XSB2135 : amphiphysin [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0093
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | amphiphysin |
| Gene Names | Amph; Amph1; amphiphysin |
| Gene Locus | 13 10.0 cM; chromosome 13 |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| NP_778172 | NM_175007 | 218038 | Q7TQF7 | N/A | N/A | N/A | mmu:218038 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 686 aa
Average Mass: 75.013 kDa
Monoisotopic Mass: 74.967 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| BAR 1. | 13 | 233 | 290.4 | 4e-84 |
| --- cleavage 333 --- | ||||
| DUF2510 1. | 416 | 445 | -16.5 | 7.4 |
| SH3_1 1. | 616 | 685 | 22.4 | 0.00026 |
3. Sequence Information
Fasta Sequence: XSB2135.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] FEDNFVPEIN333-VTTPSQNEVL
Asn333 
Val
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Phe324 | Glu325 | Asp326 | Asn327 | Phe328 | Val329 | Pro330 | Glu331 | Ile332 | Asn333 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Val334 | Thr335 | Thr336 | Pro337 | Ser338 | Gln339 | Asn340 | Glu341 | Val342 | Leu343 |
Sequence conservation (by blast)
* References
[PubMed ID: 18761055] Choudhury M, Kleiner O, Chung R, Barden L, Morgan L, Patel TR, Staddon JM, Amphiphysin I phosphorylation on residue threonine 260 in a pentylenetetrazole-induced seizure model. Neurosci Lett. 2008 Oct 31;444(3):245-9. Epub 2008 Aug 23.