XSB2177 : protein kinase C, alpha [Oryctolagus cuniculus]
[ CaMP Format ]
This entry is computationally expanded from SB0055
* Basic Information
| Organism | Oryctolagus cuniculus (rabbit) |
| Protein Names | Protein kinase C alpha type; PKC-alpha; PKC-A; 2.7.11.13; protein kinase C; alpha |
| Gene Names | PRKCA; protein kinase C, alpha |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| NP_001095194 | NM_001101724 | 100037720 | KPCA_RABIT | N/A | N/A | N/A | N/A |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 672 aa
Average Mass: 76.782 kDa
Monoisotopic Mass: 76.732 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| C1_1 1. | 37 | 89 | 83.2 | 9.4e-22 |
| C1_1 2. | 102 | 154 | 92.5 | 1.5e-24 |
| C2 1. | 173 | 260 | 137.9 | 3.3e-38 |
| --- cleavage 309 --- | ||||
| --- cleavage 324 --- | ||||
| --- cleavage 316 --- | ||||
| Pkinase 1. | 339 | 597 | 290.4 | 4.1e-84 |
| Pkinase_C 1. | 617 | 662 | 53.5 | 7.9e-13 |
3. Sequence Information
Fasta Sequence: XSB2177.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
3 [sites]
Cleavage sites (±10aa)
[Site 1] ELRQKFEKAK309-LGPAGNKVIS
Lys309 
Leu
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Glu300 | Leu301 | Arg302 | Gln303 | Lys304 | Phe305 | Glu306 | Lys307 | Ala308 | Lys309 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Leu310 | Gly311 | Pro312 | Ala313 | Gly314 | Asn315 | Lys316 | Val317 | Ile318 | Ser319 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| QEEGEYYNVPIPEGDEDGNVELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDF |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Oryctolagus cuniculus | 126.00 | 5 | KPCA_RABIT Protein kinase C alpha type (PKC-alpha) |
| 2 | Rattus norvegicus | 124.00 | 5 | PREDICTED: similar to Protein kinase C alpha type |
| 3 | N/A | 123.00 | 13 | - |
| 4 | Homo sapiens | 123.00 | 11 | protein kinase C, alpha |
| 5 | Mus musculus | 123.00 | 9 | protein kinase C |
| 6 | Canis familiaris | 123.00 | 5 | PREDICTED: similar to Protein kinase C, alpha type |
| 7 | Bos taurus | 123.00 | 4 | protein kinase C, alpha |
| 8 | synthetic construct | 123.00 | 1 | protein kinase C alpha |
| 9 | Gallus gallus | 111.00 | 3 | protein kinase C, alpha |
| 10 | Monodelphis domestica | 110.00 | 4 | PREDICTED: similar to protein kinase C |
| 11 | Xenopus tropicalis | 103.00 | 1 | hypothetical protein LOC780209 |
| 12 | Latimeria chalumnae | 101.00 | 2 | protein kinase C alpha |
| 13 | Xenopus laevis | 96.70 | 1 | protein kinase C, alpha |
| 14 | Protopterus dolloi | 90.50 | 2 | protein kinase C alpha |
| 15 | Takifugu rubripes | 80.10 | 1 | protein kinase C, alpha type |
| 16 | Scyliorhinus canicula | 72.00 | 2 | protein kinase C alpha |
| 17 | Danio rerio | 68.60 | 7 | protein kinase C, beta 1 |
| 18 | Tetraodon nigroviridis | 66.60 | 3 | unnamed protein product |
| 19 | Petromyzon marinus | 60.80 | 1 | protein kinase C |
| 20 | Macaca mulatta | 59.70 | 10 | PREDICTED: protein kinase C, beta 1 isoform 5 |
| 21 | Myxine glutinosa | 53.10 | 1 | protein kinase C |
| 22 | Macaca fascicularis | 42.70 | 1 | KPCG_MACFA Protein kinase C gamma type (PKC-gamma) |
| 23 | Anopheles gambiae str. PEST | 39.70 | 1 | ENSANGP00000009078 |
| 24 | Branchiostoma lanceolatum | 39.70 | 1 | protein kinase C |
| 25 | Bombyx mori | 38.50 | 1 | conventional protein kinase C |
| 26 | Apis mellifera | 38.10 | 1 | PREDICTED: similar to Protein C kinase 53E CG6622- |
| 27 | Aedes aegypti | 37.00 | 1 | protein kinase c |
| 28 | Drosophila melanogaster | 36.60 | 4 | Protein C kinase 53E CG6622-PA, isoform A |
| 29 | Aplysia californica | 34.30 | 1 | KPC1_APLCA Calcium-dependent protein kinase C (APL |
| 30 | Drosophila pseudoobscura | 32.70 | 1 | GA19732-PA |
Top-ranked sequences
| organism | matching |
|---|---|
| Oryctolagus cuniculus | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| Rattus norvegicus | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||+|||||||||||||#|||||||||||||||||||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| N/A | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||+||+||||||||||#|||||||||||||||||||||||||||||| Sbjct 266 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 325 |
| Homo sapiens | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||+||+||||||||||#|||||||||||||||||||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| Mus musculus | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||+||+||||||||||#|||||||||||||||||||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| Canis familiaris | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||+|||||||||||||#|||||||||||||||+|||||||||||||| Sbjct 198 QEEGEYYNVPIPEGDEEGNVELRQKFEKAK#LGPAGNKVISPSEDRRQPSNNLDRVKLTDF 257 |
| Bos taurus | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||+|||||||||||||#|||||||||||||||+|||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNVELRQKFEKAK#LGPAGNKVISPSEDRRQPSNNLDRVKLTDF 339 |
| synthetic construct | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||+||+||||||||||#|||||||||||||||||||||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |
| Gallus gallus | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQ--PSNNLDRVKLT 337 ||||||||||||+ ||||| ||||||||||#|||||||||+||||| ||||||||||| Sbjct 280 QEEGEYYNVPIPDADEDGNAELRQKFEKAK#LGPAGNKVITPSEDRNSSVPSNNLDRVKLT 339 Query 338 DF 339 || Query 338 DF 339 |
