XSB2129 : amphiphysin I variant NT2 [Homo sapiens]
[ CaMP Format ]
This entry is computationally expanded from SB0093
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | amphiphysin I variant NT2 |
| Gene Names | AMPH |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein |
Entrez Nucleotide |
Entrez Gene |
UniProt |
OMIM |
HGNC |
HPRD |
KEGG |
| AAM44811 |
N/A |
N/A |
Q8NFL3 |
N/A |
N/A |
N/A |
hsa: |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 385 aa
Average Mass: 43.754 kDa
Monoisotopic Mass: 43.726 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| BAR 1. | 13 | 233 | 288.1 | 1.9e-83 |
3. Sequence Information
Fasta Sequence: XSB2129.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] FEDNFVPEIS336-VTTPSQNEVP
Ser336 
Val
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Phe327 | Glu328 | Asp329 | Asn330 | Phe331 | Val332 | Pro333 | Glu334 | Ile335 | Ser336 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Val337 | Thr338 | Thr339 | Pro340 | Ser341 | Gln342 | Asn343 | Glu344 | Val345 | Pro346 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
PPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEV
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Homo sapiens |
125.00 |
18 |
AF498097_1 amphiphysin I variant NT2 |
| 2 |
Pan troglodytes |
125.00 |
6 |
PREDICTED: amphiphysin |
| 3 |
Canis familiaris |
125.00 |
2 |
PREDICTED: similar to Amphiphysin |
| 4 |
synthetic construct |
125.00 |
1 |
amphiphysin |
| 5 |
Macaca mulatta |
123.00 |
4 |
PREDICTED: amphiphysin (Stiff-Man syndrome with br |
| 6 |
Bos taurus |
123.00 |
2 |
PREDICTED: similar to Amphiphysin (Stiff-Man syndr |
| 7 |
Rattus norvegicus |
117.00 |
3 |
amphiphysin 1 |
| 8 |
Monodelphis domestica |
117.00 |
2 |
PREDICTED: similar to cytokine receptor common gam |
| 9 |
Mus musculus |
116.00 |
4 |
amphiphysin |
| 10 |
Gallus gallus |
112.00 |
1 |
amphiphysin (Stiff-Man syndrome with breast cancer |
| 11 |
Xenopus tropicalis |
110.00 |
3 |
Unknown (protein for MGC:122074) |
| 12 |
Xenopus laevis |
108.00 |
1 |
hypothetical protein LOC432150 |
| 13 |
Danio rerio |
74.70 |
1 |
amphiphysin |
| 14 |
Lampetra fluviatilis |
64.70 |
1 |
amphiphysin |
| 15 |
N/A |
59.30 |
1 |
A |
| 16 |
Tetraodon nigroviridis |
55.80 |
1 |
unnamed protein product |
Top-ranked sequences
| organism | matching |
|---|
| Homo sapiens |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
|
| Pan troglodytes |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
|
| Canis familiaris |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
|
| synthetic construct |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
|
| Macaca mulatta |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
||||||||||||+|||||||||||||||||#||||||||||||||||||||||||||||||
Sbjct 304 PPLPKVTPTKELRQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 363
|
| Bos taurus |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
||||||||||||||||||||||||||||||#||||||||+|||||||||||||||||||+|
Sbjct 204 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEIPEVKKEETLLDLDFDPFKPDV 263
|
| Rattus norvegicus |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
||||||||||||||||||+||||||||||+#||||||||| ||||||||||||||||||+|
Sbjct 304 PPLPKVTPTKELQQENIINFFEDNFVPEIN#VTTPSQNEVLEVKKEETLLDLDFDPFKPDV 363
|
| Monodelphis domestica |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
||||||||||||||||||| ||||||||||#||||||||||| ||||+|||||||||||+|
Sbjct 304 PPLPKVTPTKELQQENIISLFEDNFVPEIS#VTTPSQNEVPEQKKEESLLDLDFDPFKPDV 363
|
| Mus musculus |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
||||||||||||+|||||+||||||||||+#||||||||| ||||||||||||||||||+|
Sbjct 304 PPLPKVTPTKELKQENIINFFEDNFVPEIN#VTTPSQNEVLEVKKEETLLDLDFDPFKPDV 363
|
| Gallus gallus |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
|||||+||||||||||||+ |+|||||||+#||||||||+|| || |+|||||||||||||
Sbjct 304 PPLPKLTPTKELQQENIINLFDDNFVPEIN#VTTPSQNEIPETKKVESLLDLDFDPFKPEV 363
|
| Xenopus tropicalis |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPE 365
|||||+||+||||||||||||||||||||+#|||||||| | ||||+||||||||||||
Sbjct 305 PPLPKLTPSKELQQENIISFFEDNFVPEIN#VTTPSQNEAVEEKKEESLLDLDFDPFKPE 363
|
| Xenopus laevis |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKP 364
|||||+||+||||||||||||||||||||+#|||||||| | ||||+|||||||||||
Sbjct 309 PPLPKLTPSKELQQENIISFFEDNFVPEIN#VTTPSQNEAVEEKKEESLLDLDFDPFKP 366
|
| Danio rerio |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPE 365
|| ||||||+||||| || |+ | ||||#||+| || | |+|||||||||||+
Sbjct 304 PPPPKVTPTRELQQEQIIDLFDGGF-PEIS#VTSPQPNERP----GESLLDLDFDPFKPD 357
|
| Lampetra fluviatilis |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPE 365
|| ||+||+||+||| | | |+|||||+ |# + |++ | | +|||+|||| ||+
Sbjct 303 PPPPKLTPSKEVQQEAIFSLFDDNFVPDFS#-SAPAE---AAKKDEGSLLDIDFDPLKPD 357
|
| N/A |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQ 342
|| || ||+||++|| |+| ||| ||||||#||||||
Sbjct 42 PPPPKHTPSKEVKQEQILSLFEDTFVPEIS#VTTPSQ 77
|
| Tetraodon nigroviridis |
Query 307 PPLPKVTPTKELQQENIISFFEDNFVPEIS#VTTPSQNEVPEVKKEETLLDLDFDPFKPEV 366
|| |||||+|+++ |||++ |+ |+||#||+|++ + | | +|||+| | | |
Sbjct 212 PPPPKVTPSKDMKAENIVNLFDAAAAPDIS#VTSPTEFDRPAV---SSLLDVDLDSFTSTV 268
|
* References
[PubMed ID: 12023042] Terada Y, Tsutsui K, Sano K, Hosoya O, Ohtsuki H, Tokunaga A, Tsutsui K, Novel splice variants of amphiphysin I are expressed in retina. FEBS Lett. 2002 May 22;519(1-3):185-90.
