XSB2160 : ankyrin repeat domain 2 (stretch responsive muscle) [Rattus norvegicus]
[ CaMP Format ]
This entry is computationally expanded from SB0102
* Basic Information
| Organism | Rattus norvegicus (Norway rat) |
| Protein Names | ankyrin repeat domain 2 (stretch responsive muscle) |
| Gene Names | Ankrd2; ankyrin repeat domain 2 (stretch responsive muscle) |
| Gene Locus | 1q51-q53; chromosome 1 |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 328 aa
Average Mass: 36.655 kDa
Monoisotopic Mass: 36.632 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| --- cleavage 72 --- |
| Ank 1. | 149 | 181 | 32.2 | 2.1e-06 |
| Ank 2. | 182 | 214 | 36.3 | 1.2e-07 |
| Ank 3. | 215 | 247 | 33.7 | 7.4e-07 |
| Ank 4. | 248 | 280 | 32.6 | 1.6e-06 |
3. Sequence Information
Fasta Sequence: XSB2160.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] RVRKTSLDLR72-REIIDVGGIQ
Arg72 
Arg
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Arg63 | Val64 | Arg65 | Lys66 | Thr67 | Ser68 | Leu69 | Asp70 | Leu71 | Arg72 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Arg73 | Glu74 | Ile75 | Ile76 | Asp77 | Val78 | Gly79 | Gly80 | Ile81 | Gln82 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
EDEKRLGVQSPALQKVKGQERVRKTSLDLRREIIDVGGIQNLIELRKKRKQKKRDALAAA
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Rattus norvegicus |
115.00 |
2 |
PREDICTED: similar to Ankyrin repeat domain protei |
| 2 |
Mus musculus |
114.00 |
2 |
ankyrin repeat domain 2 |
| 3 |
Homo sapiens |
105.00 |
10 |
ankyrin repeat domain 2 (stretch responsive muscle |
| 4 |
Macaca mulatta |
105.00 |
1 |
PREDICTED: similar to ankyrin repeat domain 2 |
| 5 |
Pan troglodytes |
104.00 |
1 |
PREDICTED: ankyrin repeat domain 2 |
| 6 |
Canis familiaris |
102.00 |
1 |
PREDICTED: similar to ankyrin repeat domain 2 |
| 7 |
Monodelphis domestica |
96.70 |
1 |
PREDICTED: similar to ankyrin-repeat PEST sequence |
| 8 |
Gallus gallus |
70.90 |
1 |
PREDICTED: similar to skeletal muscle ankyrin repe |
| 9 |
Xenopus laevis |
67.40 |
2 |
ankyrin repeat domain 2 (stretch responsive muscle |
| 10 |
Xenopus tropicalis |
66.20 |
1 |
hypothetical protein LOC100037897 |
Top-ranked sequences
| organism | matching |
|---|
| Rattus norvegicus |
Query 43 EDEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAA 102
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 43 EDEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAA 102
|
| Mus musculus |
Query 43 EDEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAA 102
|+||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Sbjct 43 EEEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAA 102
|
| Homo sapiens |
Query 43 EDEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAA 102
|||| | || |||||||||||||||||||#|||||||||||||||||||||||||||||+
Sbjct 74 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAS 133
|
| Macaca mulatta |
Query 43 EDEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAA 102
|||| | || |||||||||||||||||||#|||||||||||||||||||||||||||||+
Sbjct 246 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAS 305
|
| Pan troglodytes |
Query 43 EDEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAA 102
|||| | || |||||||||||||||||||#|||||||||||||+|||||||||||||||+
Sbjct 194 EDEKHHGAQSAALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIQLRKKRKQKKRDALAAS 253
|
| Canis familiaris |
Query 43 EDEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALAAA 102
|||| | | |||||||||||||||||||#||||||||||||||||||||||||+|||||
Sbjct 43 EDEKHQGAPSLALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKREALAAA 102
|
| Monodelphis domestica |
Query 43 EDEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDAL 99
|+|| | |+ |||||||||||||||||||#||||||||||||||||||||||||+||
Sbjct 55 ENEKHHGAQNLALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKREAL 111
|
| Gallus gallus |
Query 43 EDEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKRDALA 100
|+||| | ++ ++ +|||+|||++|+|||#||||||| || ||||||+|++++ + |
Sbjct 62 EEEKRQGPRNRGIEAIKGQDRVRRSSVDLR#REIIDVGSIQRLIELRKQRRKRREERAA 119
|
| Xenopus laevis |
Query 44 DEKRLGVQSPALQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKR 96
||| + | +|| +||||||+|||#+|||||||||||||+||||+++|+
Sbjct 43 DEKYQPPVNRNLANLKGDDRVRKTSVDLR#KEIIDVGGIQNLIEIRKKRQERKK 95
|
| Xenopus tropicalis |
Query 55 LQKVKGQERVRKTSLDLR#REIIDVGGIQNLIELRKKRKQKKR 96
| +|| +||||||+|||#+|||||||||||||+||||+++|+
Sbjct 52 LANLKGDDRVRKTSVDLR#KEIIDVGGIQNLIEIRKKRQERKK 93
|
* References
[PubMed ID: 15222314] Fujiwara M, Tsukamoto Y, Miyazaki A, Moriyama M, Satoh H, Assignment of the murine ankyrin-repeated protein gene (Ankrd2) to mouse chromosome 19C3-->D1 and rat chromosome 1q51-->q53 by fluorescence in situ hybridization. Cytogenet Genome Res. 2004;105(1):159.