| Monodelphis domestica | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||||||+||+||||||||||#||| |||||| |+||| |+||||||||||| Sbjct 280 QEEGEYYNVPIPEGDEEGNMELRQKFEKAK#LGPVGNKVISSSDDRK-PTNNLDRVKLTDF 338 |
| Xenopus tropicalis | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQ--PSNNLDRVKLT 337 ||||||||||||| ++|||+||||||||||#|||||||||||+++|+ ||||+| |+|| Sbjct 284 QEEGEYYNVPIPEEEDDGNIELRQKFEKAK#LGPAGNKVISPTDERRPYVPSNNIDSVRLT 343 Query 338 DF 339 || Query 338 DF 339 |
| Latimeria chalumnae | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQ--PSNNLDRVKLT 337 ||||||||||| | | ||||||||||||||#|||||+||||| |+|| ||||||||||| Sbjct 202 QEEGEYYNVPISEAD-DGNVELRQKFEKAK#LGPAGSKVISPVEERKSSTPSNNLDRVKLT 260 Query 338 DF 339 || Query 338 DF 339 |
| Xenopus laevis | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQ--PSNNLDRVKLT 337 ||||||||||||| | |||+||||||||||#|||||||||+|+ +|+ ||||+| ++|| Sbjct 284 QEEGEYYNVPIPEAD-DGNLELRQKFEKAK#LGPAGNKVINPTGERRPYIPSNNIDSIRLT 342 Query 338 DF 339 || Query 338 DF 339 |
| Protopterus dolloi | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||||+ | |||| ||||||||+#||||| ||||| | ||||| || || Sbjct 200 QEEGEYYNVPIPDAD-DGNVGLRQKFEKAR#LGPAGKKVISPERKSSLPLNNLDRFKLEDF 258 |
| Takifugu rubripes | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRK--QPSNNLDRVKLT 337 ||||||||||||| | | |+||||||||||#|| | |||+||+ |+ || |+|||+| Sbjct 278 QEEGEYYNVPIPEVD-DVNLELRQKFEKAK#LG-QGKKVITPSDHRRFSLPSGNMDRVRLN 335 Query 338 DF 339 || Query 338 DF 339 |
| Scyliorhinus canicula | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 ||||||||||| | ||| |||+||||||#||||| | | + |+|+|| | | || Sbjct 213 QEEGEYYNVPIIEDDEDS--ELRKKFEKAK#LGPAGKKAI--EKKPSSPTNDLDHVHLEDF 268 |
| Danio rerio | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSN-NLDRVKLTD 338 ||||||+|||+| |+|| |||||||+||#+||+ | + | || | ||+||+| Sbjct 279 QEEGEYFNVPVPPEGEEGNEELRQKFERAK#IGPSKTDGSSSNAISKFDSNGNRDRMKLSD 338 Query 339 F 339 | Query 339 F 339 |
| Tetraodon nigroviridis | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNK--VISPSEDRKQPSNNLDRVKLT 337 ||||||+|||+| |+|| |||||||+||#+|| | + + | + | ||+|| Sbjct 216 QEEGEYFNVPVPPEGEEGNEELRQKFERAK#IGPGKNTDGKSANAASRFDSNGNQDRMKLA 275 Query 338 DF 339 || Query 338 DF 339 |
| Petromyzon marinus | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISP--SEDRKQPS-------NN 330 ||||||||||| |||+ |+|+|||||+#|||+ + | |++|+ | | Sbjct 210 QEEGEYYNVPIAPDIEDGDTEMRRKFEKAR#LGPS----VKPRASDERRANSLSAILNNAN 265 Query 331 LDRVKLTDF 339 +|||| || Sbjct 266 VDRVKADDF 274 |
| Macaca mulatta | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKV----ISPSEDRKQPSNNLDRVK 335 ||||||+|||+| +|| |||||||+||#+ | || + + + + | ||+| Sbjct 280 QEEGEYFNVPVPPEGSEGNEELRQKFERAK#IS-QGTKVPEEKTTNTVSKFDNNGNRDRMK 338 Query 336 LTDF 339 |||| Query 336 LTDF 339 |
| Myxine glutinosa | Query 280 QEEGEYYNVPI-PEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPS---NNLDRVK 335 ||||||||||+ |||+| +||||+ ++++#+ + ||++|+ | + |||| Sbjct 201 QEEGEYYNVPVAPEGEE--GLELRQRLQRSQ#IARSDKNKQSPAKDQPSDSASLSGLDRVN 258 Query 336 LTDF 339 | || Sbjct 259 LEDF 262 |
| Macaca fascicularis | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKF----------EKAK#LGPAGNKVISPSEDRKQPSN 329 ||||||||||+ + | | | ||| |+ +#+||+ + + ||| | Sbjct 280 QEEGEYYNVPVADAD---NCSLLQKFEACNYPLELYERVR#MGPSSSPIPSPSPSPTDPKR 336 Query 330 -----NLDRVKLTDF 339 + |+ ++|| Sbjct 337 CFFGASPGRLHISDF 351 |
| Anopheles gambiae str. PEST | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSN--NLDRVKLT 337 ||||||||||+|| | |+|+ + | #+ | | |+ | | | ++ | Sbjct 220 QEEGEYYNVPVPEEGAD-LVQLKSQMRKTS#I----TKKIPMMGDKDVPHNMTKKDVIRAT 274 Query 338 DF 339 || Query 338 DF 339 |
| Branchiostoma lanceolatum | Query 280 QEEGEYYNVPIPEGDEDGNV-ELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTD 338 ||||||||||| ||+ || +|++ +| |#| + ||+ +|| +| | Sbjct 211 QEEGEYYNVPI--ADEEENVAKLKEHLQKQK#LDEQRKQKSKRSEECN--IGSLDHMKAAD 266 Query 339 F 339 | Query 339 F 339 |
| Bombyx mori | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSN--NLDRVKLT 337 |||||+||||+|| | | | + +# | + | ||+ | | | ++ | Sbjct 283 QEEGEFYNVPVPEEGAD----LVQLKNQMR#ATTVGARRPPPPPDREVPHNVAAADVIRAT 338 Query 338 DF 339 || Query 338 DF 339 |
| Apis mellifera | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSN--NLDRVKLT 337 ||||||||||+|| | ||+ | |# + | + ++|++ | | | ++ + Sbjct 297 QEEGEYYNVPVPEEGVD-LAELKMKPSPQK#--TSVTKKTTTTQDKEVPHNMGKSDLIRAS 353 Query 338 DF 339 || Query 338 DF 339 |
| Aedes aegypti | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSN--NLDRVKLT 337 ||||||||||+|| | |+|+ + | #+ +| |+ | | | ++ | Sbjct 228 QEEGEYYNVPVPEEGTD-LVQLKSQMRKTS#I----SKKAPVLCDKDVPHNMGKKDVIRAT 282 Query 338 DF 339 || Query 338 DF 339 |
| Drosophila melanogaster | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |+|||||||| + || ++|+|| + |# ++ |+ |+ | ++ ||| Sbjct 289 QDEGEYYNVPCAD-DEQDLLKLKQKPSQKK#------PMVMRSDTNTHTSSKKDMIRATDF 341 |
| Aplysia californica | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPSNNLDRVKLTDF 339 |||||+| ||+ + + |++ | ++ #+ ++ | |+ | + | |+ +|| Sbjct 264 QEEGEFYGVPVTDDITESIQEIKSKMHRSS#I---SSEKRYPEPDKVQNMSKQDIVRASDF 320 |
