SB0045 : MBP, Myelin basic protein
[ CaMP Format ]
* Basic Information
| Organism | Bos taurus (cattle) |
| Protein Names | RecName: Full=Myelin basic protein; Short=MBP; AltName: Full=20 kDa microtubule-stabilizing protein; AltName: Full=Myelin A1 protein; Myelin basic protein; 20 kDa microtubule-stabilizing protein; Myelin A1 protein; MBP |
| Gene Names | MBP |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 169 aa
Average Mass: 18.323 kDa
Monoisotopic Mass: 18.312 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Myelin basic protein 1. | 13 | 169 | 1.0 | 8.8 |
| --- cleavage 16 (inside Myelin basic protein 13..169) --- | ||||
| --- cleavage 68 (inside Myelin basic protein 13..169) --- | ||||
| --- cleavage 93 (inside Myelin basic protein 13..169) --- | ||||
| --- cleavage 96 (inside Myelin basic protein 13..169) --- | ||||
3. Sequence Information
Fasta Sequence: SB0045.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
4 [sites] cleaved by Calpain 2
Source Reference: [PubMed ID: 2472383] Tsubata T, Takahashi K, Limited proteolysis of bovine myelin basic protein by calcium-dependent proteinase from bovine spinal cord. J Biochem. 1989 Jan;105(1):23-8.
Cleavage sites (±10aa)
[Site 1] SQRSKYLASA16-STMDHARHGF
Ala16 
Ser
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Ser7 | Gln8 | Arg9 | Ser10 | Lys11 | Tyr12 | Leu13 | Ala14 | Ser15 | Ala16 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser17 | Thr18 | Met19 | Asp20 | His21 | Ala22 | Arg23 | His24 | Gly25 | Phe26 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| AAQKRPSQRSKYLASASTMDHARHGFLPRHRDTGILDSLGRFFGSD |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Bos taurus | 95.50 | 1 | MBP protein |
| 2 | N/A | 95.10 | 14 | 1003243A protein 21.5K,myelin basic |
| 3 | Mus musculus | 90.10 | 7 | Golli-mbp isoform 2 |
| 4 | Bos taurus | 89.40 | 1 | AF226693_1 myelin basic protein |
| 5 | Homo sapiens | 88.60 | 7 | Golli-mbp isoform 2 |
| 6 | Canis familiaris | 87.40 | 2 | PREDICTED: similar to Golli-mbp isoform 2 isoform |
| 7 | Sus scrofa | 87.40 | 1 | myelin basic protein |
| 8 | Pongo pygmaeus | 85.90 | 2 | hypothetical protein |
| 9 | synthetic construct | 85.50 | 2 | myelin basic protein |
| 10 | Homo sapiens | 85.50 | 1 | myelin basic protein isoform 2 |
| 11 | Rattus norvegicus | 83.60 | 8 | myelin basic protein isoform 4 |
| 12 | Rattus norvegicus | 83.20 | 1 | myelin basic protein isoform 5 |
| 13 | Cavia porcellus | 76.60 | 1 | myelin basic protein; MBP |
| 14 | Gallus gallus | 58.20 | 1 | myelin basic protein |
| 15 | Xenopus tropicalis | 55.10 | 1 | hypothetical protein LOC549346 |
| 16 | Xenopus laevis | 51.60 | 1 | myelin basic protein |
| 17 | Xenopus laevis | 51.60 | 1 | hypothetical protein LOC734401 |
| 18 | Gekko japonicus | 51.20 | 1 | GekBS065P |
| 19 | Heterodontus francisci | 40.00 | 1 | MBP_HETFR Myelin basic protein (MBP) gi |
| 20 | cattle, brain, Peptide Partial, 13 aa, segment 1 of 3 | 30.00 | 1 | clathrin assembly protein=myelin basic protein (M |
Top-ranked sequences
| organism | matching |
|---|---|
| Bos taurus | Query 1 AAQKRPSQRSKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 ||||||||||||||||#|||||||||||||||||||||||||||||| Query 1 AAQKRPSQRSKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |
| N/A | Query 1 AAQKRPSQRSKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 ||||||||||||||||#|||||||||||||||||||||||||||||| Query 1 AAQKRPSQRSKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |
| Mus musculus | Query 1 AAQKRPSQRSKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||||||||||||+|#||||||||||||||||||||||+|||| | Sbjct 135 ASQKRPSQRSKYLATA#STMDHARHGFLPRHRDTGILDSIGRFFSGD 180 |
| Bos taurus | Query 4 KRPSQRSKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |||||||||||||#|||||||||||||||||||||||||||||| Query 4 KRPSQRSKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |
| Homo sapiens | Query 1 AAQKRPSQR--SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||||||| |||||+|#||||||||||||||||||||||+||||| | Sbjct 135 ASQKRPSQRHGSKYLATA#STMDHARHGFLPRHRDTGILDSIGRFFGGD 182 |
| Canis familiaris | Query 1 AAQKRPSQR--SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||||||| |||||||#| |||||||||||||||||||||||||| | Sbjct 134 ASQKRPSQRHGSKYLASA#SAMDHARHGFLPRHRDTGILDSLGRFFGGD 181 |
| Sus scrofa | Query 1 AAQKRPSQR--SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||||||| |||||||#||||||||||||||||||||||||||||+| Sbjct 2 ASQKRPSQRHGSKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGAD 49 |
| Pongo pygmaeus | Query 1 AAQKRPSQR--SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||||||| |||||+|#||||||||||||||||||||||+||||| | Sbjct 2 ASQKRPSQRHGSKYLATA#STMDHARHGFLPRHRDTGILDSIGRFFGGD 49 |
| synthetic construct | Query 1 AAQKRPSQR--SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||||||| |||||+|#||||||||||||||||||||||+||||| | Sbjct 2 ASQKRPSQRHGSKYLATA#STMDHARHGFLPRHRDTGILDSIGRFFGGD 49 |
| Homo sapiens | Query 1 AAQKRPSQR--SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||||||| |||||+|#||||||||||||||||||||||+||||| | Sbjct 2 ASQKRPSQRHGSKYLATA#STMDHARHGFLPRHRDTGILDSIGRFFGGD 49 |
| Rattus norvegicus | Query 1 AAQKRPSQR--SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||||||| |||||+|#||||||||||||||||||||||+|||| | Sbjct 2 ASQKRPSQRHGSKYLATA#STMDHARHGFLPRHRDTGILDSIGRFFSGD 49 |
| Rattus norvegicus | Query 1 AAQKRPSQR--SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||||||| |||||+|#||||||||||||||||||||||+|||| | Sbjct 2 ASQKRPSQRHGSKYLATA#STMDHARHGFLPRHRDTGILDSIGRFFSGD 49 |
| Cavia porcellus | Query 7 SQR--SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 ||| |||||+|#||||||||||||||||||||||+||||||| Sbjct 1 SQRHGSKYLATA#STMDHARHGFLPRHRDTGILDSIGRFFGSD 42 |
| Gallus gallus | Query 1 AAQKRPSQR-SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||| | | +|||#|| |||||| |||||+|+||||||||| | Sbjct 2 ASQKRSSFRHGSKMASA#STTDHARHG-SPRHRDSGLLDSLGRFFGGD 47 |
| Xenopus tropicalis | Query 1 AAQKRPSQRSKYLASA#STMDHARHGFLP--RHRDTGILDSLGRFFG 44 |+|| || +|+|#|| ||+|||+ ||||+|+||||||||| Sbjct 132 ASQKLSRHGSKQMATA#STSDHSRHGYGAHGRHRDSGLLDSLGRFFG 177 |
| Xenopus laevis | Query 10 SKYLASA#STMDHARHGFLP--RHRDTGILDSLGRFFGSD 46 || +|+|#|| ||+|||+ ||||+|+||||||||| + Sbjct 12 SKQMATA#STYDHSRHGYGAHGRHRDSGLLDSLGRFFGGE 50 |
| Xenopus laevis | Query 10 SKYLASA#STMDHARHGFLP--RHRDTGILDSLGRFFGSD 46 || +|+|#|| ||+|||+ ||||+|+||||||||| + Sbjct 12 SKQMATA#STSDHSRHGYGAHGRHRDSGLLDSLGRFFGGE 50 |
