199 | Gln200 | Lys201 | Leu202 | Phe203 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| QFWAINRKLMEYPPEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLREVC |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 130.00 | 2 | autophagy-related 5-like |
| 2 | Rattus norvegicus | 128.00 | 1 | ATG5_RAT Autophagy protein 5 emb |
| 3 | Sus scrofa | 127.00 | 1 | APG5 autophagy 5-like |
| 4 | Canis familiaris | 125.00 | 3 | PREDICTED: similar to Autophagy protein 5-like (AP |
| 5 | Homo sapiens | 125.00 | 2 | APG5 autophagy 5-like |
| 6 | Macaca mulatta | 125.00 | 2 | PREDICTED: ATG5 autophagy related 5 homolog (S. ce |
| 7 | Pongo pygmaeus | 125.00 | 1 | ATG5_PONPY Autophagy protein 5 (APG5-like) emb |
| 8 | Pan troglodytes | 125.00 | 1 | PREDICTED: hypothetical protein LOC462905 isoform |
| 9 | Bos taurus | 123.00 | 2 | autophagy protein 5 |
| 10 | Monodelphis domestica | 121.00 | 1 | PREDICTED: similar to Autophagy protein 5 |
| 11 | Gallus gallus | 118.00 | 1 | APG5 autophagy 5-like |
| 12 | Xenopus laevis | 108.00 | 2 | autophagy protein 5 |
| 13 | Ictalurus punctatus | 107.00 | 1 | autophagy protein 5 |
| 14 | Xenopus tropicalis | 107.00 | 1 | APG5 autophagy 5-like |
| 15 | Gasterosteus aculeatus | 105.00 | 1 | autophagy protein 5 |
| 16 | Oryzias latipes | 104.00 | 1 | autophagy protein 5 |
| 17 | Pimephales promelas | 103.00 | 1 | autophagy protein 5 |
| 18 | Tetraodon nigroviridis | 101.00 | 2 | autophagy protein 5 |
| 19 | Danio rerio | 100.00 | 2 | APG5 autophagy 5-like protein isoform 2 |
| 20 | Apis mellifera | 65.90 | 1 | PREDICTED: similar to APG5 autophagy 5-like protei |
| 21 | Callinectes sapidus | 61.20 | 1 | autophagy protein 5 |
| 22 | Tribolium castaneum | 59.70 | 1 | PREDICTED: similar to CG1643-PA |
| 23 | Aedes aegypti | 55.10 | 1 | Autophagy-specific protein, putative |
| 24 | Anopheles gambiae str. PEST | 54.30 | 1 | ENSANGP00000012467 |
| 25 | Drosophila erecta | 53.90 | 1 | autophagy protein 5 |
| 26 | Drosophila yakuba | 53.90 | 1 | autophagy protein 5 |
| 27 | Drosophila ananassae | 52.80 | 1 | autophagy protein 5 |
| 28 | Drosophila simulans | 52.40 | 1 | autophagy protein 5 |
| 29 | Drosophila melanogaster | 52.40 | 1 | Autophagy-specific gene 5 CG1643-PA |
| 30 | Drosophila persimilis | 51.20 | 1 | autophagy protein 5 |
| 31 | Drosophila pseudoobscura | 51.20 | 1 | GA14069-PA |
| 32 | Drosophila grimshawi | 50.40 | 1 | autophagy protein 5 |
| 33 | Strongylocentrotus purpuratus | 48.50 | 1 | PREDICTED: similar to autophagy protein 5, partial |
| 34 | Drosophila virilis | 48.10 | 1 | autophagy protein 5 |
| 35 | Drosophila mojavensis | 48.10 | 1 | autophagy protein 5 |
| 36 | Caenorhabditis briggsae | 40.80 | 1 | Hypothetical protein CBG22152 |
| 37 | Caenorhabditis elegans | 40.00 | 1 | ATG (AuTophaGy) Related family member (atgr-5) |
| 38 | Schistosoma japonicum | 39.30 | 1 | SJCHGC03143 protein |
| 39 | Ciona intestinalis | 36.60 | 1 | autophagy protein 5 |
| 40 | Ciona savignyi | 35.80 | 1 | autophagy protein 5 |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 |
| Rattus norvegicus | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||| ||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 164 QFWTINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 |
| Sus scrofa | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||| |||||+||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 164 QFWTINRKLIEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 |
| Canis familiaris | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||||||||||| ||||||||||||||||#||||||||||||||||||||||||||+||| Sbjct 164 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 223 |
| Homo sapiens | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||||||||||| ||||||||||||||||#||||||||||||||||||||||||||+||| Sbjct 164 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 223 |