| Drosophila pseudoobscura | Query 280 QEEGEYYNVPIPEGDEDGNVELRQKFEKAK#LGPAGNKVISPSEDRKQPS--NNLDRVKLT 337 |+|||||||| + || ++|+|| # |+ | + | | + | ++ | Sbjct 175 QDEGEYYNVPCAD-DEQDLLKLKQK-----#--PSQKKPLVMRSDTNTHSSISKKDMIRAT 226 Query 338 DF 339 || Query 338 DF 339 |
[Site 2] NKVISPSEDR324-KQPSNNLDRV
Arg324 Lys
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Asn315 | Lys316 | Val317 | Ile318 | Ser319 | Pro320 | Ser321 | Glu322 | Asp323 | Arg324 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Lys325 | Gln326 | Pro327 | Ser328 | Asn329 | Asn330 | Leu331 | Asp332 | Arg333 | Val334 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| EDGNVELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVM |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Oryctolagus cuniculus | 122.00 | 6 | KPCA_RABIT Protein kinase C alpha type (PKC-alpha) |
| 2 | Rattus norvegicus | 121.00 | 8 | PREDICTED: similar to Protein kinase C alpha type |
| 3 | Homo sapiens | 120.00 | 24 | protein kinase C, alpha |
| 4 | N/A | 120.00 | 16 | - |
| 5 | Canis familiaris | 120.00 | 13 | PREDICTED: similar to Protein kinase C, alpha type |
| 6 | Mus musculus | 120.00 | 11 | protein kinase C |
| 7 | Bos taurus | 120.00 | 7 | protein kinase C, alpha |
| 8 | synthetic construct | 120.00 | 4 | protein kinase C alpha |
| 9 | Gallus gallus | 111.00 | 7 | protein kinase C, alpha |
| 10 | Latimeria chalumnae | 108.00 | 2 | protein kinase C alpha |
| 11 | Monodelphis domestica | 106.00 | 6 | PREDICTED: similar to protein kinase C |
| 12 | Xenopus tropicalis | 102.00 | 3 | hypothetical protein LOC780209 |
| 13 | Xenopus laevis | 97.40 | 2 | protein kinase C, alpha |
| 14 | Protopterus dolloi | 94.70 | 2 | protein kinase C alpha |
| 15 | Takifugu rubripes | 82.00 | 1 | protein kinase C, alpha type |
| 16 | Scyliorhinus canicula | 77.80 | 2 | protein kinase C alpha |
| 17 | Danio rerio | 75.10 | 14 | protein kinase C, beta 1 |
| 18 | Tetraodon nigroviridis | 73.20 | 5 | unnamed protein product |
| 19 | Petromyzon marinus | 68.90 | 1 | protein kinase C |
| 20 | Macaca mulatta | 66.20 | 15 | PREDICTED: protein kinase C, beta 1 isoform 5 |
| 21 | Myxine glutinosa | 53.90 | 1 | protein kinase C |
| 22 | Macaca fascicularis | 50.10 | 4 | KPCG_MACFA Protein kinase C gamma type (PKC-gamma) |
| 23 | Branchiostoma lanceolatum | 48.50 | 1 | protein kinase C |
| 24 | Aplysia californica | 47.00 | 2 | KPC2_APLCA Calcium-independent protein kinase C (A |
| 25 | Bombyx mori | 47.00 | 1 | conventional protein kinase C |
| 26 | Anopheles gambiae str. PEST | 46.20 | 3 | ENSANGP00000009078 |
| 27 | Apis mellifera | 45.40 | 2 | PREDICTED: similar to Protein C kinase 53E CG6622- |
| 28 | Drosophila melanogaster | 44.30 | 8 | Protein C kinase 53E CG6622-PA, isoform A |
| 29 | Aedes aegypti | 44.30 | 2 | protein kinase c |
| 30 | Tribolium castaneum | 42.00 | 3 | PREDICTED: similar to CG6622-PA, isoform A |
| 31 | Drosophila pseudoobscura | 41.20 | 3 | GA19732-PA |
| 32 | Magnaporthe grisea 70-15 | 41.20 | 1 | hypothetical protein MGG_08689 |
| 33 | Coprinopsis cinerea okayama7#130 | 41.20 | 1 | hypothetical protein CC1G_07190 |
| 34 | Caenorhabditis briggsae | 41.20 | 1 | Hypothetical protein CBG16150 |
| 35 | Magnaporthe grisea | 40.80 | 1 | AF136600_1 protein kinase C |
| 36 | Caenorhabditis elegans | 40.40 | 5 | protein kinase C2 A isoform |
| 37 | Strongylocentrotus purpuratus | 40.40 | 4 | PREDICTED: similar to protein kinase C |
| 38 | Botryotinia fuckeliana | 39.70 | 1 | protein kinase C |
| 39 | Schizosaccharomyces pombe | 39.30 | 3 | SPAC17G8.14c |
| 40 | Schizosaccharomyces pombe 972h- | 39.30 | 2 | hypothetical protein SPAC17G8.14c |
| 41 | Hydractinia echinata | 39.30 | 1 | putative calcium dependent protein kinase C |
| 42 | Yarrowia lipolytica | 38.90 | 1 | hypothetical protein |
| 43 | Tuber excavatum | 38.50 | 2 | protein kinase C-like protein |
| 44 | Asparagus officinalis | 38.50 | 1 | S6 ribosomal protein kinase |
| 45 | Calliphora vicina | 38.50 | 1 | eye-specific protein kinase C |
| 46 | Pan troglodytes | 38.10 | 4 | PREDICTED: serum/glucocorticoid regulated kinase 3 |
| 47 | Tuber aestivum | 38.10 | 2 | protein kinase C-like protein |
| 48 | Suberites domuncula | 38.10 | 2 | Serine/Threonine protein kinase |
| 49 | Sycon raphanus | 38.10 | 1 | Serine/Threonine protein kinase |
| 50 | Leishmania braziliensis | 38.10 | 1 | zinc finger protein kinase-like |
| 51 | Leptosphaeria maculans | 38.10 | 1 | AF487263_9 protein kinase C |
| 52 | Cryptococcus neoformans var. neoformans JEC21 | 37.70 | 1 | protein kinase C |
| 53 | Squalus acanthias | 37.70 | 1 | s-sgk1 |
| 54 | Paramecium tetraurelia | 37.70 | 1 | hypothetical protein |
| 55 | Cryptococcus neoformans var. neoformans B-3501A | 37.70 | 1 | hypothetical protein CNBC3910 |
| 56 | Cryptococcus neoformans var. neoformans | 37.70 | 1 | protein kinase C 1 |
| 57 | Cryptococcus neoformans var. grubii | 37.70 | 1 | protein kinase C 1 |
| 58 | Tuber indicum | 37.00 | 6 | protein kinase C-like protein |
| 59 | Phaeosphaeria nodorum SN15 | 37.00 | 2 | hypothetical protein SNOG_13609 |
| 60 | Tuber pseudoexcavatum | 37.00 | 2 | protein kinase C-like protein |
| 61 | Debaryomyces hansenii CBS767 | 36.60 | 1 | hypothetical protein DEHA0G14773g |