| Gekko japonicus | Query 1 AAQKRPSQR-SKYLASA#STMDHARHGFLPRHRDTGILDSLGRFFGSD 46 |+||| | | ||+|#||+|||||| |+|+ +||||||||| | Sbjct 2 ASQKRSSFRHGSKLATA#STIDHARHGSPRRYREPSLLDSLGRFFGGD 48 |
| Heterodontus francisci | Query 13 LASA#STMDHARH--GFLPRHRDTGILDSLGRFFGSD 46 +|||#|| ||++ | | ||+|+|| ||+||| + Sbjct 1 MASA#STSDHSKQAGGAHSRQRDSGLLDQLGKFFGQE 36 |
| cattle, brain, Peptide Partial, 13 aa, segment 1 of 3 | Query 30 HRDTGILDSLGRF 42 ||||||||||||| Query 30 HRDTGILDSLGRF 42 |
[Site 2] HHAARTTHYG68-SLPQKAQGHR
Gly68 Ser
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| His59 | His60 | Ala61 | Ala62 | Arg63 | Thr64 | Thr65 | His66 | Tyr67 | Gly68 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser69 | Leu70 | Pro71 | Gln72 | Lys73 | Ala74 | Gln75 | Gly76 | His77 | Arg78 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LGRFFGSDRGAPKRGSGKDGHHAARTTHYGSLPQKAQGHRPQDENPVVHFFKNIVTPRTP |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 125.00 | 22 | MBP_BOVIN Myelin basic protein (MBP) (Myelin A1 p |
| 2 | Bos taurus | 120.00 | 1 | MBP protein |
| 3 | Sus scrofa | 117.00 | 1 | myelin basic protein |
| 4 | Canis familiaris | 112.00 | 2 | PREDICTED: similar to Myelin basic protein (MBP) |
| 5 | Cavia porcellus | 107.00 | 1 | myelin basic protein; MBP |
| 6 | Pongo pygmaeus | 106.00 | 2 | hypothetical protein |
| 7 | Homo sapiens | 105.00 | 7 | Golli-mbp isoform 1 |
| 8 | synthetic construct | 103.00 | 3 | myelin basic protein |
| 9 | Mus musculus | 99.40 | 7 | Golli-mbp isoform 1 |
| 10 | Rattus norvegicus | 95.50 | 8 | myelin basic protein isoform 2 |
| 11 | Rattus norvegicus | 95.50 | 1 | myelin basic protein isoform 5 |
| 12 | Homo sapiens | 89.00 | 1 | myelin basic protein isoform 2 |
| 13 | Gallus gallus | 84.30 | 1 | myelin basic protein |
| 14 | Gekko japonicus | 71.20 | 1 | GekBS065P |
| 15 | Xenopus laevis | 66.20 | 1 | hypothetical protein LOC734401 |
| 16 | Xenopus laevis | 65.50 | 1 | myelin basic protein |
| 17 | cattle, brain, Peptide Partial, 21 aa, segment 1 of 2 | 42.00 | 1 | myelin basic protein, MBP=20 kda microtubule stab |
| 18 | Bos taurus | 38.90 | 1 | AF226693_1 myelin basic protein |
| 19 | cattle, brain, Peptide Partial, 15 aa, segment 2 of 3 | 35.40 | 1 | clathrin assembly protein=myelin basic protein (M |
| 20 | Heterodontus francisci | 33.90 | 1 | MBP_HETFR Myelin basic protein (MBP) gi |
| 21 | Tetraodon nigroviridis | 33.50 | 1 | unnamed protein product |
| 22 | Danio rerio | 30.00 | 1 | myelin basic protein |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 |
| Bos taurus | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 ||||||||||||||||||||||||||||||#||||||| ||||||||||||||||||||| Sbjct 60 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQHGRPQDENPVVHFFKNIVTPRTP 119 |
| Sus scrofa | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 ||||||+|||||||||||||||||||||||#||||||| ||||||||||||||||||||| Sbjct 42 LGRFFGADRGAPKRGSGKDGHHAARTTHYG#SLPQKAQHGRPQDENPVVHFFKNIVTPRTP 101 |
| Canis familiaris | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 |||||| ||| ||||||||||||||| |||#|||||+| ||||||||||||||||||||| Sbjct 42 LGRFFGGDRGVPKRGSGKDGHHAARTAHYG#SLPQKSQHGRPQDENPVVHFFKNIVTPRTP 101 |