| Macaca mulatta | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||||||||||| ||||||||||||||||#||||||||||||||||||||||||||+||| Sbjct 164 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 223 |
| Pongo pygmaeus | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||||||||||| ||||||||||||||||#||||||||||||||||||||||||||+||| Sbjct 164 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 223 |
| Pan troglodytes | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||||||||||| ||||||||||||||||#||||||||||||||||||||||||||+||| Sbjct 126 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLKEVC 185 |
| Bos taurus | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||||||||||| ||||||||||||||||#|||||||||||||+ |||||||||||+||| Sbjct 164 QFWAINRKLMEYPAEENGFRYIPFRIYQTT#TERPFIQKLFRPVSTDGQLHTLGDLLKEVC 223 |
| Monodelphis domestica | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||||||||||| |+|||||||||||| |#|||||||||||||| |||||||||||+||| Sbjct 164 QFWAINRKLMEYPAEDNGFRYIPFRIYQAT#TERPFIQKLFRPVATDGQLHTLGDLLKEVC 223 |
| Gallus gallus | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 |||||||||||||||++||||||||||| |#||||||||||||+|+ ||||||||||++|| Sbjct 164 QFWAINRKLMEYPPEDSGFRYIPFRIYQAT#TERPFIQKLFRPIASGGQLHTLGDLLKDVC 223 |
| Xenopus laevis | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 |||||||||||+ ||+ |||||||||||| # +|||||||||||| ||+ ||||||+||+| Sbjct 165 QFWAINRKLMEFSPEDGGFRYIPFRIYQTI#NDRPFIQKLFRPVANDGRPHTLGDLIREIC 224 |
| Ictalurus punctatus | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||||||||||| || |||||||||||| #++|||||| ||||+++| |||||||+|+| Sbjct 164 QFWAINRKLMEYPTEEGGFRYIPFRIYQTL#SDRPFIQKPFRPVSSEGHAHTLGDLLKEMC 223 |
| Xenopus tropicalis | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||||||||| |||+ ||||||||||| # ||||||||||||| ||+ +|||||+|||| Sbjct 164 QFWAINRKLMEVPPEDGGFRYIPFRIYQAI#NERPFIQKLFRPVANDGRPYTLGDLIREVC 223 |
| Gasterosteus aculeatus | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 |||||||||||| |+ |||||||||||||#++|||||||||| + +| |||||||+|+| Sbjct 164 QFWAINRKLMEYSSEDGGFRYIPFRIYQTT#SDRPFIQKLFRPTSPEGSAHTLGDLLKEMC 223 |
| Oryzias latipes | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||+|||||||| || |||||||||||||# +|||||+|||||+ +| ||| |||+|+| Sbjct 164 QFWAMNRKLMEYPTEEGGFRYIPFRIYQTT#NDRPFIQRLFRPVSTEGNPHTLFDLLKEMC 223 |
| Pimephales promelas | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+|||||||| |+ |||||||||||||#++|||||||||||+|+| ||||||+|+ Sbjct 164 QFWAMNRKLMEYPTEDGGFRYIPFRIYQTT#SDRPFIQKLFRPVSAEGHALTLGDLLKEL 222 |
| Tetraodon nigroviridis | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREVC 223 ||||+||||||| || |||||||||||||# +|||||+|||||+ +| ||| |||+|+| Sbjct 164 QFWAMNRKLMEYSTEEGGFRYIPFRIYQTT#NDRPFIQRLFRPVSTEGNPHTLFDLLKEMC 223 |
| Danio rerio | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+|||||||| || |||||||||||| #++||||| |||||+++|| ||||||+|+ Sbjct 166 QFWAMNRKLMEYPTEEGGFRYIPFRIYQTM#SDRPFIQTLFRPVSSEGQALTLGDLLKEL 224 |
| Apis mellifera | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 |||++|||||| | ||+||||| | |#+| ++||| +|| +|| || || || Sbjct 167 QFWSVNRKLMEASNIEEGFKYIPFRCY--T#SEDKYVQKLVKPVNEEGQRKTLRHLLNEV 223 |
| Callinectes sapidus | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLRE 221 ||||||||||| ||| ||++||||++ # + | ||+| ||+ ||+ || ||| | Sbjct 166 QFWAINRKLMESTPEE-GFKFIPFRLH-CP#FQAP-IQRLIRPLTEDGRRVTLADLLME 220 |
| Tribolium castaneum | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+|||||| |+ |+||||+ | # + + ||| +|| ||+ || ||+ |+ Sbjct 167 QFWAVNRKLMEVSQEQEHFKYIPFKCY---#LDDGYRQKLIKPVDEDGRRKTLQDLINEM 222 |
| Aedes aegypti | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLRE 221 ||||+||+||| |+++||++|| | | # + + ||| | || || ||| + Sbjct 165 QFWAVNRRLMEPIPDQDGFKHIPVRCY--A#EDGSYQQKLVAPSTETGQKRTLQDLLED 220 |