| 62 | Aspergillus oryzae | 36.60 | 1 | unnamed protein product |
| 63 | Sporothrix schenckii | 36.60 | 1 | AF124792_1 protein kinase C; serine/threonine prot |
| 64 | Cochliobolus heterostrophus | 36.60 | 1 | KPC1_COCHE Protein kinase C-like emb |
| 65 | Aspergillus clavatus NRRL 1 | 36.60 | 1 | protein kinase c |
| 66 | Hydra vulgaris | 36.20 | 2 | protein kinase C |
| 67 | Plasmodium yoelii yoelii str. 17XNL | 36.20 | 1 | hypothetical protein PY00403 |
| 68 | Medicago truncatula | 36.20 | 1 | Protein kinase |
| 69 | Neosartorya fischeri NRRL 181 | 36.20 | 1 | protein kinase c |
| 70 | Aspergillus terreus NIH2624 | 36.20 | 1 | hypothetical protein ATEG_02078 |
| 71 | Coccidioides immitis RS | 36.20 | 1 | hypothetical protein CIMG_09206 |
| 72 | Plasmodium berghei strain ANKA | 36.20 | 1 | rac-beta serine/threonine protein kinase |
| 73 | Blumeria graminis | 35.80 | 1 | AF247001_1 protein kinase C |
| 74 | Fundulus heteroclitus | 35.80 | 1 | serum and glucocorticoid-regulated kinase |
| 75 | Neurospora crassa | 35.80 | 1 | protein kinase C homologue |
| 76 | Tuber borchii | 35.80 | 1 | protein kinase C homologue |
| 77 | Ashbya gossypii ATCC 10895 | 35.80 | 1 | ACR191Cp |
Top-ranked sequences
| organism | matching |
|---|---|
| Oryctolagus cuniculus | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Rattus norvegicus | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 295 EEGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Homo sapiens | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+||+|||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 295 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| N/A | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+||+|||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 281 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 340 |
| Canis familiaris | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+||||||||||||||||||||||||||||#+||||||||||||||||||||||||||||| Sbjct 213 EEGNVELRQKFEKAKLGPAGNKVISPSEDR#RQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 272 |
| Mus musculus | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+||+|||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 295 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Bos taurus | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+||||||||||||||||||||||||||||#+||||||||||||||||||||||||||||| Sbjct 295 EEGNVELRQKFEKAKLGPAGNKVISPSEDR#RQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| synthetic construct | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+||+|||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 295 EEGNMELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |
| Gallus gallus | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 352 |||| |||||||||||||||||||+|||||# |||||||||||||||||||||||||| Sbjct 295 EDGNAELRQKFEKAKLGPAGNKVITPSEDR#NSSVPSNNLDRVKLTDFNFLMVLGKGSFGK 354 Query 353 VM 354 || Query 353 VM 354 |
| Latimeria chalumnae | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 352 +|||||||||||||||||||+||||| |+|#| |||||||||||||||||||||||||| Sbjct 216 DDGNVELRQKFEKAKLGPAGSKVISPVEER#KSSTPSNNLDRVKLTDFNFLMVLGKGSFGK 275 Query 353 VM 354 || Query 353 VM 354 |
| Monodelphis domestica | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+||+||||||||||||| |||||| |+||#| |+|||||||||||||||||||||||||| Sbjct 295 EEGNMELRQKFEKAKLGPVGNKVISSSDDR#K-PTNNLDRVKLTDFNFLMVLGKGSFGKVM 353 |
| Xenopus tropicalis | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 352 +|||+|||||||||||||||||||||+++|#+ ||||+| |+||||+|||||||||||| Sbjct 299 DDGNIELRQKFEKAKLGPAGNKVISPTDER#RPYVPSNNIDSVRLTDFSFLMVLGKGSFGK 358 Query 353 VM 354 || Query 353 VM 354 |
| Xenopus laevis | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQ--PSNNLDRVKLTDFNFLMVLGKGSFGK 352 +|||+|||||||||||||||||||+|+ +|#+ ||||+| ++|||| |||||||||||| Sbjct 298 DDGNLELRQKFEKAKLGPAGNKVINPTGER#RPYIPSNNIDSIRLTDFCFLMVLGKGSFGK 357 Query 353 VM 354 || Query 353 VM 354 |
| Protopterus dolloi | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 +|||| ||||||||+||||| ||||| # | ||||| || ||||+|||||||||||| Sbjct 214 DDGNVGLRQKFEKARLGPAGKKVISPERKS#SLPLNNLDRFKLEDFNFVMVLGKGSFGKVM 273 |
| Takifugu rubripes | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#K--QPSNNLDRVKLTDFNFLMVLGKGSFGK 352 +| |+|||||||||||| | |||+||+ |#+ || |+|||+| ||||| +|||||||| Sbjct 292 DDVNLELRQKFEKAKLGQ-GKKVITPSDHR#RFSLPSGNMDRVRLNDFNFLALLGKGSFGK 350 Query 353 VM 354 || Query 353 VM 354 |
| Scyliorhinus canicula | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 +| + |||+||||||||||| | | # |+|+|| | | ||||||||||||||||| Sbjct 226 DDEDSELRKKFEKAKLGPAGKKAIEKKPS-#-SPTNDLDHVHLEDFNFLMVLGKGSFGKVM 283 |
| Danio rerio | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSN-NLDRVKLTDFNFLMVLGKGSFGKV 353 |+|| |||||||+||+||+ | + #| || | ||+||+|||||||||||||||| Sbjct 294 EEGNEELRQKFERAKIGPSKTDGSSSNAIS#KFDSNGNRDRMKLSDFNFLMVLGKGSFGKV 353 Query 354 M 354 | Query 354 M 354 |
| Tetraodon nigroviridis | Query 295 EDGNVELRQKFEKAKLGPAGNK--VISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGK 352 |+|| |||||||+||+|| | + + |# + | ||+|| ||||||||||||||| Sbjct 231 EEGNEELRQKFERAKIGPGKNTDGKSANAASR#FDSNGNQDRMKLADFNFLMVLGKGSFGK 290 Query 353 VM 354 || Query 353 VM 354 |