| Cavia porcellus | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 +|||||||| ||||||||| ||||||||||#|||||+| | ||||||||||||||||||| Sbjct 35 IGRFFGSDRAAPKRGSGKDSHHAARTTHYG#SLPQKSQ--RSQDENPVVHFFKNIVTPRTP 92 |
| Pongo pygmaeus | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 +||||| |||||||||||| |||||| |||#|||||+ | | ||||||||||||||||||| Sbjct 42 IGRFFGGDRGAPKRGSGKDSHHAARTAHYG#SLPQKSHG-RTQDENPVVHFFKNIVTPRTP 100 |
| Homo sapiens | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 +||||| |||||||||||| || ||| |||#|||||+ | | ||||||||||||||||||| Sbjct 175 IGRFFGGDRGAPKRGSGKDSHHPARTAHYG#SLPQKSHG-RTQDENPVVHFFKNIVTPRTP 233 |
| synthetic construct | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 +||||| |||||||||||| || ||| |||#|||||+ | | ||||||||||||||||||| Sbjct 42 IGRFFGGDRGAPKRGSGKDSHHPARTAHYG#SLPQKSHG-RTQDENPVVHFFKNIVTPRTP 100 |
| Mus musculus | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 +|||| |||||||||||| | ||||||#|||||+| | ||||||||||||||||||| Sbjct 173 IGRFFSGDRGAPKRGSGKDSH--TRTTHYG#SLPQKSQHGRTQDENPVVHFFKNIVTPRTP 230 |
| Rattus norvegicus | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 +|||| |||||||||||| | ||||||#|||||+| | ||||||||||||||||||| Sbjct 42 IGRFFSGDRGAPKRGSGKDSH--TRTTHYG#SLPQKSQ--RTQDENPVVHFFKNIVTPRTP 97 |
| Rattus norvegicus | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 +|||| |||||||||||| | ||||||#|||||+| | ||||||||||||||||||| Sbjct 42 IGRFFSGDRGAPKRGSGKDSH--TRTTHYG#SLPQKSQ--RTQDENPVVHFFKNIVTPRTP 97 |
| Homo sapiens | Query 39 LGRFFGSDRGAPKRGSGK--------------------------DGHHAARTTHYG#SLPQ 72 +||||| ||||||||||| | || ||| |||#|||| Sbjct 42 IGRFFGGDRGAPKRGSGKVPWLKPGRSPLPSHARSQPGLCNMYKDSHHPARTAHYG#SLPQ 101 Query 73 KAQGHRPQDENPVVHFFKNIVTPRTP 98 |+ | | ||||||||||||||||||| Sbjct 102 KSHG-RTQDENPVVHFFKNIVTPRTP 126 |
| Gallus gallus | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVTPRTP 98 |||||| || |+|| ||| |||| +| |#|+||++| || |+|||||||||||+|||| Sbjct 40 LGRFFGGDRHVPRRGFGKD-IHAARASHVG#SIPQRSQHGRPGDDNPVVHFFKNIVSPRTP 98 |
| Gekko japonicus | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGH----RPQDENPVVHFFKNIVT 94 |||||| |+ |+|| || ||||| +| #||| | | |+|||||||||||+ Sbjct 41 LGRFFGGDKHVPRRG--KDYHHAARVSHVS#SLPHPRSQHGRYGRYVDDNPVVHFFKNIVS 98 Query 95 PRTP 98 |||| Query 95 PRTP 98 |
| Xenopus laevis | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGH---RPQDENPVVHFFKNIVTP 95 |||||| +| |++||||+ | +|+ + #| ||++ + | |||||||||+|||+| Sbjct 43 LGRFFGGERAVPRKGSGKEVH-MSRSGYLS#SSPQRSHYYAHGRHVDENPVVHFFRNIVSP 101 Query 96 RTP 98 ||| Query 96 RTP 98 |
| Xenopus laevis | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGH---RPQDENPVVHFFKNIVTP 95 |||||| +| |++||||+ | +|+ + #| ||++ | | |+|||||||+|||+| Sbjct 43 LGRFFGGERSVPRKGSGKEVH-MSRSGYLS#SSPQRSPYHAHGRHVDDNPVVHFFRNIVSP 101 Query 96 RTP 98 ||| Query 96 RTP 98 |
| cattle, brain, Peptide Partial, 21 aa, segment 1 of 2 | Query 39 LGRFFGSDRGAPKRGSGKDG 58 |||||||||||||||||||| Query 39 LGRFFGSDRGAPKRGSGKDG 58 |
| Bos taurus | Query 39 LGRFFGSDRGAPKRGSGK 56 |||||||||||||||||| Query 39 LGRFFGSDRGAPKRGSGK 56 |
| cattle, brain, Peptide Partial, 15 aa, segment 2 of 3 | Query 74 AQGHRPQDENPVVHF 88 ||||||||||||||| Query 74 AQGHRPQDENPVVHF 88 |