| Anopheles gambiae str. PEST | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLL 219 ||||+||+||| |+++||++|| | | # + + ||| | | || | ||| Sbjct 165 QFWAVNRRLMEPIPDQDGFKHIPVRCY--A#EDGTYQQKLVAPSTASGQKRLLQDLL 218 |
| Drosophila erecta | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+||+||| ++ |+ || ||| | # + + ||| |++ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYGDQESFKNIPLRIY-TD#DDFTYTQKLISPISEGGQKKSLADLMAEL 223 |
| Drosophila yakuba | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+||+||| ++ |+ || ||| | # + + ||| |++ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYADQESFKNIPLRIY-TD#DDFTYSQKLISPISEGGQKKSLADLMAEL 223 |
| Drosophila ananassae | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+||+||| ++ |++|| |+| # + + ||| |+ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYGDQESFKHIPLRLY-AD#DDFTYTQKLISPITESGQKKSLADLMAEL 223 |
| Drosophila simulans | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+||+||| + |+ || ||| | # + + ||| |++ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYGDLESFKNIPLRIY-TD#DDFTYTQKLISPISVGGQKKSLADLMAEL 223 |
| Drosophila melanogaster | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+||+||| + |+ || ||| | # + + ||| |++ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYGDLESFKNIPLRIY-TD#DDFTYTQKLISPISVGGQKKSLADLMAEL 223 |
| Drosophila persimilis | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+||+||| ++ |+ || |+| # + + ||| |++ || +| ||+ |+ Sbjct 165 QFWAVNRRLMEPYGDQESFKNIPVRLY-ND#DDFTYTQKLISPISESGQKKSLADLMAEL 222 |
| Drosophila pseudoobscura | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+||+||| ++ |+ || |+| # + + ||| |++ || +| ||+ |+ Sbjct 166 QFWAVNRRLMEPYGDQESFKNIPVRLY-ND#DDFTYTQKLISPISESGQKKSLADLMAEL 223 |
| Drosophila grimshawi | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+||+||| ++ |+ || | | # + ++||| |++ || | ||+ |+ Sbjct 164 QFWAVNRRLMEPYSDQESFKNIPIRFYY-D#DDFTYMQKLITPLSQSGQKKNLADLMAEL 221 |
| Strongylocentrotus purpuratus | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLRE 221 ||| ||+||| + |++|||+|+| # |+ |+||+|| +|+ || ||+| Sbjct 139 QFWTTNRRLMERL-NNDPFKFIPFKIFQVP#-EKLHTQRLFKPVNDEGEPRTLRALLKE 194 |
| Drosophila virilis | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ||||+||+||| ++ |+ || | | # + ++||| |+ || | ||+ |+ Sbjct 166 QFWAVNRRLMEPYSDQESFKNIPVRFYY-D#DDFTYMQKLITPLNESGQKKNLADLMIEL 223 |
| Drosophila mojavensis | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 |||||||+||| ++ |+ || | | # + ++||| |+ || | ||+ |+ Sbjct 166 QFWAINRRLMEPYNDQESFKNIPVRFYY-D#DDFTYMQKLISPLNEAGQKKNLADLMAEL 223 |
| Caenorhabditis briggsae | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 ++| + +|||+ | + | ++| |+| # +|| | | || | |+|| + |+ Sbjct 165 EYWGMIQKLMD-PKDGKDFLHVPLRVY--V#KNQPFKQALITVKHPDGSLRTIGDAVSEI 220 |
| Caenorhabditis elegans | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRPVAADGQLHTLGDLLREV 222 +|| | +|||| | | | +|| |+| # + | | | || | |+|+ + +| Sbjct 163 EFWTIVQKLME-TSEGNEFAHIPLRVY--V#KNQAFKQALITAKHPDGSLRTIGEAVSDV 218 |
| Schistosoma japonicum | Query 164 QFWAINRKLME--------YPPEE------------------------NGFRYIPFRIYQ 191 |||+|| |||| | || ||||| |+| Sbjct 66 QFWSINSKLMEPLPYNTKDLPSEEIPISEIPENKSKSANLDNISSSRCKTFRYIPCRLY- 124 Query 192 TT#TERP------FIQKLFRPVAADGQLHTLGDLLR 220 #+| | | ||| ||+ || | +| | +| Sbjct 125 CV#SENPNSAPSGFTQKLIRPLNDDGSLISLQDAIR 159 |
| Ciona intestinalis | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRP 205 +||+||++ | + ||+|| |+| # + |||||+| Sbjct 164 EFWSINKQFMSGFETTDYFRFIPLRVY---#FQNRIIQKLFKP 202 |
| Ciona savignyi | Query 164 QFWAINRKLMEYPPEENGFRYIPFRIYQTT#TERPFIQKLFRP 205 +||+||++ | || || ||| # + |||||+| Sbjct 162 EFWSINKQFMTDYEHSECFRCIPIRIY---#FQNQIIQKLFKP 200 |
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