CT0108 : calpastatin isoform b [Rattus norvegicus]
[ CaMP Format ]
* Basic Information
| Organism | Rattus norvegicus (Norway rat) |
| Protein Names | calpastatin isoform b; Calpastatin (probably multiple splicing products); Calpastatin; Calpain inhibitor |
| Gene Names | Cast; calpastatin |
| Gene Locus | 2q11; chromosome 2 |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| NP_001028887 | NM_001033715 | 25403 | Q5BK19 | N/A | N/A | N/A | rno:25403 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 675 aa
Average Mass: 73.156 kDa
Monoisotopic Mass: 73.112 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Calpain_inhib 1. | 88 | 224 | 101.6 | 2.6e-27 |
| Calpain_inhib 2. | 232 | 357 | 212.6 | 1e-60 |
| Calpain_inhib 3. | 368 | 468 | 146.4 | 8.8e-41 |
| Calpain_inhib 4. | 479 | 605 | 216.1 | 9.2e-62 |
3. Sequence Information
Fasta Sequence: CT0108.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* References
[PubMed ID: 19020623] Hanna RA, Campbell RL, Davies PL, Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin. Nature. 2008 Nov 20;456(7220):409-12.