| Heterodontus francisci | Query 39 LGRFFGSD--RGAPKRGSGKDGHHAARTTHYG#SLPQKA--QGHRPQDENPVVHFFKNIVT 94 ||+||| + | |++| | |+ # || | |++ |||||||+++ Sbjct 29 LGKFFGQEGSRKVPEKGK----EPATRSVLMA#PTTHKAHQAAGRQTDDSAVVHFFKNMMS 84 Query 95 PR 96 |+ Sbjct 85 PK 86 |
| Tetraodon nigroviridis | Query 71 PQKAQGHRPQD---ENPVVHFFKNIVTPRTP 98 |||| |+ || |||||+ |||| | Sbjct 138 PQKASATSPRKRGAENAVVHFFRTIVTPAPP 168 |
| Danio rerio | Query 39 LGRFFGSDRGAPKRGSGKDGHHAARTTHYG#SLPQKAQGHRPQDENPVVHFFKNIVT 94 + |||| | |+ || ||++ # | | |||||||++ |+ Sbjct 27 ISRFFGGD----KKRKGKRPHHSS------#-------TRRRGDVNPVVHFFRSFVS 65 |
[Site 3] PVVHFFKNIV93-TPRTPPPSQG
Val93 Thr
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Pro84 | Val85 | Val86 | His87 | Phe88 | Phe89 | Lys90 | Asn91 | Ile92 | Val93 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr94 | Pro95 | Arg96 | Thr97 | Pro98 | Pro99 | Pro100 | Ser101 | Gln102 | Gly103 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| TTHYGSLPQKAQGHRPQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQKPG |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 127.00 | 21 | MBP_BOVIN Myelin basic protein (MBP) (Myelin A1 p |
| 2 | Sus scrofa | 120.00 | 1 | myelin basic protein |
| 3 | Mus musculus | 117.00 | 6 | myelin basic protein isoform 3 |
| 4 | Canis familiaris | 117.00 | 1 | PREDICTED: similar to Myelin basic protein (MBP) |
| 5 | Rattus norvegicus | 114.00 | 8 | myelin basic protein |
| 6 | Cavia porcellus | 114.00 | 1 | myelin basic protein; MBP |
| 7 | Homo sapiens | 113.00 | 6 | Golli-mbp isoform 1 |
| 8 | synthetic construct | 111.00 | 2 | myelin basic protein |
| 9 | Pongo pygmaeus | 111.00 | 2 | hypothetical protein |
| 10 | Rattus norvegicus | 102.00 | 1 | myelin basic protein isoform 5 |
| 11 | Gallus gallus | 97.40 | 1 | myelin basic protein |
| 12 | Bos taurus | 90.10 | 1 | MBP protein |
| 13 | Homo sapiens | 79.70 | 1 | myelin basic protein isoform 2 |
| 14 | Gekko japonicus | 76.60 | 1 | GekBS065P |
| 15 | Xenopus laevis | 75.10 | 1 | hypothetical protein LOC734401 |
| 16 | Xenopus laevis | 65.50 | 1 | myelin basic protein |
| 17 | Heterodontus francisci | 46.60 | 1 | MBP_HETFR Myelin basic protein (MBP) gi |
| 18 | cattle, brain, Peptide Partial, 15 aa, segment 2 of 3 | 35.80 | 1 | clathrin assembly protein=myelin basic protein (M |
| 19 | Tetraodon nigroviridis | 33.90 | 1 | unnamed protein product |
| 20 | Danio rerio | 30.80 | 1 | myelin basic protein |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 |
| Sus scrofa | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 |||||||||||| ||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 67 TTHYGSLPQKAQHGRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 126 |
| Mus musculus | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 ||||||||||+| | ||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 63 TTHYGSLPQKSQHGRTQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 122 |
| Canis familiaris | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 | ||||||||+| ||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 67 TAHYGSLPQKSQHGRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 126 |
