XSB2056 : microtubule-associated protein 2 [Rattus norvegicus]
[ CaMP Format ]
This entry is computationally expanded from SB0057
* Basic Information
| Organism | Rattus norvegicus (Norway rat) |
| Protein Names | Microtubule-associated protein; microtubule-associated protein 2 |
| Gene Names | Map2; Mtap2; microtubule-associated protein 2 |
| Gene Locus | 9q32; chromosome 9 |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 1825 aa
Average Mass: 198.566 kDa
Monoisotopic Mass: 198.446 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| RII_binding_1 1. | 86 | 103 | 19.2 | 0.017 |
| --- cleavage 99 (inside RII_binding_1 86..103) --- | ||||
| MAP2_projctn 1. | 374 | 1507 | 3094.6 | 0 |
| Tubulin-binding 1. | 1658 | 1689 | 64.3 | 4.4e-16 |
| Tubulin-binding 2. | 1690 | 1720 | 66.0 | 1.4e-16 |
| Tubulin-binding 3. | 1721 | 1752 | 55.1 | 2.6e-13 |
3. Sequence Information
Fasta Sequence: XSB2056.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] VSARIVQVVT99-AEAVAVLKGE
Thr99 
Ala
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Val90 | Ser91 | Ala92 | Arg93 | Ile94 | Val95 | Gln96 | Val97 | Val98 | Thr99 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ala100 | Glu101 | Ala102 | Val103 | Ala104 | Val105 | Leu106 | Lys107 | Gly108 | Glu109 |
Sequence conservation (by blast)
* References
[PubMed ID: 19009287] Leterrier JF, Kurachi M, Tashiro T, Janmey PA, MAP2-mediated in vitro interactions of brain microtubules and their modulation by cAMP. Eur Biophys J. 2009 Apr;38(4):381-93. Epub 2008 Nov 14.