logo CaMPDB: Calpain for Modulatory Proteolysis Database

SB0017 : CAPNS1, 30K, Calpain regulatory subunit

[ CaMP Format ]

* Basic Information

OrganismGallus gallus (chicken)
Protein Namescalpain small subunit, partial [Gallus gallus]; calpain small subunit; 3.4.22.52 {ECO:0000313|EMBL:BAA22638.1}
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
BAA22638 N/A N/A O42134 N/A N/A N/A gga:

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 214 aa

Average Mass: 23.915 kDa

Monoisotopic Mass: 23.900 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
--- cleavage 32 ---
--- cleavage 35 ---
EF-hand domain pair 1. 6211317.00.1
EF-hand domain pair 2. 12313931.00.0
Cytoskeletal-regulatory complex EF hand 1. 16517955.00.1
EF hand 1. 1872004.00.1

3. Sequence Information

Fasta Sequence: SB0017.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Source Reference: [PubMed ID: 2829834] Crawford C, Willis AC, Gagnon J, The effects of autolysis on the structure of chicken calpain II. Biochem J. 1987 Dec 1;248(2):579-88.

Cleavage sites (±10aa)

[Site 1] NPEPPPPRSH32-VSMVDPNESE

His32 Val

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Asn23Pro24Glu25Pro26Pro27Pro28Pro29Arg30Ser31His32
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Val33Ser34Met35Val36Asp37Pro38Asn39Glu40Ser41Glu42

Sequence conservation (by blast)

[Site 2] PPPPRSHVSM35-VDPNESEEVR

Met35 Val

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Pro26Pro27Pro28Pro29Arg30Ser31His32Val33Ser34Met35
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Val36Asp37Pro38Asn39Glu40Ser41Glu42Glu43Val44Arg45

Sequence conservation (by blast)

* References

None.