| Petromyzon marinus | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSN---------NLDRVKLTDFNFLMVL 345 |||+ |+|+|||||+|||+ + | #++ +| |+|||| |||||||| Sbjct 225 EDGDTEMRRKFEKARLGPS----VKPRASD#ERRANSLSAILNNANVDRVKADDFNFLMVL 280 Query 346 GKGSFGKVM 354 ||||||||| Query 346 GKGSFGKVM 354 |
| Macaca mulatta | Query 296 DGNVELRQKFEKAKLGPAGNKVISPSE------DR#KQPSNNLDRVKLTDFNFLMVLGKGS 349 +|| |||||||+||+ | || | | +# + | ||+||||||||||||||| Sbjct 296 EGNEELRQKFERAKISQ-GTKV--PEEKTTNTVSK#FDNNGNRDRMKLTDFNFLMVLGKGS 352 Query 350 FGKVM 354 ||||| Query 350 FGKVM 354 |
| Myxine glutinosa | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPS---NNLDRVKLTDFNFLMVLGKGSFG 351 |+| +||||+ +++++ + ||++|+# | + |||| | || || |||||||| Sbjct 216 EEG-LELRQRLQRSQIARSDKNKQSPAKDQ#PSDSASLSGLDRVNLEDFVFLTVLGKGSFG 274 Query 352 KVM 354 ||| Query 352 KVM 354 |
| Macaca fascicularis | Query 305 FEKAKLGPAGNKVISPSEDR#KQPSN-----NLDRVKLTDFNFLMVLGKGSFGKVM 354 +|+ ++||+ + + ||| # | + |+ ++||+|||||||||||||| Sbjct 312 YERVRMGPSSSPIPSPSPSP#TDPKRCFFGASPGRLHISDFSFLMVLGKGSFGKVM 366 |
| Branchiostoma lanceolatum | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ +|++ +| || + ||+ # | || +| ||||||||||||||||| Sbjct 225 EENVAKLKEHLQKQKLDEQRKQKSKRSEEC#NIGS--LDHMKAADFNFLMVLGKGSFGKVM 282 |
| Aplysia californica | Query 314 GNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |++ ||| ||# + ++ |+ | ||||+ ||||||||||| Sbjct 380 GSRTRSPSSDR#SRSHHS--RISLHDFNFIKVLGKGSFGKVM 418 |
| Bombyx mori | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSFGK 352 |+| +| | + + | + | ||#+ | | | ++ |||||+|||||||||| Sbjct 295 EEG-ADLVQLKNQMRATTVGARRPPPPPDR#EVPHNVAAADVIRATDFNFIMVLGKGSFGK 353 Query 353 VM 354 || Query 353 VM 354 |
| Anopheles gambiae str. PEST | Query 299 VELRQKFEKAKLGPAGNKVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSFGKVM 354 |+|+ + | + | | |+# | | | ++ |||||||||||||||||| Sbjct 238 VQLKSQMRKTSI----TKKIPMMGDK#DVPHNMTKKDVIRATDFNFLMVLGKGSFGKVM 291 |
| Apis mellifera | Query 316 KVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSFGKVM 354 | + ++|+#+ | | | ++ +||||||||||||||||| Sbjct 330 KKTTTTQDK#EVPHNMGKSDLIRASDFNFLMVLGKGSFGKVM 370 |
| Drosophila melanogaster | Query 303 QKFEKAKLGPAGNK-VISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | | | |+ | ++ |+ # |+ | ++ |||||+ ||||||||||+ Sbjct 304 QDLLKLKQKPSQKKPMVMRSDTN#THTSSKKDMIRATDFNFIKVLGKGSFGKVL 356 |
| Aedes aegypti | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+| ++ | + | + + +| # | ++ |||||||||||||||||| Sbjct 240 EEGTDLVQLKSQMRKTSISKKAPVLCDKDV#PHNMGKKDVIRATDFNFLMVLGKGSFGKVM 299 |
| Tribolium castaneum | Query 324 R#KQPSNN--LDRVKLTDFNFLMVLGKGSFGKVM 354 +#++|| + | ++ +||||||||||||||||| Sbjct 320 Q#RRPSQHGQKDIIRASDFNFLMVLGKGSFGKVM 352 |
| Drosophila pseudoobscura | Query 303 QKFEKAKLGPAGNKVISPSEDR#KQPSN--NLDRVKLTDFNFLMVLGKGSFGKVM 354 | | | |+ | + | # |+ | ++ |||||+ ||||||||||+ Sbjct 190 QDLLKLKQKPSQKKPLVMRSDT#NTHSSISKKDMIRATDFNFIKVLGKGSFGKVL 243 |
| Magnaporthe grisea 70-15 | Query 302 RQKFEKAKLGPAGNKVISPSEDR#KQPS----NNLDRVKLTDFNFLMVLGKGSFGKVM 354 +| |+ + | || | |# || |+ | |||| |||||+||||| Sbjct 816 QQHQEQQIISPTAGTVIPTSAKR#PLPSATDPGTGQRIGLDHFNFLAVLGKGNFGKVM 872 |
| Coprinopsis cinerea okayama7#130 | Query 306 EKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ++ + | + + ++ +#+||| +| | ||||| |||||+||||| Sbjct 685 QQGMVPPQHQQQMIQAQPQ#RQPSKKR-KVGLDDFNFLAVLGKGNFGKVM 732 |
| Caenorhabditis briggsae | Query 328 SNNLDRVKLTDFNFLMVLGKGSFGKVM 354 + | | +| +||||| ||||||||||+ Sbjct 404 NTNRDVIKASDFNFLTVLGKGSFGKVL 430 |
| Magnaporthe grisea | Query 302 RQKFEKAKLGPAGNKVISPSEDR#KQPS----NNLDRVKLTDFNFLMVLGKGSFGKVM 354 +| |+ + | || | |# || |+ | |||| |||||+||||| Sbjct 816 QQHQEQQIISPTAGTVIPTSARR#PLPSATDPGTGQRIGLDHFNFLAVLGKGNFGKVM 872 |
| Caenorhabditis elegans | Query 328 SNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+| + +| +||||| ||||||||||+ Sbjct 337 SSNHNVIKASDFNFLTVLGKGSFGKVL 363 |
| Strongylocentrotus purpuratus | Query 321 SEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | # ++++ |+ +||||| ||||||||||| Sbjct 307 SSQN#SNSNSSMGLVRASDFNFLSVLGKGSFGKVM 340 |
| Botryotinia fuckeliana | Query 312 PAGNKVISPSEDR#KQPSNNLD-----RVKLTDFNFLMVLGKGSFGKVM 354 | +|+ + |#|| | |+ | |||| |||||+||||| Sbjct 813 PGSQQVVPQGQQR#KQVPAANDAGTGRRIGLDHFNFLAVLGKGNFGKVM 860 |
| Schizosaccharomyces pombe | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | |#++ | || | || || |||||+||||| Sbjct 556 PESPR#REKKN---RVTLDDFTFLAVLGKGNFGKVM 587 |
| Schizosaccharomyces pombe 972h- | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | |#++ | || | || || |||||+||||| Sbjct 648 PESPR#REKKN---RVTLDDFTFLAVLGKGNFGKVM 679 |
| Hydractinia echinata | Query 332 DRVKLTDFNFLMVLGKGSFGKVM 354 +|+|| || || |+||||||||| Sbjct 191 ERLKLEDFTFLKVIGKGSFGKVM 213 |
| Yarrowia lipolytica | Query 308 AKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | || |+ | +#|+| |+ | ||||| |||||+||||| Sbjct 900 ASPAPASNRH-SVVGKK#KRP-----RIGLDDFNFLAVLGKGNFGKVM 940 |
| Tuber excavatum | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ + #+|| ++ | |||| |||||+||||| Sbjct 312 PAPEP#QQPVIRPAKIGLDHFNFLAVLGKGNFGKVM 346 |
| Asparagus officinalis | Query 321 SEDR#KQPSN-NLDRVKLTDFNFLMVLGKGSFGKV 353 +|+ #+ ||+ |++|| | ||+|| |+|+|+|||| Sbjct 106 AEEH#EVPSSENVERVGLEDFDFLKVVGQGAFGKV 139 |
