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XSB2140 : insulin-like growth factor binding protein 2, 36kDa [Bos taurus]

[ CaMP Format ]

This entry is computationally expanded from SB0097

* Basic Information

OrganismBos taurus (cattle)
Protein NamesInsulin-like growth factor-binding protein 2; IGF-binding protein 2; IGFBP-2; IBP-2; insulin-like growth factor binding protein 2; 36kDa
Gene NamesIGFBP2; insulin-like growth factor binding protein 2, 36kDa
Gene Locus2; chromosome 2
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_776980 NM_174555 282260 IBP2_BOVIN N/A N/A N/A bta:282260

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 317 aa

Average Mass: 34.015 kDa

Monoisotopic Mass: 33.993 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
IGFBP 1. 3910888.72.1e-23
--- cleavage 191 ---
Thyroglobulin_1 1. 219298150.45.5e-42

3. Sequence Information

Fasta Sequence: XSB2140.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] VFREKVTEQH191-RQMGKGGKHH

His191 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Val182Phe183Arg184Glu185Lys186Val187Thr188Glu189Gln190His191
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Arg192Gln193Met194Gly195Lys196Gly197Gly198Lys199His200His201

Sequence conservation (by blast)

* References

[PubMed ID: 14561651] Ravelich SR, Breier BH, Reddy S, Keelan JA, Wells DN, Peterson AJ, Lee RS, Insulin-like growth factor-I and binding proteins 1, 2, and 3 in bovine nuclear transfer pregnancies. Biol Reprod. 2004 Feb;70(2):430-8. Epub 2003 Oct 15.

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