logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2057 : microtubule-associated protein 2, smallest isoform MAP2c - rat

[ CaMP Format ]

This entry is computationally expanded from SB0057

* Basic Information

OrganismRattus norvegicus (Norway rat)
Protein Namesmicrotubule-associated protein 2; smallest isoform MAP2c
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
JC7923 N/A N/A N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 467 aa

Average Mass: 49.300 kDa

Monoisotopic Mass: 49.270 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
RII_binding_1 1. 8610319.20.017
--- cleavage 99 (inside RII_binding_1 86..103) ---
Tubulin-binding 1. 30033164.34.4e-16
Tubulin-binding 2. 33236266.01.4e-16
Tubulin-binding 3. 36339455.12.6e-13

3. Sequence Information

Fasta Sequence: XSB2057.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] VSARIVQVVT99-AEAVAVLKGE

Thr99 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Val90Ser91Ala92Arg93Ile94Val95Gln96Val97Val98Thr99
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala100Glu101Ala102Val103Ala104Val105Leu106Lys107Gly108Glu109

Sequence conservation (by blast)

* References

[PubMed ID: 12535652] Malmendal A, Halpain S, Chazin WJ, Nascent structure in the kinase anchoring domain of microtubule-associated protein 2. Biochem Biophys Res Commun. 2003 Jan 31;301(1):136-42.