XSB2141 : PREDICTED: similar to Insulin-like growth factor binding protein 2 precursor (IGFBP-2) (IBP-2) (IGF-binding protein 2) [Canis familiaris]
[ CaMP Format ]
This entry is computationally expanded from SB0097
* Basic Information
| Organism | Canis lupus familiaris (dog) |
| Protein Names | similar to Insulin-like growth factor binding protein 2 precursor (IGFBP-2) (IBP-2) (IGF-binding protein 2) |
| Gene Names | LOC488516; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 1 Protein |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 271 aa
Average Mass: 29.900 kDa
Monoisotopic Mass: 29.880 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| IGFBP 1. | 12 | 62 | 58.1 | 3.5e-14 |
| --- cleavage 145 --- |
| Thyroglobulin_1 1. | 173 | 252 | 148.4 | 2.1e-41 |
3. Sequence Information
Fasta Sequence: XSB2141.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] VFREKVTEQH145-RQMGKGGKHH
His145 
Arg
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Val136 | Phe137 | Arg138 | Glu139 | Lys140 | Val141 | Thr142 | Glu143 | Gln144 | His145 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Arg146 | Gln147 | Met148 | Gly149 | Lys150 | Gly151 | Gly152 | Lys153 | His154 | His155 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
LGGGGGAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLDEPKKLRPPPARTPCQQ
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Canis familiaris |
113.00 |
1 |
PREDICTED: similar to Insulin-like growth factor b |
| 2 |
Homo sapiens |
111.00 |
5 |
insulin-like growth factor binding protein 2, 36kD |
| 3 |
N/A |
111.00 |
2 |
- |
| 4 |
Sus scrofa |
111.00 |
1 |
insulin-like growth factor binding protein 2 |
| 5 |
synthetic construct |
111.00 |
1 |
insulin-like growth factor binding protein 2, 36kD |
| 6 |
Bubalus bubalis |
111.00 |
1 |
insulin-like growth factor binding protein-2 |
| 7 |
Pan troglodytes |
111.00 |
1 |
PREDICTED: insulin-like growth factor binding prot |
| 8 |
Bos taurus |
111.00 |
1 |
insulin-like growth factor binding protein 2, 36kD |
| 9 |
Macaca mulatta |
109.00 |
1 |
PREDICTED: insulin-like growth factor binding prot |
| 10 |
Ovis aries |
106.00 |
1 |
insulin-like growth factor-binding protein-2 |
| 11 |
Mus musculus |
97.40 |
3 |
unnamed protein product |
| 12 |
Rattus norvegicus |
94.70 |
3 |
insulin-like growth factor binding protein 2 |
| 13 |
Equus caballus |
92.80 |
1 |
insulin-like growth factor binding protein-2 |
| 14 |
Monodelphis domestica |
77.40 |
1 |
PREDICTED: similar to Insulin-like growth factor-b |
| 15 |
Gallus gallus |
72.80 |
3 |
insulin-like growth factor binding protein 2 |
| 16 |
Coturnix coturnix |
60.10 |
1 |
AF260701_1 IGF binding protein 2 |
Top-ranked sequences
| organism | matching |
|---|
| Canis familiaris |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
|
| Homo sapiens |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||||||||||||||||||||||#|||||||||||||+||||||||||||||||
Sbjct 106 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLEEPKKLRPPPARTPCQQ 157
|
| N/A |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||||||||||||||||||||||#|||||||||||||+||||||||||||||||
Sbjct 181 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLEEPKKLRPPPARTPCQQ 232
|
| Sus scrofa |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||||||||||||||||||||||#|||||||||||||+||||||||||||||||
Sbjct 169 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLEEPKKLRPPPARTPCQQ 220
|
| synthetic construct |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||||||||||||||||||||||#|||||||||||||+||||||||||||||||
Sbjct 181 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLEEPKKLRPPPARTPCQQ 232
|
| Bubalus bubalis |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||||||||||||||||||||||#|||||||||||||+||||||||||||||||
Sbjct 44 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLEEPKKLRPPPARTPCQQ 95
|
| Pan troglodytes |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||||||||||||||||||||||#|||||||||||||+||||||||||||||||
Sbjct 299 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLEEPKKLRPPPARTPCQQ 350
|
| Bos taurus |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||||||||||||||||||||||#|||||||||||||+||||||||||||||||
Sbjct 170 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLEEPKKLRPPPARTPCQQ 221
|
| Macaca mulatta |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
|||||||||||||||||| |||#|||||||||||||+||||||||||||||||
Sbjct 179 RKPLKSGMKELAVFREKVAEQH#RQMGKGGKHHLGLEEPKKLRPPPARTPCQQ 230
|
| Ovis aries |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||||| |||||||||||||||#|||||||||||||+||||||||||||||||
Sbjct 170 RKPLKFRMKELAVFREKVTEQH#RQMGKGGKHHLGLEEPKKLRPPPARTPCQQ 221
|
| Mus musculus |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
|||||||||||||||||| |||#|||||| | || |+||||||||||||||||
Sbjct 158 RKPLKSGMKELAVFREKVNEQH#RQMGKGAK-HLSLEEPKKLRPPPARTPCQQ 208
|
| Rattus norvegicus |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||| |||||||||||||| |||#|||||| | || |+||||||||||||||||
Sbjct 158 RKPPKSGMKELAVFREKVNEQH#RQMGKGAK-HLSLEEPKKLRPPPARTPCQQ 208
|
| Equus caballus |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGK-HHLGLDEPKKLRPPPARTPCQQ 175
|||||||||||||+||||+ ||#||||+||| ||+ |+|||||||| |||||||
Sbjct 2 RKPLKSGMKELAVYREKVSGQH#RQMGRGGKHHHVVLEEPKKLRPPSARTPCQQ 54
|
| Monodelphis domestica |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
||| ||||||||| |||| ||#||+|| || ++ ||||||| ||||||
Sbjct 172 RKPHKSGMKELAVIREKVIGQH#RQLGKVNMHHHIHEDTKKLRPPPTRTPCQQ 223
|
| Gallus gallus |
Query 124 RKPLKSGMKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
|||||+||||+|| |||| || #||||| || | ++ || | | ||||||
Sbjct 61 RKPLKTGMKEMAVMREKVNEQQ#RQMGKVGKAHHNHEDSKKSRMPTGRTPCQQ 112
|
| Coturnix coturnix |
Query 131 MKELAVFREKVTEQH#RQMGKGGKHHLGLDEPKKLRPPPARTPCQQ 175
|||+|| |||| || #||||| || | ++ || | | ||||||
Sbjct 1 MKEMAVMREKVNEQQ#RQMGKVGKAHHNHEDSKKSRMPTGRTPCQQ 45
|
