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XSB2175 : Protein kinase C, alpha [Bos taurus]

[ CaMP Format ]

This entry is computationally expanded from SB0055

* Basic Information

OrganismBos taurus (cattle)
Protein NamesProtein kinase C, alpha; protein kinase C; alpha
Gene NamesPRKCA
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAI51472 N/A 282001 B0JYP1_BOVIN N/A N/A N/A bta:282001

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 672 aa

Average Mass: 76.793 kDa

Monoisotopic Mass: 76.743 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
C1_1 1. 378983.86e-22
C1_1 2. 10215492.51.5e-24
C2 1. 173260135.61.6e-37
--- cleavage 309 ---
--- cleavage 324 ---
--- cleavage 316 ---
Pkinase 1. 339597288.91.1e-83
Pkinase_C 1. 61766255.81.6e-13

3. Sequence Information

Fasta Sequence: XSB2175.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

3 [sites]

Cleavage sites (±10aa)

[Site 1] ELRQKFEKAK309-LGPAGNKVIS

Lys309 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu300Leu301Arg302Gln303Lys304Phe305Glu306Lys307Ala308Lys309
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu310Gly311Pro312Ala313Gly314Asn315Lys316Val317Ile318Ser319

Sequence conservation (by blast)

[Site 2] NKVISPSEDR324-RQPSNNLDRV

Arg324 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Asn315Lys316Val317Ile318Ser319Pro320Ser321Glu322Asp323Arg324
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Arg325Gln326Pro327Ser328Asn329Asn330Leu331Asp332Arg333Val334

Sequence conservation (by blast)

[Site 3] KAKLGPAGNK316-VISPSEDRRQ

Lys316 Val

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys307Ala308Lys309Leu310Gly311Pro312Ala313Gly314Asn315Lys316
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Val317Ile318Ser319Pro320Ser321Glu322Asp323Arg324Arg325Gln326

Sequence conservation (by blast)

* References

None.