| Calliphora vicina | Query 320 PSEDR#KQPSNNL---DRVKLTDFNFLMVLGKGSFGKVM 354 | | #| +|+ | ++ ||||+ ||||||+||++ Sbjct 333 PRIDN#KDMPHNMSKRDMIRAADFNFIKVLGKGSYGKIL 370 |
| Pan troglodytes | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | + +| + |||+|| | # |||+|| |+||||||||+ Sbjct 134 ERSSQKLHSTSQNINLGPSGNPHAKP----#------------TDFDFLKVIGKGSFGKVL 177 |
| Tuber aestivum | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ + #+ | + ++ | |||| |||||+||||| Sbjct 314 PAPEP#QPPVSRPTKIGLDHFNFLAVLGKGNFGKVM 348 |
| Suberites domuncula | Query 328 SNNLDRVKLTDFNFLMVLGKGSFGKV 353 + ++ ++|| ||| |+|||||||||| Sbjct 332 AKDMPKMKLEDFNLLVVLGKGSFGKV 357 |
| Sycon raphanus | Query 335 KLTDFNFLMVLGKGSFGKVM 354 ||+||+|| ||||||||||| Sbjct 362 KLSDFSFLKVLGKGSFGKVM 381 |
| Leishmania braziliensis | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | | | +|+ + + ++|| # |+|| | | || | |+|+|+||||+ Sbjct 591 ESGQVMQQQRVINSTSPIPYSSLLSPRGSL#VSRSDNLSPVGLQDFQLLTVIGRGTFGKVL 650 |
| Leptosphaeria maculans | Query 308 AKLGPAGNKVISPSEDR#KQPSNNLD----RVKLTDFNFLMVLGKGSFGKVM 354 |++ |+ + |++# || | |+ | |||| |||||+||||| Sbjct 825 AQIPPSKQLPPANPENK#VTPSANTQGSGKRIGLDHFNFLAVLGKGNFGKVM 875 |
| Cryptococcus neoformans var. neoformans JEC21 | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 +| | ||||| |||||+||||| Sbjct 751 KVGLDDFNFLAVLGKGNFGKVM 772 |
| Squalus acanthias | Query 327 PSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ||+| + | +||||| |+||||||||+ Sbjct 89 PSSN-PQAKPSDFNFLKVIGKGSFGKVL 115 |
| Paramecium tetraurelia | Query 295 EDGNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ++| ++ +| || ++ | # | |||||| | |||+||||||| Sbjct 32 KEGEQQMNDEFMKAPTATF-EQIEETGEQV#FVDDNREAIVKLTDFQFEKVLGRGSFGKVM 90 |
| Cryptococcus neoformans var. neoformans B-3501A | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 +| | ||||| |||||+||||| Sbjct 754 KVGLDDFNFLAVLGKGNFGKVM 775 |
| Cryptococcus neoformans var. neoformans | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 +| | ||||| |||||+||||| Sbjct 751 KVGLDDFNFLAVLGKGNFGKVM 772 |
| Cryptococcus neoformans var. grubii | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 +| | ||||| |||||+||||| Sbjct 751 KVGLDDFNFLAVLGKGNFGKVM 772 |
| Tuber indicum | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ + #+| + ++ | |||| |||||+||||| Sbjct 313 PAPEP#QQVVSKPTKIGLDHFNFLAVLGKGNFGKVM 347 |
| Phaeosphaeria nodorum SN15 | Query 329 NNLDRVKLTDFNFLMVLGKGSFGKVM 354 | ||+ + || | |+||||||||| Sbjct 273 NRQDRLSIDDFELLKVVGKGSFGKVM 298 |
| Tuber pseudoexcavatum | Query 320 PSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ + #+| + ++ | |||| |||||+||||| Sbjct 312 PAPEP#QQVVSKPTKIGLDHFNFLAVLGKGNFGKVM 346 |
| Debaryomyces hansenii CBS767 | Query 326 QPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 +| ++ | || || |||||+||||| Sbjct 750 KPKRRRRKIGLDDFQFLAVLGKGNFGKVM 778 |
| Aspergillus oryzae | Query 312 PAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | + ++ || # | |+ | |||| |||||+||||| Sbjct 741 PVMQQQVAMKEDA#P-PQQPKVRIGLDHFNFLAVLGKGNFGKVM 782 |
| Sporothrix schenckii | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 |+ | +|||| |||||+||||| Sbjct 863 RIGLDNFNFLAVLGKGNFGKVM 884 |
| Cochliobolus heterostrophus | Query 310 LGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 +| | ++|+ + #+ |+ | |||| |||||+||||| Sbjct 823 VGEVPGKKVTPAANT#QGTGK---RIGLDHFNFLAVLGKGNFGKVM 864 |
| Aspergillus clavatus NRRL 1 | Query 312 PAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | +| | #+|| |+ | |||| |||||+||||| Sbjct 763 PMQQQVAVKEEVP#QQPKA---RIGLDHFNFLSVLGKGNFGKVM 802 |
| Hydra vulgaris | Query 335 KLTDFNFLMVLGKGSFGKVM 354 || || || |+||||||||| Sbjct 338 KLEDFTFLKVIGKGSFGKVM 357 |
| Plasmodium yoelii yoelii str. 17XNL | Query 300 ELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 ++ +| +| +| | | | +#|+ ||| +|||| |+||||+|||+ Sbjct 370 DMHEKSKKKRL----RKFIPLSNKK#KR------RVKPDNFNFLKVIGKGSYGKVL 414 |
| Medicago truncatula | Query 302 RQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKV 353 +|| +|| + |+ +| | + +# | + + | +|| || ++|+| |||| Sbjct 540 KQKRQKAVVTPSNSKKRSSMKSK#HQKFSYTEIVNITD-NFKTIIGEGGFGKV 590 |
| Neosartorya fischeri NRRL 181 | Query 297 GNVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | + +|+ ++ + | +| | # | |+ | |||| |||||+||||| Sbjct 743 GMPQQQQQQQQQAVAPMQQQVAVKEEI-#-PPQQPKVRIGLDHFNFLAVLGKGNFGKVM 798 |
| Aspergillus terreus NIH2624 | Query 312 PAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | + ++ |+ # | + |+ | |||| |||||+||||| Sbjct 747 PVMQQQVAVKEEV#PPPQPKV-RIGLDHFNFLAVLGKGNFGKVM 788 |
| Coccidioides immitis RS | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 || | |||| |||||+||||| Sbjct 740 RVGLDHFNFLAVLGKGNFGKVM 761 |
| Plasmodium berghei strain ANKA | Query 298 NVELRQKFEKAKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ + +||+| | | | +#|+ |+| +|||| |+||||+|||+ Sbjct 259 NLYIHDMYEKSKKKRL-RKFIPLSNKK#KR------RIKPDNFNFLKVIGKGSYGKVL 308 |
| Blumeria graminis | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 |+ | |||| |||||+||||| Sbjct 826 RIGLDHFNFLAVLGKGNFGKVM 847 |
| Fundulus heteroclitus | Query 319 SPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |||+ # ++ | +||+|| |+||||||||+ Sbjct 78 SPSQQI#NLGPSSNPSAKPSDFHFLKVIGKGSFGKVL 113 |
