logo CaMPDB: Calpain for Modulatory Proteolysis Database

SB0029 : Troponin T3, fast skeletal muscle, TnTf

[ CaMP Format ]

* Basic Information

OrganismOryctolagus cuniculus (rabbit)
Protein NamesRecName: Full=Troponin T, fast skeletal muscle; Short=TnTf; AltName: Full=Fast skeletal muscle troponin T; Short=fTnT; Troponin T, fast skeletal muscle; TnTf; Fast skeletal muscle troponin T; fTnT
Gene NamesTNNT3
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
P02641 N/A N/A P02641 N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 279 aa

Average Mass: 33.034 kDa

Monoisotopic Mass: 33.014 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Troponin 1. 145819.07.9
--- cleavage 65 ---
Troponin 2. 21226544.01.6

3. Sequence Information

Fasta Sequence: SB0029.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites] cleaved by Calpain 11

Source Reference: [PubMed ID: 6746610] Ohtsuki I, Shiraishi F, Suenaga N, Miyata T, Tanokura M, A 26K fragment of troponin T from rabbit skeletal muscle. J Biochem. 1984 May;95(5):1337-42.

Cleavage sites (±10aa)

[Site 1] EEEKPRPKLT65-APKIPEGEKV

Thr65 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu56Glu57Glu58Lys59Pro60Arg61Pro62Lys63Leu64Thr65
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala66Pro67Lys68Ile69Pro70Glu71Gly72Glu73Lys74Val75

Sequence conservation (by blast)

* References

[PubMed ID: 320204] Pearlstone JR, Johnson P, Carpenter MR, Smillie LB, Primary structure of rabbit skeletal muscle troponin-T. Sequence determination of the NH2-terminal fragment CB3 and the complete sequence of troponin-T. J Biol Chem. 1977 Feb 10;252(3):983-9.

» More (3)