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XSB2212 : Integrin, beta 1b.1 [Danio rerio]

[ CaMP Format ]

This entry is computationally expanded from SB0063

* Basic Information

OrganismDanio rerio (zebrafish)
Protein NamesIntegrin beta; integrin; beta 1b.1
Gene Namesitgb1b.1
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
AAI63260 N/A 566771 B3DIV2_DANRE N/A N/A N/A dre:566771

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 787 aa

Average Mass: 86.548 kDa

Monoisotopic Mass: 86.491 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Integrin_beta 1. 34458877.28.7e-261
EGF_2 1. 46049413.50.082
EGF_2 2. 51054718.70.02
EGF_2 3. 55458428.52.8e-05
EGF_2 4. 59362334.44.5e-07
Integrin_B_tail 1. 633717105.51.8e-28
Integrin_b_cyt 1. 741786106.87.3e-29
--- cleavage 780 (inside Integrin_b_cyt 741..786) ---
--- cleavage 766 (inside Integrin_b_cyt 741..786) ---
--- cleavage 778 (inside Integrin_b_cyt 741..786) ---
--- cleavage 767 (inside Integrin_b_cyt 741..786) ---

3. Sequence Information

Fasta Sequence: XSB2212.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

4 [sites]

Cleavage sites (±10aa)

[Site 1] IYKSAVTTVV780-NPRYEGK

Val780 Asn

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ile771Tyr772Lys773Ser774Ala775Val776Thr777Thr778Val779Val780
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Asn781Pro782Arg783Tyr784Glu785Gly786Lys787---

Sequence conservation (by blast)

[Site 2] KEKNNAKWDT766-GENPIYKSAV

Thr766 Gly

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys757Glu758Lys759Asn760Asn761Ala762Lys763Trp764Asp765Thr766
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Gly767Glu768Asn769Pro770Ile771Tyr772Lys773Ser774Ala775Val776

Sequence conservation (by blast)

[Site 3] NPIYKSAVTT778-VVNPRYEGK

Thr778 Val

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Asn769Pro770Ile771Tyr772Lys773Ser774Ala775Val776Thr777Thr778
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Val779Val780Asn781Pro782Arg783Tyr784Glu785Gly786Lys787-

Sequence conservation (by blast)

[Site 4] EKNNAKWDTG767-ENPIYKSAVT

Gly767 Glu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu758Lys759Asn760Asn761Ala762Lys763Trp764Asp765Thr766Gly767
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Glu768Asn769Pro770Ile771Tyr772Lys773Ser774Ala775Val776Thr777

Sequence conservation (by blast)

* References

[PubMed ID: 12477932] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.