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XSB2110 : gamma-filamin [Homo sapiens]

[ CaMP Format ]

This entry is computationally expanded from SB0092

* Basic Information

OrganismHomo sapiens (human)
Protein NamesFilamin-C; Gamma-filamin; Filamin-2; Protein FLNc; Actin-binding-like protein; ABP-L; ABP-280-like protein; similar to actin-binding protein
Gene NamesABPL; ABPL, FLN2; FLN2
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAD12245 N/A N/A Q14315 N/A N/A N/A hsa:2318

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 2705 aa

Average Mass: 288.901 kDa

Monoisotopic Mass: 288.721 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
CH 1. 17122109.89.2e-30
CH 2. 14024298.91.8e-26
Filamin 1. 252345128.22.6e-35
Filamin 2. 352445124.53.4e-34
Filamin 3. 451542134.04.7e-37
Filamin 4. 548635117.83.6e-32
Filamin 5. 644735146.11.1e-40
Filamin 6. 741838142.01.8e-39
Filamin 7. 844937123.56.7e-34
Filamin 8. 9431033108.22.8e-29
Filamin 9. 10391126151.52.5e-42
Filamin 10. 11321221149.31.1e-41
Filamin 11. 12271321124.34e-34
Filamin 12. 13271414156.48.5e-44
Filamin 13. 14201510147.15.5e-41
Filamin 14. 15161607140.84.4e-39
Filamin 15. 16131711101.62.7e-27
Filamin 16. 1754183121.70.00014
Filamin 17. 18361923156.48.4e-44
Filamin 18. 1924201019.20.00024
Filamin 19. 20182105149.69.6e-42
Filamin 20. 2196228341.04.9e-09
Filamin 21. 22912378127.06.1e-35
Filamin 22. 2385247386.78.4e-23
Filamin 23. 24822569123.19.1e-34
--- cleavage 2606 ---
Filamin 24. 26122701116.68e-32

3. Sequence Information

Fasta Sequence: XSB2110.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1V05 (X-ray; 143 A; A=2633-2725), 2D7M (NMR; -; A=1536-1637), 2D7N (NMR; -; A=1782-1861), 2D7O (NMR; -; A=1856-1953), 2D7P (NMR; -; A=2405-2500), 2D7Q (NMR; -; A=2502-2599), 2NQC (X-ray; 205 A; A=2495-2598)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] SSSSRGSSYS2606-SIPKFSSDAS

Ser2606 Ser

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ser2597Ser2598Ser2599Ser2600Arg2601Gly2602Ser2603Ser2604Tyr2605Ser2606
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ser2607Ile2608Pro2609Lys2610Phe2611Ser2612Ser2613Asp2614Ala2615Ser2616

Sequence conservation (by blast)

* References

None.