| Rattus norvegicus | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 ||||||||||+| | ||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 65 TTHYGSLPQKSQ--RTQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 122 |
| Cavia porcellus | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 ||||||||||+| | ||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 60 TTHYGSLPQKSQ--RSQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 117 |
| Homo sapiens | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 | ||||||||+ | | ||||||||||||||#|||||||||||||||||||||||||||+|| Sbjct 200 TAHYGSLPQKSHG-RTQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQRPG 258 |
| synthetic construct | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 | ||||||||+ | | ||||||||||||||#|||||||||||||||||||||||||||+|| Sbjct 67 TAHYGSLPQKSHG-RTQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQRPG 125 |
| Pongo pygmaeus | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 | ||||||||+ | | ||||||||||||||#|||||||||||||||||||||||||||+|| Sbjct 67 TAHYGSLPQKSHG-RTQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQRPG 125 |
| Rattus norvegicus | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 ||||||||||+| | ||||||||||||||#||||||||||||||||||||||| + | Sbjct 65 TTHYGSLPQKSQ--RTQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGGRDSRSG 122 |
| Gallus gallus | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 +| ||+||++| || |+|||||||||||#+|||||| | |||||||+||||| || ||| Sbjct 64 ASHVGSIPQRSQHGRPGDDNPVVHFFKNIV#SPRTPPPMQAKGRGLSLTRFSWGGEGHKPG 123 |
| Bos taurus | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 |||||||||||| ||||||||||||||||#||||||||||| |||||||| Sbjct 85 TTHYGSLPQKAQHGRPQDENPVVHFFKNIV#TPRTPPPSQGK-----------GAEGQKPG 133 |
| Homo sapiens | Query 64 TTHYGSLPQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKPG 123 | ||||||||+ | | ||||||||||||||#||||||||||| |||||+|| Sbjct 93 TAHYGSLPQKSHG-RTQDENPVVHFFKNIV#TPRTPPPSQGK-----------GAEGQRPG 140 |
| Gekko japonicus | Query 64 TTHYGSLPQKAQGH----RPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEG 119 +| ||| | | |+|||||||||||#+|||||| | |||||| |||||| | Sbjct 64 VSHVSSLPHPRSQHGRYGRYVDDNPVVHFFKNIV#SPRTPPPMQAKGRGLSFSRFSWGGET 123 Query 120 QKPG 123 | | Sbjct 124 PKHG 127 |
| Xenopus laevis | Query 78 RPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKP 122 | |||||||||+|||#+|||||||| | |||||+||||||+| +| Sbjct 84 RHVDENPVVHFFRNIV#SPRTPPPSQPK-RGLSLARFSWGADGHRP 127 |
| Xenopus laevis | Query 71 PQKAQGHRPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLSLSRFSWGAEGQKP 122 | | | | |+|||||||+|||#+|||||||| | || |||||||| || Sbjct 78 PYHAHG-RHVDDNPVVHFFRNIV#SPRTPPPSQPK-RG--FSRFSWGAENHKP 125 |
| Heterodontus francisci | Query 78 RPQDENPVVHFFKNIV#TPRTPPPSQGKGRGLS--LSRFSWGAEGQKP 122 | |++ |||||||++#+|+ | | | | +++| || +||+| Sbjct 68 RQTDDSAVVHFFKNMM#SPKKAPVQQKARSGASRAITKFIWGTDGQRP 114 |
| cattle, brain, Peptide Partial, 15 aa, segment 2 of 3 | Query 74 AQGHRPQDENPVVHF 88 ||||||||||||||| Query 74 AQGHRPQDENPVVHF 88 |
| Tetraodon nigroviridis | Query 71 PQKAQGHRPQD---ENPVVHFFKNIV#TPRTPPPSQ 102 |||| |+ || |||||+ ||#|| || |+ Sbjct 138 PQKASATSPRKRGAENAVVHFFRTIV#TP-APPKSR 171 |
