logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2215 : rCG35442 [Rattus norvegicus]

[ CaMP Format ]

This entry is computationally expanded from SB0043

* Basic Information

OrganismRattus norvegicus (Norway rat)
Protein NamesrCG35442
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
EDM06324 N/A N/A N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 583 aa

Average Mass: 64.528 kDa

Monoisotopic Mass: 64.485 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Integrin_beta 1. 2256390.33.3e-114
EGF_2 1. 25829219.20.017
EGF_2 2. 30734231.92.6e-06
EGF_2 3. 34937926.50.00011
EGF_2 4. 38841923.80.00071
Integrin_B_tail 1. 429513125.22.1e-34
Integrin_b_cyt 1. 537582106.87.1e-29
--- cleavage 562 (inside Integrin_b_cyt 537..582) ---
--- cleavage 580 (inside Integrin_b_cyt 537..582) ---
--- cleavage 568 (inside Integrin_b_cyt 537..582) ---
--- cleavage 556 (inside Integrin_b_cyt 537..582) ---

3. Sequence Information

Fasta Sequence: XSB2215.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

4 [sites]

Cleavage sites (±10aa)

[Site 1] EERARAKWDT562-ANNPLYKEAT

Thr562 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu553Glu554Arg555Ala556Arg557Ala558Lys559Trp560Asp561Thr562
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala563Asn564Asn565Pro566Leu567Tyr568Lys569Glu570Ala571Thr572

Sequence conservation (by blast)

[Site 2] ATSTFTNITY580-RGT

Tyr580 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ala571Thr572Ser573Thr574Phe575Thr576Asn577Ile578Thr579Tyr580
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Arg581Gly582Thr583-------

Sequence conservation (by blast)

[Site 3] KWDTANNPLY568-KEATSTFTNI

Tyr568 Lys

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys559Trp560Asp561Thr562Ala563Asn564Asn565Pro566Leu567Tyr568
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Lys569Glu570Ala571Thr572Ser573Thr574Phe575Thr576Asn577Ile578

Sequence conservation (by blast)

[Site 4] EFAKFEEERA556-RAKWDTANNP

Ala556 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu547Phe548Ala549Lys550Phe551Glu552Glu553Glu554Arg555Ala556
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Arg557Ala558Lys559Trp560Asp561Thr562Ala563Asn564Asn565Pro566

Sequence conservation (by blast)

* References

[PubMed ID: 15632090] Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G, Gene and alternative splicing annotation with AIR. Genome Res. 2005 Jan;15(1):54-66.