logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2163 : cortactin [Pongo abelii]

[ CaMP Format ]

This entry is computationally expanded from SB0022

* Basic Information

OrganismPongo abelii (Sumatran orangutan)
Protein NamesPutative uncharacterized protein DKFZp459H142; cortactin
Gene NamesCTTN; DKFZp459H142; cortactin
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001127021 NM_001133549 100174046 Q5R464_PONAB N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 513 aa

Average Mass: 57.411 kDa

Monoisotopic Mass: 57.376 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
HS1_rep 1. 8311968.23.1e-17
HS1_rep 2. 12015672.71.3e-18
HS1_rep 3. 15719374.44.1e-19
HS1_rep 4. 19423069.99.2e-18
HS1_rep 5. 23126771.92.4e-18
HS1_rep 6. 26830429.71.2e-05
--- cleavage 299 (inside HS1_rep 268..304) ---
--- cleavage 309 ---
--- cleavage 321 ---
--- cleavage 314 ---
SH3_1 1. 45851290.18e-24

3. Sequence Information

Fasta Sequence: XSB2163.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

4 [sites]

Cleavage sites (±10aa)

[Site 1] TVPVEAVASK309-TSNIRANFEN

Lys309 Thr

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Thr300Val301Pro302Val303Glu304Ala305Val306Ala307Ser308Lys309
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Thr310Ser311Asn312Ile313Arg314Ala315Asn316Phe317Glu318Asn319

Sequence conservation (by blast)

[Site 2] VTQVSSAYQK299-TVPVEAVASK

Lys299 Thr

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Val290Thr291Gln292Val293Ser294Ser295Ala296Tyr297Gln298Lys299
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Thr300Val301Pro302Val303Glu304Ala305Val306Ala307Ser308Lys309

Sequence conservation (by blast)

[Site 3] NIRANFENLA321-KEKEQEDRRK

Ala321 Lys

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Asn312Ile313Arg314Ala315Asn316Phe317Glu318Asn319Leu320Ala321
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Lys322Glu323Lys324Glu325Gln326Glu327Asp328Arg329Arg330Lys331

Sequence conservation (by blast)

[Site 4] AVASKTSNIR314-ANFENLAKEK

Arg314 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ala305Val306Ala307Ser308Lys309Thr310Ser311Asn312Ile313Arg314
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala315Asn316Phe317Glu318Asn319Leu320Ala321Lys322Glu323Lys324

Sequence conservation (by blast)

* References

None.