XSB2154 : ankyrin repeat domain 2 (stretch responsive muscle) [Homo sapiens]
[ CaMP Format ]
This entry is computationally expanded from SB0102
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | Ankyrin repeat domain-containing protein 2; Skeletal muscle ankyrin repeat protein; hArpp; ankyrin repeat domain 2 (stretch responsive muscle) |
| Gene Names | ANKRD2; ARPP |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 333 aa
Average Mass: 37.121 kDa
Monoisotopic Mass: 37.098 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| SNN_linker 1. | 15 | 40 | 5.4 | 4.8 |
| --- cleavage 76 --- |
| Ank 1. | 153 | 185 | 32.4 | 1.8e-06 |
| Ank 2. | 186 | 218 | 40.0 | 9.3e-09 |
| Ank 3. | 219 | 251 | 29.9 | 1.1e-05 |
| Ank 4. | 252 | 284 | 32.7 | 1.4e-06 |
3. Sequence Information
Fasta Sequence: XSB2154.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] RVRKTSLDLR76-REIIDVGGIQ
Arg76 
Arg
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Arg67 | Val68 | Arg69 | Lys70 | Thr71 | Ser72 | Leu73 | Asp74 | Leu75 | Arg76 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Arg77 | Glu78 | Ile79 | Ile80 | Asp81 | Val82 | Gly83 | Gly84 | Ile85 | Gln86 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
EDEKHHGAQSAALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAS
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Homo sapiens |
117.00 |
10 |
skeletal muscle ankyrin repeat |
| 2 |
Macaca mulatta |
117.00 |
1 |
PREDICTED: similar to ankyrin repeat domain 2 |
| 3 |
Pan troglodytes |
116.00 |
1 |
PREDICTED: ankyrin repeat domain 2 |
| 4 |
Canis familiaris |
107.00 |
1 |
PREDICTED: similar to ankyrin repeat domain 2 |
| 5 |
Monodelphis domestica |
106.00 |
1 |
PREDICTED: similar to ankyrin-repeat PEST sequence |
| 6 |
Rattus norvegicus |
105.00 |
2 |
PREDICTED: similar to Ankyrin repeat domain protei |
| 7 |
Mus musculus |
103.00 |
2 |
ankyrin-repeat PEST sequence and proline-rich regi |
| 8 |
Xenopus laevis |
70.50 |
2 |
ankyrin repeat domain 2 (stretch responsive muscle |
| 9 |
Gallus gallus |
70.50 |
1 |
PREDICTED: similar to skeletal muscle ankyrin repe |
| 10 |
Xenopus tropicalis |
66.20 |
1 |
hypothetical protein LOC100037897 |
Top-ranked sequences
| organism | matching |
|---|
| Homo sapiens |
Query 47 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAS 106
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 47 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAS 106
|
| Macaca mulatta |
Query 47 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAS 106
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 47 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAS 106
|
| Pan troglodytes |
Query 47 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAS 106
||||||||||||||||||||||||||||||#|||||||||||||+||||||||||||||||
Sbjct 194 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIQLRKKRKQKKRDALAAS 253
|
| Canis familiaris |
Query 47 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAS 106
||||| || | |||||||||||||||||||#||||||||||||||||||||||||+||||+
Sbjct 43 EDEKHQGAPSLALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKREALAAA 102
|
| Monodelphis domestica |
Query 47 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDAL 103
|+|||||||+ |||||||||||||||||||#||||||||||||||||||||||||+||
Sbjct 55 ENEKHHGAQNLALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKREAL 111
|
| Rattus norvegicus |
Query 47 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAS 106
|||| | || |||||||||||||||||||#|||||||||||||||||||||||||||||+
Sbjct 123 EDEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAA 182
|
| Mus musculus |
Query 47 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAS 106
|+|| | || |||||||||||||||||||#|||||||||||||||||||||||||||||+
Sbjct 47 EEEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAA 106
|
| Xenopus laevis |
Query 48 DEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKR 100
|||+ + | +|| +||||||+|||#+|||||||||||||+||||+++|+
Sbjct 43 DEKYQPPVNRNLANLKGDDRVRKTSVDLR#KEIIDVGGIQNLIEIRKKRQERKK 95
|
| Gallus gallus |
Query 47 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALA 104
|+|| | ++ ++ +|||+|||++|+|||#||||||| || ||||||+|++++ + |
Sbjct 62 EEEKRQGPRNRGIEAIKGQDRVRRSSVDLR#REIIDVGSIQRLIELRKQRRKRREERAA 119
|
| Xenopus tropicalis |
Query 59 LQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKR 100
| +|| +||||||+|||#+|||||||||||||+||||+++|+
Sbjct 52 LANLKGDDRVRKTSVDLR#KEIIDVGGIQNLIEIRKKRQERKK 93
|