| Neurospora crassa | Query 333 RVKLTDFNFLMVLGKGSFGKVM 354 |+ | |||| |||||+||||| Sbjct 811 RIGLDHFNFLAVLGKGNFGKVM 832 |
| Tuber borchii | Query 308 AKLGPAGNKVISPSEDR#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 |+ | |+ | # +|+ ++ | |||| |||||+||||| Sbjct 784 AEKQPPPPPVLEPQHVV#SRPT----KIGLDHFNFLAVLGKGNFGKVM 826 |
| Ashbya gossypii ATCC 10895 | Query 308 AKLGPAGNKVISPSEDR-#KQPSNNLDRVKLTDFNFLMVLGKGSFGKVM 354 | | | + + |+ | #|+ + +| | || | |||||+||||+ Sbjct 790 APLSPPKAQPVQPASGRH#KRKTPKRRKVSLDDFILLKVLGKGNFGKVL 837 |
[Site 3] KAKLGPAGNK316-VISPSEDRKQ
Lys316 Val
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Lys307 | Ala308 | Lys309 | Leu310 | Gly311 | Pro312 | Ala313 | Gly314 | Asn315 | Lys316 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Val317 | Ile318 | Ser319 | Pro320 | Ser321 | Glu322 | Asp323 | Arg324 | Lys325 | Gln326 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| NVPIPEGDEDGNVELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLG |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Oryctolagus cuniculus | 124.00 | 5 | KPCA_RABIT Protein kinase C alpha type (PKC-alpha) |
| 2 | Rattus norvegicus | 122.00 | 5 | PREDICTED: similar to Protein kinase C alpha type |
| 3 | Homo sapiens | 121.00 | 11 | aging-associated gene 6 protein |
| 4 | N/A | 121.00 | 11 | - |
| 5 | Mus musculus | 121.00 | 8 | protein kinase C |
| 6 | Canis familiaris | 121.00 | 5 | PREDICTED: similar to Protein kinase C, alpha type |
| 7 | Bos taurus | 121.00 | 4 | protein kinase C, alpha |
| 8 | synthetic construct | 121.00 | 1 | protein kinase C alpha |
| 9 | Gallus gallus | 109.00 | 3 | protein kinase C, alpha |
| 10 | Monodelphis domestica | 108.00 | 4 | PREDICTED: similar to protein kinase C |
| 11 | Latimeria chalumnae | 99.80 | 2 | protein kinase C alpha |
| 12 | Xenopus tropicalis | 99.80 | 1 | hypothetical protein LOC780209 |
| 13 | Xenopus laevis | 91.30 | 1 | protein kinase C, alpha |
| 14 | Protopterus dolloi | 87.40 | 2 | protein kinase C alpha |
| 15 | Takifugu rubripes | 74.70 | 1 | protein kinase C, alpha type |
| 16 | Scyliorhinus canicula | 70.10 | 2 | protein kinase C alpha |
| 17 | Danio rerio | 68.20 | 7 | protein kinase C, beta 1 |
| 18 | Tetraodon nigroviridis | 66.20 | 3 | unnamed protein product |
| 19 | Macaca mulatta | 59.30 | 10 | PREDICTED: protein kinase C, beta isoform 1 |
| 20 | Petromyzon marinus | 58.90 | 1 | protein kinase C |
| 21 | Myxine glutinosa | 45.40 | 1 | protein kinase C |
| 22 | Macaca fascicularis | 38.90 | 1 | KPCG_MACFA Protein kinase C gamma type (PKC-gamma) |
| 23 | Branchiostoma lanceolatum | 37.70 | 1 | protein kinase C |
| 24 | Anopheles gambiae str. PEST | 37.70 | 1 | ENSANGP00000009078 |
| 25 | Bombyx mori | 37.40 | 1 | conventional protein kinase C |
| 26 | Apis mellifera | 36.20 | 1 | PREDICTED: similar to Protein C kinase 53E CG6622- |
| 27 | Aedes aegypti | 35.00 | 1 | protein kinase c |
| 28 | Drosophila melanogaster | 32.70 | 4 | Protein C kinase 53E CG6622-PA, isoform A |
Top-ranked sequences
| organism | matching |
|---|---|
| Oryctolagus cuniculus | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| Rattus norvegicus | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||+||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 287 NVPIPEGDEEGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| Homo sapiens | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||+||+|||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 287 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| N/A | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||+||+|||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 273 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 332 |
| Mus musculus | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||+||+|||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 287 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| Canis familiaris | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||+||||||||||||||||||||#||||||||+||||||||||||||||||||| Sbjct 205 NVPIPEGDEEGNVELRQKFEKAKLGPAGNK#VISPSEDRRQPSNNLDRVKLTDFNFLMVLG 264 |
| Bos taurus | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||+||||||||||||||||||||#||||||||+||||||||||||||||||||| Sbjct 287 NVPIPEGDEEGNVELRQKFEKAKLGPAGNK#VISPSEDRRQPSNNLDRVKLTDFNFLMVLG 346 |
| synthetic construct | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||+||+|||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 287 NVPIPEGDEEGNMELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |
| Gallus gallus | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 344 |||||+ ||||| |||||||||||||||||#||+||||| |||||||||||||||||| Sbjct 287 NVPIPDADEDGNAELRQKFEKAKLGPAGNK#VITPSEDRNSSVPSNNLDRVKLTDFNFLMV 346 Query 345 LG 346 || Query 345 LG 346 |
| Monodelphis domestica | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||||||+||+||||||||||||| |||#||| |+||| |+|||||||||||||||||| Sbjct 287 NVPIPEGDEEGNMELRQKFEKAKLGPVGNK#VISSSDDRK-PTNNLDRVKLTDFNFLMVLG 345 |
| Latimeria chalumnae | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 344 |||| | | |||||||||||||||||||+|#|||| |+|| |||||||||||||||||| Sbjct 209 NVPISEAD-DGNVELRQKFEKAKLGPAGSK#VISPVEERKSSTPSNNLDRVKLTDFNFLMV 267 Query 345 LG 346 || Query 345 LG 346 |
