logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2138 : unnamed protein product [Homo sapiens]

[ CaMP Format ]

This entry is computationally expanded from SB0097

* Basic Information

OrganismHomo sapiens (human)
Protein NamesInsulin-like growth factor-binding protein 2; IGF-binding protein 2; IGFBP-2; IBP-2
Gene NamesBP2, IBP2; BP2; IBP2
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
CAA34373 N/A N/A IBP2_HUMAN N/A 5471 N/A hsa:3485

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 328 aa

Average Mass: 35.084 kDa

Monoisotopic Mass: 35.061 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
IGFBP 1. 45119107.64.2e-29
--- cleavage 202 ---
Thyroglobulin_1 1. 230309150.45.5e-42

3. Sequence Information

Fasta Sequence: XSB2138.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 2H7T (NMR; -; A=223-328)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] VFREKVTEQH202-RQMGKGGKHH

His202 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Val193Phe194Arg195Glu196Lys197Val198Thr199Glu200Gln201His202
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Arg203Gln204Met205Gly206Lys207Gly208Gly209Lys210His211His212

Sequence conservation (by blast)

* References

[PubMed ID: 2479552] Binkert C, Landwehr J, Mary JL, Schwander J, Heinrich G, Cloning, sequence analysis and expression of a cDNA encoding a novel insulin-like growth factor binding protein (IGFBP-2). EMBO J. 1989 Sep;8(9):2497-502.