| Danio rerio | Query 68 GSLPQKAQGHRPQDENPVVHFFKNIV-#TPRTPPPSQGKGRGLS 109 | | + | | |||||||++ | #+|| | |+|+ | | Sbjct 39 GKRPHHSSTRRRGDVNPVVHFFRSFVS#SPR--PKSRGESRSRS 79 |
[Site 4] HFFKNIVTPR96-TPPPSQGKGR
Arg96 Thr
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| His87 | Phe88 | Phe89 | Lys90 | Asn91 | Ile92 | Val93 | Thr94 | Pro95 | Arg96 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr97 | Pro98 | Pro99 | Pro100 | Ser101 | Gln102 | Gly103 | Lys104 | Gly105 | Arg106 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| YGSLPQKAQGHRPQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQKPGFGY |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 127.00 | 20 | MBP_BOVIN Myelin basic protein (MBP) (Myelin A1 p |
| 2 | Sus scrofa | 120.00 | 1 | myelin basic protein |
| 3 | Canis familiaris | 119.00 | 1 | PREDICTED: similar to Myelin basic protein (MBP) |
| 4 | Mus musculus | 117.00 | 6 | myelin basic protein isoform 3 |
| 5 | Homo sapiens | 116.00 | 6 | Golli-mbp isoform 1 |
| 6 | Rattus norvegicus | 114.00 | 8 | myelin basic protein |
| 7 | Pongo pygmaeus | 114.00 | 2 | hypothetical protein |
| 8 | Cavia porcellus | 114.00 | 1 | myelin basic protein; MBP |
| 9 | synthetic construct | 113.00 | 3 | myelin basic protein |
| 10 | Gallus gallus | 97.40 | 1 | myelin basic protein |
| 11 | Rattus norvegicus | 95.90 | 1 | myelin basic protein isoform 5 |
| 12 | Bos taurus | 90.90 | 1 | MBP protein |
| 13 | Homo sapiens | 82.00 | 1 | myelin basic protein isoform 2 |
| 14 | Xenopus laevis | 77.80 | 1 | hypothetical protein LOC734401 |
| 15 | Gekko japonicus | 77.40 | 1 | GekBS065P |
| 16 | Xenopus laevis | 67.00 | 1 | myelin basic protein |
| 17 | Heterodontus francisci | 48.90 | 1 | MBP_HETFR Myelin basic protein (MBP) gi |
| 18 | cattle, brain, Peptide Partial, 15 aa, segment 2 of 3 | 35.80 | 1 | clathrin assembly protein=myelin basic protein (M |
| 19 | Tetraodon nigroviridis | 33.90 | 1 | unnamed protein product |
| 20 | cattle, brain, Peptide Partial, 17 aa, segment 3 of 3 | 32.70 | 1 | clathrin assembly protein=myelin basic protein (M |
| 21 | Danio rerio | 31.20 | 1 | myelin basic protein |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 |
| Sus scrofa | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 ||||||||| |||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 70 YGSLPQKAQHGRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 129 |
| Canis familiaris | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 |||||||+| |||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 70 YGSLPQKSQHGRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 129 |
| Mus musculus | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 |||||||+| | |||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 66 YGSLPQKSQHGRTQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 125 |
| Homo sapiens | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 |||||||+ | | |||||||||||||||||#||||||||||||||||||||||||+||||| Sbjct 203 YGSLPQKSHG-RTQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQRPGFGY 261 |