| Xenopus tropicalis | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 344 |||||| ++|||+|||||||||||||||||#||||+++|+ ||||+| |+||||+|||| Sbjct 291 NVPIPEEEDDGNIELRQKFEKAKLGPAGNK#VISPTDERRPYVPSNNIDSVRLTDFSFLMV 350 Query 345 LG 346 || Query 345 LG 346 |
| Xenopus laevis | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQ--PSNNLDRVKLTDFNFLMV 344 |||||| | |||+|||||||||||||||||#||+|+ +|+ ||||+| ++|||| |||| Sbjct 291 NVPIPEAD-DGNLELRQKFEKAKLGPAGNK#VINPTGERRPYIPSNNIDSIRLTDFCFLMV 349 Query 345 LG 346 || Query 345 LG 346 |
| Protopterus dolloi | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||||+ | |||| ||||||||+||||| |#|||| | ||||| || ||||+|||| Sbjct 207 NVPIPDAD-DGNVGLRQKFEKARLGPAGKK#VISPERKSSLPLNNLDRFKLEDFNFVMVLG 265 |
| Takifugu rubripes | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRK--QPSNNLDRVKLTDFNFLMV 344 |||||| | | |+|||||||||||| | |#||+||+ |+ || |+|||+| ||||| + Sbjct 285 NVPIPEVD-DVNLELRQKFEKAKLGQ-GKK#VITPSDHRRFSLPSGNMDRVRLNDFNFLAL 342 Query 345 LG 346 || Query 345 LG 346 |
| Scyliorhinus canicula | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 |||| | ||| |||+||||||||||| |# | + |+|+|| | | ||||||||| Sbjct 220 NVPIIEDDEDS--ELRKKFEKAKLGPAGKK#AI--EKKPSSPTNDLDHVHLEDFNFLMVLG 275 |
| Danio rerio | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSN-NLDRVKLTDFNFLMVL 345 |||+| |+|| |||||||+||+||+ # | + | || | ||+||+|||||||| Sbjct 286 NVPVPPEGEEGNEELRQKFERAKIGPSKTD#GSSSNAISKFDSNGNRDRMKLSDFNFLMVL 345 Query 346 G 346 | Query 346 G 346 |
| Tetraodon nigroviridis | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK--#VISPSEDRKQPSNNLDRVKLTDFNFLMV 344 |||+| |+|| |||||||+||+|| | # + + | + | ||+|| ||||||| Sbjct 223 NVPVPPEGEEGNEELRQKFERAKIGPGKNTDG#KSANAASRFDSNGNQDRMKLADFNFLMV 282 Query 345 LG 346 || Query 345 LG 346 |
| Macaca mulatta | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#V----ISPSEDRKQPSNNLDRVKLTDFNFL 342 |||+| +|| |||||||+||+ | |#| + + + + | ||+|||||||| Sbjct 287 NVPVPPEGSEGNEELRQKFERAKIS-QGTK#VPEEKTTNTVSKFDNNGNRDRMKLTDFNFL 345 Query 343 MVLG 346 |||| Query 343 MVLG 346 |
| Petromyzon marinus | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISP--SEDRKQPS-------NNLDRVKLT 337 |||| |||+ |+|+|||||+|||+ # + | |++|+ | |+|||| Sbjct 217 NVPIAPDIEDGDTEMRRKFEKARLGPS---#-VKPRASDERRANSLSAILNNANVDRVKAD 272 Query 338 DFNFLMVLG 346 ||||||||| Query 338 DFNFLMVLG 346 |
| Myxine glutinosa | Query 287 NVPI-PEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPS---NNLDRVKLTDFNFL 342 |||+ |||+| +||||+ +++++ + # ||++|+ | + |||| | || || Sbjct 208 NVPVAPEGEE--GLELRQRLQRSQIARSDKN#KQSPAKDQPSDSASLSGLDRVNLEDFVFL 265 Query 343 MVLG 346 ||| Sbjct 266 TVLG 269 |
| Macaca fascicularis | Query 287 NVPIPEGDEDGNVELRQKFE----------KAKLGPAGNK#VISPSEDRKQPSN-----NL 331 |||+ + | | | |||| + ++||+ + #+ ||| | + Sbjct 287 NVPVADAD---NCSLLQKFEACNYPLELYERVRMGPSSSP#IPSPSPSPTDPKRCFFGASP 343 Query 332 DRVKLTDFNFLMVLG 346 |+ ++||+|||||| Sbjct 344 GRLHISDFSFLMVLG 358 |
| Branchiostoma lanceolatum | Query 287 NVPIPEGDEDGNV-ELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVL 345 |||| ||+ || +|++ +| || +# ||+ | || +| |||||||| Sbjct 218 NVPI--ADEEENVAKLKEHLQKQKLDEQRKQ#KSKRSEECNIGS--LDHMKAADFNFLMVL 273 Query 346 G 346 | Query 346 G 346 |
| Anopheles gambiae str. PEST | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSN--NLDRVKLTDFNFLMV 344 |||+|| | |+|+ + | + |# | |+ | | | ++ |||||||| Sbjct 227 NVPVPEEGAD-LVQLKSQMRKTSI----TK#KIPMMGDKDVPHNMTKKDVIRATDFNFLMV 281 Query 345 LG 346 || Query 345 LG 346 |
| Bombyx mori | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSN--NLDRVKLTDFNFLMV 344 |||+|| | | | + + | +# | ||+ | | | ++ |||||+|| Sbjct 290 NVPVPEEGAD----LVQLKNQMRATTVGAR#RPPPPPDREVPHNVAAADVIRATDFNFIMV 345 Query 345 LG 346 || Query 345 LG 346 |
| Apis mellifera | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSN--NLDRVKLTDFNFLMV 344 |||+|| | ||+ | | |# + ++|++ | | | ++ +||||||| Sbjct 304 NVPVPEEGVD-LAELKMKPSPQKTSVT--K#KTTTTQDKEVPHNMGKSDLIRASDFNFLMV 360 Query 345 LG 346 || Query 345 LG 346 |
| Aedes aegypti | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSN--NLDRVKLTDFNFLMV 344 |||+|| | |+|+ + | + #+ |+ | | | ++ |||||||| Sbjct 235 NVPVPEEGTD-LVQLKSQMRKTSISKKAPV#LC----DKDVPHNMGKKDVIRATDFNFLMV 289 Query 345 LG 346 || Query 345 LG 346 |
| Drosophila melanogaster | Query 287 NVPIPEGDEDGNVELRQKFEKAKLGPAGNK#VISPSEDRKQPSNNLDRVKLTDFNFLMVLG 346 ||| + || ++|+|| + | #++ |+ |+ | ++ |||||+ ||| Sbjct 296 NVPCAD-DEQDLLKLKQKPSQKK------P#MVMRSDTNTHTSSKKDMIRATDFNFIKVLG 348 |
* References
[PubMed ID: 19235902] Haughian JM, Bradford AP, Protein kinase C alpha (PKCalpha) regulates growth and invasion of endometrial cancer cells. J Cell Physiol. 2009 Jul;220(1):112-8.
[PubMed ID: 8900191] ... Li Y, Davis KL, Sytkowski AJ, Protein kinase C-epsilon is necessary for erythropoietin's up-regulation of c-myc and for factor-dependent DNA synthesis. Evidence for discrete signals for growth and differentiation. J Biol Chem. 1996 Oct 25;271(43):27025-30.
[PubMed ID: 3808073] ... Ohno S, Kawasaki H, Imajoh S, Suzuki K, Inagaki M, Yokokura H, Sakoh T, Hidaka H, Tissue-specific expression of three distinct types of rabbit protein kinase C. Nature. 1987 Jan 8-14;325(7000):161-6.