| Rattus norvegicus | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 |||||||+| | |||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 68 YGSLPQKSQ--RTQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 125 |
| Pongo pygmaeus | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 |||||||+ | | |||||||||||||||||#||||||||||||||||||||||||+||||| Sbjct 70 YGSLPQKSHG-RTQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQRPGFGY 128 |
| Cavia porcellus | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 |||||||+| | |||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 63 YGSLPQKSQ--RSQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 120 |
| synthetic construct | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 |||||||+ | | |||||||||||||||||#||||||||||||||||||||||||+||||| Sbjct 70 YGSLPQKSHG-RTQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQRPGFGY 128 |
| Gallus gallus | Query 68 GSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFG 125 ||+||++| || |+|||||||||||+||#|||| | |||||||+||||| || |||+| Sbjct 68 GSIPQRSQHGRPGDDNPVVHFFKNIVSPR#TPPPMQAKGRGLSLTRFSWGGEGHKPGYG 125 |
| Rattus norvegicus | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPG 123 |||||||+| | |||||||||||||||||#|||||||||||||||||||| + | Sbjct 68 YGSLPQKSQ--RTQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGGRDSRSG 122 |
| Bos taurus | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 ||||||||| |||||||||||||||||||#|||||||| ||||||||||| Sbjct 88 YGSLPQKAQHGRPQDENPVVHFFKNIVTPR#TPPPSQGK-----------GAEGQKPGFGY 136 |
| Homo sapiens | Query 67 YGSLPQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFGY 126 |||||||+ | | |||||||||||||||||#|||||||| |||||+||||| Sbjct 96 YGSLPQKSHG-RTQDENPVVHFFKNIVTPR#TPPPSQGK-----------GAEGQRPGFGY 143 |
| Xenopus laevis | Query 78 RPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFG 125 | |||||||||+|||+||#|||||| | |||||+||||||+| +| +| Sbjct 84 RHVDENPVVHFFRNIVSPR#TPPPSQPK-RGLSLARFSWGADGHRPCYG 130 |
| Gekko japonicus | Query 78 RPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFG 125 | |+|||||||||||+||#|||| | |||||| |||||| | | |+| Sbjct 82 RYVDDNPVVHFFKNIVSPR#TPPPMQAKGRGLSFSRFSWGGETPKHGYG 129 |
| Xenopus laevis | Query 71 PQKAQGHRPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLSLSRFSWGAEGQKPGFG 125 | | | | |+|||||||+|||+||#|||||| | || |||||||| || +| Sbjct 78 PYHAHG-RHVDDNPVVHFFRNIVSPR#TPPPSQPK-RG--FSRFSWGAENHKPYYG 128 |
| Heterodontus francisci | Query 78 RPQDENPVVHFFKNIVTPR#TPPPSQGKGRGLS--LSRFSWGAEGQKPGFG 125 | |++ |||||||+++|+# | | | | +++| || +||+| +| Sbjct 68 RQTDDSAVVHFFKNMMSPK#KAPVQQKARSGASRAITKFIWGTDGQRPHYG 117 |
| cattle, brain, Peptide Partial, 15 aa, segment 2 of 3 | Query 74 AQGHRPQDENPVVHF 88 ||||||||||||||| Query 74 AQGHRPQDENPVVHF 88 |
| Tetraodon nigroviridis | Query 71 PQKAQGHRPQD---ENPVVHFFKNIVTPR#TPPPSQ 102 |||| |+ || |||||+ |||| # || |+ Sbjct 138 PQKASATSPRKRGAENAVVHFFRTIVTP-#APPKSR 171 |
| cattle, brain, Peptide Partial, 17 aa, segment 3 of 3 | Query 113 FSWGAEGQKPGFGY 126 |||||||||||||| Query 113 FSWGAEGQKPGFGY 126 |
| Danio rerio | Query 68 GSLPQKAQGHRPQDENPVVHFFKNIV-TPR#TPPPSQGKGRGLS 109 | | + | | |||||||++ | +||# | |+|+ | | Sbjct 39 GKRPHHSSTRRRGDVNPVVHFFRSFVSSPR#--PKSRGESRSRS 79 |
* References
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